Journal Article

Jacomin, Anne-Claire, Gohel, Raksha, Hussain, Zunoon, Varga, Agnes, Maruzs, Tamas, Eddison, Mark, Sica, Margaux, Jain, Ashish, Moffat, Kevin G., Johansen, Terje, Jenny, Andreas, Juhasz, Gabor and Nezis, Ioannis P. (2021) Degradation of arouser by endosomal microautophagy is essential for adaptation to starvation in Drosophila. Life Science Alliance, 4 (2). e202000965. doi:10.26508/lsa.202000965 ISSN 2575-1077.

Karikari, Thomas K., Keeling, Sophie, Hill, Emily, Lantero Rodrı́guez, Juan, Nagel, David A., Becker, Bruno, Höglund, Kina, Zetterberg, Henrik, Blennow, Kaj, Hill, Eric J. and Moffat, Kevin G. (2020) Extensive plasmid library to prepare Tau protein variants and study their functional biochemistry. ACS Chemical Neuroscience, 11 (19). pp. 3117-3129. doi:10.1021/acschemneuro.0c00469 ISSN 1948-7193.

Karikari, Thomas K., Thomas, Rachel and Moffat, Kevin G. (2020) The C291R Tau variant forms different types of protofibrils. Frontiers in Molecular Neuroscience, 13 . 39. doi:10.3389/fnmol.2020.00039 ISSN 1662-5099.

Hill, Emily, Wall, Mark J., Moffat, Kevin G. and Karikari , T. (2020) Understanding the pathophysiological actions of tau oligomers : a critical review of current electrophysiological methods. Frontiers in Molecular Neuroscience, 13 . 155. doi:10.3389/fnmol.2020.00155 ISSN 1662-5099.

Hill, Emily, Karikaria, Thomas K., Moffat, Kevin G., Richardson, Magnus J. E. and Wall, Mark J. (2019) Introduction of tau oligomers into cortical neurons alters action potential dynamics and disrupts synaptic transmission and plasticity. eNeuro, 6 (5). 0166. doi:10.1523/ENEURO.0166-19.2019 ISSN 2373-2822.

Karikari, Thomas K., Nagel, David A., Grainger, Alastair, Clarke-Bland, Charlotte, Crowe, James, Hill, Eric J. and Moffat, Kevin G. (2019) Distinct conformations, aggregation and cellular internalization of different tau strains. Frontiers in Cellular Neuroscience, 13 . 296. doi:10.3389/fncel.2019.00296 ISSN 1662-5102.

Karikari, Thomas K., Nagel, David A., Grainger, Alastair, Clarke-Bland, Charlotte, Hill, Eric J. and Moffat, Kevin G. (2019) Preparation of stable tau oligomers for cellular and biochemical studies. Analytical Biochemistry, 566 . pp. 67-74. doi:10.1016/j.ab.2018.10.013 ISSN 0003-2697.

Galasso, Alessia, Cameron, Charles S., Frenguelli, Bruno G. and Moffat, Kevin G. (2017) An AMPK-dependent regulatory pathway in tau-mediated toxicity. Biology Open, 6 (10). pp. 1434-1444. doi:10.1242/bio.022863 ISSN 2046-6390.

Karikari, Thomas K., Turner, Alexandra, Stass, Robert, Lee, Leonie C.Y., Wilson, Bethany, Nagel, David A., Hill, Eric J. and Moffat, Kevin G. (2016) Expression and purification of tau protein and its frontotemporal dementia variants using a cleavable histidine tag. Protein Expression and Purification, 130 . pp. 44-54. doi:10.1016/j.pep.2016.09.009 ISSN 1046-5928.

Pawar, Vidya, De, Antara, Briggs, Laura, Omar, Mahmoud M., Sweeney, Sean T., Lord, Mike, Roberts, L. M. (Lynne M.), Spooner, Robert A. and Moffat, Kevin G. (2011) RNAi screening of Drosophila (Sophophora) melanogaster S2 cells for ricin sensitivity and resistance. Journal of Biomolecular Screening, Vol.16 (No.4). pp. 436-442. doi:10.1177/1087057110397890 ISSN 1087-0571.

