2021

Alhujaily, Muhanad Musaad M., Abbas, Hafsa, Xue, Mingzhan, de la Fuente, Alberto, Rabbani, Naila and Thornalley, Paul J. (2021) Studies of glyoxalase 1-linked multidrug resistance reveal glycolysis-derived reactive metabolite, methylglyoxal, is a common contributor in cancer chemotherapy targeting the spliceosome. Frontiers in Oncology, 11 . 748698. doi:10.3389/fonc.2021.748698

2018

Rabbani, Naila, Xue, Mingzhan, Weickert, Martin O. and Thornalley, Paul J. (2018) Multiple roles of glyoxalase 1-mediated suppression of methylglyoxal glycation in cancer biology—involvement in tumour suppression, tumour growth, multidrug resistance and target for chemotherapy. Seminars in Cancer Biology, 49 . pp. 83-93. doi:10.1016/j.semcancer.2017.05.006

Hariton, Florence A. G., Xue, Mingzhan, Rabbani, Naila, Fowler, Mark and Thornalley, Paul J. (2018) Sulforaphane delays fibroblast senescence by curbing cellular glucose uptake, increased gycolysis, and oxidative damage. Oxidative Medicine and Cellular Longevity, 2018 . pp. 1-16. doi:10.1155/2018/5642148

2017

Xue, Mingzhan, Shafie, Alaa, Qaiser, Talha, Rajpoot, Nasir M., Kaltsas, Gregory, Gopalakrishnan, Kishore, Fisk, Adrian, Dimitriadis, Georgios K., Grammatopoulos, Dimitris, Rabbani, Naila, Thornalley, Paul J., Weickert, Martin O. and James, Sean G. (2017) Glyoxalase 1 copy number variation in patients with well differentiated gastroentero-pancreatic neuroendocrine tumours (GEP-NET). Oncotarget, 8 . pp. 76961-76973. doi:10.18632/oncotarget.20290

2016

Shafie, Alaa, Xue, Mingzhan, Barker, Guy C., Zehnder, Daniel, Thornalley, Paul J. and Rabbani, Naila (2016) Reappraisal of putative glyoxalase 1-deficient mouse and dicarbonyl stress on embryonic stem cells in vitro. Biochemical Journal, 473 (22). pp. 4255-4270. doi:10.1042/BCJ20160691

Rabbani, Naila, Xue, Mingzhan and Thornalley, Paul J. (2016) Methylglyoxal-induced dicarbonyl stress in aging and disease : first steps towards glyoxalase 1-based treatments. Clinical Science, 130 (19). pp. 1677-1696. doi:10.1042/CS20160025

Zhang, Fang, Masania, Jinit , Anwar, Attia, Xue, Mingzhan, Zehnder, Daniel, Kanji, Hemali, Rabbani, Naila and Thornalley, Paul J. (2016) The uremic toxin oxythiamine causes functional thiamine deficiency in end-stage renal disease by inhibiting transketolase activity. Kidney International, 90 (2). pp. 396-403. doi:10.1016/j.kint.2016.03.010

Rabbani, Naila, Xue, Mingzhan and Thornalley, Paul J. (2016) Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics. Glycoconjugates Journal, 33 . 513. doi:10.1007/s10719-016-9705-z

Xue, Mingzhan, Weickert, Martin O., Qureshi, S. A., Kandala, Ngianga-Bakwin, Anwar, Attia, Waldron, Molly, Shafie, Alaa, Messenger, David, Fowler, Mark, Jenkins, Gail, Rabbani, Naila and Thornalley, Paul J. (2016) Improved glycemic control and vascular function in overweight and obese subjects by glyoxalase 1 inducer formulation. Diabetes . db160153. doi:10.2337/db16-0153

2015

Xue, Mingzhan, Momiji, Hiroshi, Rabbani, Naila, Barker, Guy C., Bretschneider, Till, Shmygol, Anatoly, Rand, D. A. (David A.) and Thornalley, Paul J. (2015) Frequency modulated translocational oscillations of Nrf2 mediate the antioxidant response element cytoprotective transcriptional response. Antioxidants & Redox Signaling, 23 (7). pp. 613-629. doi:10.1089/ars.2014.5962

