2022

(2022) Selective activation of Gαob by an adenosine A 1 receptor agonist elicits analgesia without cardiorespiratory depression. Nature Communications, 13 (1). 4150. doi:10.1038/s41467-022-31652-2 ISSN 2041-1723.

2016

Knight, Anthony, Hemmings, Jennifer L., Winfield, Ian J., Leuenberger, Michele, Frattini, Eugenia, Frenguelli, Bruno G., Dowell, Simon J., Lochner, Martin and Ladds, Graham (2016) Discovery of novel adenosine receptor agonists that exhibit subtype selectivity. Journal of Medicinal Chemistry, 59 (3). pp. 947-964. doi:10.1021/acs.jmedchem.5b01402 ISSN 0022-2623.

2015

Prokic, Emma J., Weston, Cathryn, Yamawaki, Naoki , Hall, Stephen D., Jones, Roland S. G., Stanford, Ian M., Ladds, Graham and Woodhall, Gavin L. (2015) Cortical oscillatory dynamics and benzodiazepine-site modulation of tonic inhibition in fast spiking interneurons. Neuropharmacology, 95 . pp. 192-205. doi:10.1016/j.neuropharm.2015.03.006 ISSN 0028-3908.

Croft, Wayne D., Elliott, Charles M., Ladds, Graham, Stinner, Björn, Venkataraman, Chandrasekhar and Weston, Cathryn (2015) Parameter identification problems in the modelling of cell motility. Journal of Mathematical Biology, 71 (2). pp. 399-436. doi:10.1007/s00285-014-0823-6 ISSN 0303-6812.

Lockley, Robert, Ladds, Graham and Bretschneider, Till (2015) Image based validation of dynamical models for cell reorientation. Cytometry Part A, 87 (6). pp. 471-480. doi:10.1002/cyto.a.22600 ISSN 1552-4922.

2014

Lock, Antonia, Forfar, Rachel, Weston, Cathryn, Bowsher, L, Upton, Graham J.G., Reynolds, Christopher A., Ladds, Graham and Dixon, Ann M. (2014) One motif to bind them : a small-XXX-small motif affects transmembrane domain 1 oligomerization, function, localization, and cross-talk between two yeast GPCRs. Biochimica et Biophysica Acta (BBA) - Biomembranes, Volume 1838 (Number 12). pp. 3036-3051. doi:10.1016/j.bbamem.2014.08.019 ISSN 0005-2736.

Weston, Cathryn, Poyner, David R., Patel, Vanlata H., Dowell, Scott F. and Ladds, Graham (2014) Investigating G protein signalling bias at the glucagon-like peptide-1 receptor in yeast. British Journal of Pharmacology, 171 (15). pp. 3651-3665. doi:10.1111/bph.12716 ISSN 1476-5381.

2013

Weston, Cathryn, Bond, Michael, Croft, Wayne D. and Ladds, Graham (2013) The coordination of cell growth during fission yeast mating requires Ras1-GTP hydrolysis. PLoS One, Volume 8 (Number 10). e77487. doi:10.1371/journal.pone.0077487 ISSN 1932-6203.

Croft, Wayne D., Hills, Claire E., McCann, Eilish Clare, Bond, Michael, Esparza Franco, Manuel A., Bennett, Jeanette, Rand, D. A. (David A.), Davey, John and Ladds, Graham (2013) A physiologically required G protein-coupled receptor (GPCR)-regulator of G protein signaling (RGS) interaction that compartmentalizes RGS activity. Journal of Biological Chemistry, Volume 288 (Number 38). pp. 27327-27342. doi:10.1074/jbc.M113.497826 ISSN 0021-9258.

Mos, Magdalena, Godfrey, Emma L., Esparza Franco, Manuel A., Richardson, Kathryn, Davey, John and Ladds, Graham (2013) The role of the RACK1 ortholog Cpc2p in modulating pheromone-induced cell cycle arrest in fission yeast. PLoS One, Volume 8 (Number 7). Article number e65927. doi:10.1371/journal.pone.0065927 ISSN 1932-6203.

Bond, M., Croft, Wayne D., Tyson, Richard, Bretschneider, Till, Davey, John and Ladds, Graham (2013) Quantitative analysis of human ras localization and function in the fission yeast Schizosaccharomyces pombe. Yeast, Volume 30 (Number 4). pp. 145-156. doi:10.1002/yea.2949 ISSN 0749-503X.

2010

Li, Shuyu, Spooner, Robert A. , Allen, Stuart C. H., Guise, Christopher P., Ladds, Graham, Schnöder, Tina, Schmitt, Manfred J., Lord, Mike and Roberts, L. M. (Lynne M.) (2010) Folding-competent and folding-defective forms of Ricin A chain have different fates following retrotranslocation from the endoplasmic reticulum. Molecular Biology of the Cell, Vol.21 (No.15). pp. 2543-2554. doi:10.1091/mbc.E09-08-0743 ISSN 1939-4586.