Eddison, Mark, Guarnieri, Douglas J., Cheng, Ling, Liu, Che-Hsiung, Moffat, Kevin G., Davis, Graeme, Ph. D. and Heberlein, Ulrike (2011) arouser reveals a role for synapse number in the regulation of ethanol sensitivity. Neuron, Vol.70 (No.5). pp. 979-990. doi:10.1016/j.neuron.2011.03.030 ISSN 0896-6273.

Price, Nigel T., Jackson, Vicky N., Müller, Jürgen, Moffat, Kevin G., Matthews, Karen L., Orton, Tim and Zammit, Victor A. (2010) Alternative exon usage in the single CPT1 gene of Drosophila generates functional diversity in the kinetic properties of the enzyme. Differential expression of alternatively spliced variants in Drosophila tissues. Journal of Biological Chemistry, Vol.285 (No.11). pp. 7857-7865. doi:10.1074/jbc.M109.072892 ISSN 0021-9258.

Muraro, Nara I., Weston, Andrew J., Gerber, Andre P., Luschnig, Stefan, Moffat, Kevin G. and Baines, Richard A. (2008) Pumilio binds para mRNA and requires nanos and brat to regulate sodium current in drosophila motoneurons. Journal of Neuroscience, Vol.28 (No.9). pp. 2099-2109. doi:10.1523/JNEUROSCI.5092-07.2008 ISSN 0270-6474.

Allen, Stuart C. H., Moore, Katherine A. H., Marsden, Catherine J., Fülöp, Vilmos, Moffat, Kevin G., Lord, Mike, Ladds, Graham and Roberts, L. M. (Lynne M.) (2007) The isolation and characterization of temperature-dependent ricin A chain molecules in Saccharomyces cerevisiae. FEBS JOURNAL, 274 (21). pp. 5586-5599. doi:10.1111/j.1742-4658.2007.06080.x ISSN 1742-464X.

Allen, Stuart C. H., Moore, Katherine A. H., Marsden, Catherine J., Fülöp, Vilmos, Moffat, Kevin G., Lord, Mike, Ladds, Graham and Roberts, L. M. (Lynne M.) (2007) The isolation and characterisation of temperature-dependent Ricin A chain molecules in Saccharomyces cerevisiae. FEBS Journal, Vol.274 (No.21). pp. 5586-5599. doi:10.1111/j.1742-4658.2007.06080.x ISSN 1742-464x.

Allen, M. J., Drummond, J. A., Sweetman, D. J. and Moffat, Kevin G. (2007) Analysis of two P-element enhancer-trap insertion lines that show expression in the giant fibre neuron of Drosophila melanogaster. Genes, Brain and Behavior, Vol.6 (No.4). pp. 347-358. doi:10.1111/j.1601-183X.2006.00263.x ISSN 1601-1848.

Reeve, Simon, Carhan, Ahmet, Dee, Chris T. and Moffat, Kevin G. (2007) slowmo is required for Drosophila germline proliferation. Genesis: The Journal of Genetics and Development, Vol.45 (No.2). pp. 66-75. doi:10.1002/dvg.20265 ISSN 1526-954X.

Muraro, Nara I. and Moffat, Kevin G. (2006) Down-regulation of torp4a, encoding the Drosophila homologue of TorsinA, results in increased neuronal degeneration. JOURNAL OF NEUROBIOLOGY, 66 (12). pp. 1338-1353. doi:10.1002/neu.20313 ISSN 0022-3034.

Mee, Christopher J., Pym, Edward C. G., Moffat, Kevin G. and Baines, Richard A. (2004) Regulation of neuronal excitability through pumilio-dependent control of a sodium channel gene. Journal of Neuroscience, Vol.24 (No.40). pp. 8695-8703. doi:10.1523/JNEUROSCI.2282-04.2004 ISSN 0270-6474.

Carhan, Ahmet, Reeve, Simon, Dee, Chris T., Baines, Richard A. and Moffat, Kevin G. (2004) Mutation in slowmo causes defects in Drosophila larval locomotor behaviour. INVERTEBRATE NEUROSCIENCE, 5 (2). pp. 65-75. doi:10.1007/s10158-003-0028-y ISSN 1354-2516.