Xue, Mingzhan, Momiji, Hiroshi, Rabbani, Naila, Bretschneider, Till, Rand, D. A. (David A.) and Thornalley, Paul J. (2015) Frequency modulated translocational oscillations of Nrf2, a transcription factor functioning like a wireless sensor. Biochemical Society Transactions, 43 (4). pp. 669-673. doi:10.1042/BST20150060

2014

Xue, Mingzhan, Rabbani, Naila and Thornalley, Paul J. (2014) Measurement of glyoxalase gene expression. Biochemical Society Transactions, 42 (2). pp. 495-499. 495. doi:10.1042/BST20140026

Shafie, Alaa, Xue, Mingzhan, Thornalley, Paul J. and Rabbani, Naila (2014) Copy number variation of glyoxalase I. Biochemical Society Transactions, Volume 42 (Number 2). pp. 500-503. doi:10.1042/BST20140011

2012

Xue, Mingzhan, Rabbani, Naila, Momiji, Hiroshi, Imbasi, Precious, Anwar, M. Maqsud, Kitteringham, Neil, Park, B. Kevin, Souma, Tomokazu, Moriguchi, Takashi, Yamamoto, Masayuki and Thornalley, Paul J. (2012) Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation. The Biochemical journal, Vol.443 (No.1). pp. 213-22. doi:10.1042/BJ20111648

2011

Xue, Mingzhan, Rabbani, Naila and Thornalley, Paul J. (2011) Glyoxalase in ageing. Seminars in Cell and Developmental Biology, Vol.22 (No.3). pp. 293-301. doi:10.1016/j.semcdb.2011.02.013

Thornalley, Paul J., Xue, Mingzhan and Rabbani, Naila (2011) Role of NRF2 and the antistress gene response in countering oxidative stress in diabetes mellitus. Clinical Chemistry and Laboratory Medicine, Vol.49 (Supp.1). S52-S52.

Rabbani, Naila, Godfrey, L. (Lisa), Xue, Mingzhan, Shaheen, Fozia, Geoffrion, M., Milne, Ross and Thornalley, Paul J. (2011) Glycation of LDL by methylglyoxal increases arterial atherogenicity : a possible contributor to increased risk of cardiovascular disease in diabetes. Diabetes, Vol.60 (No.7). pp. 1973-1980. doi:10.2337/db11-0085

Thornalley, Paul J., Xue, Mingzhan and Rabbani, Naila (2011) Methodologies for in-vitro and in-vivo activity of bioactive compounds. In: Terry, Leon A. (Leon Alexander), (ed.) Health-promoting properties of fruits and vegetables. Wallingford, Oxfordshire ; Cambridge, MA: CAB. ISBN 9781845935283

2009

Thornalley, Paul J., Xue, Mingzhan and Rabbani, Naila (2009) Involvement of transcription factor nrf2 and antioxidant response element linked gene expression in countering oxidative stress in diabetes. In: 34th Congress of the Federation of European Biochemical Societies, Prague, Czech Republic, July 04-09, 2009. Published in: FEBS Journal, Vol.276 (Suppl. 1). pp. 79-80. ISSN 1742-464x. doi:10.1111/j.1742-4658.2009.07046.x

Xue, Mingzhan, Antonysunil, Adaikalakoteswari, Rabbani, Naila and Thornalley, Paul J. (2009) Protein damage in the ageing process : advances in quantitation and the importance of enzymatic defences. In: Redox metabolism and longevity relationships in animals and plants. SEB experimental biology series, Vol.62 . New York ; Abingdon [England]: Taylor & Francis Group, pp. 227-265. ISBN 9780415419543

2008

Xue, Mingzhan, Qian, Qingwen, Antonysunil, Adaikalakoteswari, Rabbani, Naila, Babaei-Jadidi, Roya and Thornalley, Paul J. (2008) Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease. Diabetes, Volume 57 (Number 10). pp. 2809-2817. doi:10.2337/db06-1003

Xue, Mingzhan, Thornalley, Paul J. and Rabbani, Naila (2008) LDL glycated by methylglyoxal to physiological extent in vitro has increased binding of proteoglycan without impairment of LDL receptor binding. In: 43rd Annual Meeting of the European Association for the Study of Diabetes, Amsterdam, Netherlands, Sep 18-21, 2007. Published in: Diabetologia, Vol.51 (Suppl.1). S299-S299. ISSN 0012-186X.