2009

Smith, Benjamin, Hill, Claire, Godfrey, Emma L., Rand, D. A., Berg, Hugo van den, Thornton, Steven, Hodgkin, Matthew N., Davey, John and Ladds, Graham (2009) Dual positive and negative regulation of GPCR signaling by GTP hydrolysis. Cellular Signalling, Vol.21 (No.7). pp. 1151-1160. doi:10.1016/j.cellsig.2009.03.004 ISSN 0898-6568.

Ladds, Graham, Zervou, Sevasti I., Vatish, Manu, Thornton, Steven and Davey, John (2009) Regulators of G protein signalling proteins in the human myometrium. European Journal of Pharmacology, Vol.610 (No.1-3). pp. 23-28. doi:10.1016/j.ejphar.2009.03.042 ISSN 0014-2999.

Hill, Claire, Goddard, Alan, Ladds, Graham and Davey, John (2009) The cationic region of Rhes mediates its interactions with specific Gβ subunits. Cellular Physiology and Biochemistry, Vol.23 (No.1-3). pp. 1-8. doi:10.1159/000204075 ISSN 1015-8987.

2008

Wright, Michelle H., Farquhar, Michelle J., Aletrari, Mina-Olga, Ladds, Graham and Hodgkin, Matthew N. (2008) Identification of caspase 3 motifs and critical aspartate residues in human phospholipase D1b and phospholipase D2a. Biochemical and Biophysical Research Communications, Vol.369 (No.2). pp. 478-484. doi:10.1016/j.bbrc.2008.02.064 ISSN 0006-291X.

Wright, Michelle H., Farquhar, Michelle J., Aletrari, Mina-Olga , Ladds, Graham and Hodgkin, Matthew N. (2008) Identification of caspase 3 motifs and critical aspartate residues in human Phospholipase D1b and Phopsholipase D2a. Biochemical and Biophysical Research Communications, Vol.369 (No.2). pp. 478-484. doi:10.1016/j.bbrc.2008.02.064 ISSN 0006-291x.

Hill, Claire, Brownlie, Zoe, Davey, John, Milligan, Graeme and Ladds, Graham (2008) Isolation and characterization of a novel human RGS mutant displaying gain-of-function activity. Cellular Signalling, Vol.20 (No.2). pp. 323-336. doi:10.1016/j.cellsig.2007.10.016 ISSN 0898-6568.

2007

Allen, Stuart C. H., Moore, Katherine A. H., Marsden, Catherine J., Fülöp, Vilmos, Moffat, Kevin G., Lord, Mike, Ladds, Graham and Roberts, L. M. (Lynne M.) (2007) The isolation and characterization of temperature-dependent ricin A chain molecules in Saccharomyces cerevisiae. FEBS JOURNAL, 274 (21). pp. 5586-5599. doi:10.1111/j.1742-4658.2007.06080.x ISSN 1742-464X.

Allen, Stuart C. H., Moore, Katherine A. H., Marsden, Catherine J., Fülöp, Vilmos, Moffat, Kevin G., Lord, Mike, Ladds, Graham and Roberts, L. M. (Lynne M.) (2007) The isolation and characterisation of temperature-dependent Ricin A chain molecules in Saccharomyces cerevisiae. FEBS Journal, Vol.274 (No.21). pp. 5586-5599. doi:10.1111/j.1742-4658.2007.06080.x ISSN 1742-464x.

Farquhar, Michelle J., Powner, D. J., Levine, B. A., Wright, M. H., Ladds, Graham and Hodgkin, Matthew N. (2007) Interaction of PLD1b with actin in antigen-stimulated mast cells. Cellular Signalling, Vol.19 (No.2). pp. 349-358. doi:10.1016/j.cellsig.2006.07.016 ISSN 0898-6568.

2006

Goddard, Alan, Ladds, Graham, Forfar, Rachel and Davey, John (2006) Identification of Gnr1p, a negative regulator of Got signalling in Schizosaccharomyces pombe, and its complementation by human G beta subunits. FUNGAL GENETICS AND BIOLOGY, 43 (12). pp. 840-851. doi:10.1016/j.fgb.2006.06.005 ISSN 1087-1845.

Das, Anamika, Forfar, Rachel, Ladds, Graham and Davey, John (2006) Combined use of two transcriptional reporters improves signalling assays receptors in fission yeast. Yeast, Volume 23 (Number 12). pp. 889-897. doi:10.1002/yea.1402 ISSN 0749-503X.

Ladds, Graham, Goddard, Alan, Hill, Claire, Thornton, Steven and Davey, John (2006) Differential effects of RGS proteins on Gαq and Gα11 activity. Cellular Signalling, Vol.19 (No.1). pp. 103-113. doi:10.1016/j.cellsig.2006.05.027 ISSN 0898-6568.

Ladds, Graham (2006) Activators and regulators of G protein signalling - Introduction. Seminars in Cell & Developmental Biology, Volume 17 (Number 3). p. 333. doi:10.1016/j.semcdb.2006.03.004

Hill, Claire, Goddard, Alan, Davey, John and Ladds, Graham (2006) Investigating RGS proteins in yeast. Seminars in Cell & Developmental Biology, Volume 17 (Number 3). pp. 352-362. doi:10.1016/j.semcdb.2006.03.008