Marrus, Scott B., Portman, Scott L., Allen, Marcus James, Moffat, Kevin G. and DiAntonio, Aaron (2004) Differential localization of glutamate receptor subunits at the drosophila neuromuscular junction. Journal of Neuroscience, Vol.24 (No.6). pp. 1406-1415. doi:10.1523/JNEUROSCI.1575-03.2004 ISSN 0270-6474.

Allen, Marcus James, Shan, Xiaoliang, Caruccio, Phyllis, Froggett, Stephan J., Moffat, Kevin G. and Murphey, R. K. (1999) Targeted expression of truncated glued disrupts giant fiber synapse formation in Drosophila. Journal of Neuroscience, Vol.19 (No.21). pp. 9374-9384. ISSN 0270-6474.

Phelan, Pauline, Nakagawa, Madoka, Wilkin, Marian B., Moffat, Kevin G., O'Kane, Cahir J. and Bacon, J. P. (Jonathan P.) (1996) Mutations in shaking-B prevent electrical synapse formation in the Drosophila giant fiber system. Journal of Neuroscience, Vol.16 (No.3). pp. 1101-1113. ISSN 0270-6474.

Book Item

Hill, Emily, Moffat, Kevin G., Wall, Mark J., Zetterberg, Henrik, Blennow, Kaj and Karikari, Thomas K. (2023) Functional applications of stable Tau Oligomers in cell biology and electrophysiology studies. In: Protein Aggregation. Methods in Molecular Biology, 2551 . New York, NY: Humana, pp. 147-161. ISBN 9781071625972

Hill, Emily, Moffat, Kevin G., Wall, Mark J., Zetterberg, Henrik, Blennow, Kaj and Karikari, Thomas K. (2022) A validated method to prepare stable Tau Oligomers. In: Cieplak, A. S., (ed.) Protein Aggregation. Methods in Molecular Biology, 2551 . New York, NY: Humana, pp. 203-224. ISBN 9781071625965

Moffat, Kevin G. (2017) Biological Identity. In: Reconstructing Identity. Palgrave Macmillan, pp. 61-82. ISBN 9783319584263

Moffat, Kevin G. (2008) Drosophila genetics for the analysis of neurobiological disease. In: Drosophila: a toolbox for the study of neurodegenerative disease. SEB experimental biology series, Vol.60 . New York; Abingdon: Taylor & Francis Group, pp. 9-24. ISBN 978-0-4154-1185-1

Conference Item

Moffat, Kevin G., Patel, S. and Hultén, Maj A. (2009) Trisomy21, Down Syndrome and the origin of Alzheimer's disease. In: British Human Genetics Conference, University of Warwick, England, Aug 31 - Sep 02 2009. Published in: Journal of Medical Genetics, Vol.46 (Suppl. 1). S22-S22. ISSN 0022-2593.

De, Antara, Baines, Richard A. and Moffat, Kevin G. (2006) Pumilio: Role in regulation of neuronal excitability in Drosophila. In: UNSPECIFIED. Published in: JOURNAL OF NEUROGENETICS, 20 (3-4). pp. 109-110. ISSN 0167-7063.

Muraro, Nara I., Weston, Andrew, De, Antara, Moffat, Kevin G. and Baines, Richard A. (2006) Role of Pumilio, nanos, and brain tumor in the regulation of the sodium channel encoded by paralytic. In: UNSPECIFIED. Published in: JOURNAL OF NEUROGENETICS, 20 (3-4). pp. 183-184. ISSN 0167-7063.

Wright, Duncan E., Moffat, Kevin G. and Baines, Richard A. (2006) The impact of alternative splicing on the properties of the paralytic voltage-gated sodium channel. In: UNSPECIFIED. Published in: JOURNAL OF NEUROGENETICS, 20 (3-4). pp. 261-262. ISSN 0167-7063.

Journal Item

Caudron, Q., Lyn-Adams, Ceri Louise, Aston, John A. D., Frenguelli, Bruno G. and Moffat, Kevin G. (2010) Quantitative assessment of ommatidial distortion in Drosophila melanogaster : a tool to investigate genetic interactions. Journal of Neurogenetics, Vol.24 (No.1). p. 87.

Lyn-Adams, Ceri Louise, Frenguelli, Bruno G., Moffat, Kevin G. and Sutherland, Calum (2010) Regulation of tau-dependent toxicity by brain selective/SAD kinases. Journal of Neurogenetics, Vol.24 (No.1). p. 12.