2022

Embacher, Peter A., Germanova, Tsvetelina E., Roscioli, Emanuele, McAinsh, Andrew D. and Burroughs, Nigel J. (2022) Bayesian inference of multi-point macromolecular architecture mixtures at nanometre resolution. PLoS Computational Biology, 18 (12). e1010765. doi:10.1371/journal.pcbi.1010765 ISSN 1553-7358.

Currie, Cerys E., Ford, Emma, Benham Whyte, Lucy, Taylor, Deborah M., Mihalas, Bettina P., Erent, Muriel, Marston, Adele L., Hartshorne, Geraldine M. and McAinsh, Andrew D. (2022) The first mitotic division of human embryos is highly error prone. Nature Communications, 13 (1). 6755. doi:10.1038/s41467-022-34294-6 ISSN 2041-1723.

Currie, Cerys E., Ford, Emma, Whyte, Lucy Benham, Taylor, Deborah M., Mihalas, Bettina P., Erent, Muriel, Marston, Adele L., Hartshorne, Geraldine M. and McAinsh, Andrew D. (2022) Data for The first mitotic division of human embryos is highly error prone. [Dataset]

Castrogiovanni, Cédric, Inchingolo, Alessio, Harrison, Jonathan U., Dudka, Damian, Sen, Onur, Burroughs, Nigel John, McAinsh, Andrew D. and Meraldi, Patrick (2022) Evidence for a HURP/EB free mixed-nucleotide zone in kinetochore-microtubules. Nature Communications, 13 . 4704. doi:10.1038/s41467-022-32421-x ISSN 2041-1723.

Harrison, Jonathan, Sen, Onur, McAinsh, Andrew D. and Burroughs, Nigel John (2022) Kinetochore tracking in 3D from lattice light sheet imaging data with KiT. Bioinformatics, 38 (12). pp. 3315-3317. doi:10.1093/bioinformatics/btac330 ISSN 1460-2059.

2021

Germanova, Tsvetelina E., Roscioli, Emanuele, Harrison, Jonathan, McAinsh, Andrew D. and Burroughs, Nigel John (2021) Subcellular Euclidean distance measurements with multicolor fluorescence localization imaging in cultured cells. STAR Protocols, 2 (4). 100774. doi:10.1016/j.xpro.2021.100774 ISSN 2666-1667.

Sen, Onur, Harrison, Jonathan, Burroughs, Nigel John and McAinsh, Andrew D. (2021) Kinetochore life histories reveal an Aurora-B-dependent error correction mechanism in anaphase. Developmental Cell, 56 (22). pp. 3082-3099. doi:10.1016/j.devcel.2021.10.007 ISSN 1534-5807.

2020

Roscioli, Emanuele, Germanova, Tsvetelina E., Smith, Christopher A., Embacher, Peter A., Erent, Muriel, Thompson, Amelia I., Burroughs, Nigel John and McAinsh, Andrew D. (2020) Ensemble-Level Organization of Human Kinetochores and Evidence for Distinct Tension and Attachment Sensors. Cell Reports, 31 (4). p. 107535. doi:10.1016/j.celrep.2020.107535 ISSN 2211-1247.

Auckland, Philip, Roscioli, Emanuele, Coker, H. L. E. and McAinsh, Andrew D. (2020) CENP-F stabilizes kinetochore-microtubule attachments and limits dynein stripping of corona cargoes. Journal of Cell Biology, 219 (5). e201905018. doi:10.1083/jcb.201905018 ISSN 0021-9525.

2018

Pesenti, Marion E., Prumbaum, Daniel, Auckland, Philip, Smith, Charlotte M., Faesen, Alex C., Petrovic, Arsen, Erent, Muriel, Maffini, Stefano, Pentakota, Satyakrishna, Weir, John R., Lin, Yu-Chih, Raunser, Stefan, McAinsh, Andrew D. and Musacchio, Andrea (2018) Reconstitution of a 26-Subunit human kinetochore reveals cooperative microtubule binding by CENP-OPQUR and NDC80. Molecular Cell, 71 (6). pp. 923-939. doi:10.1016/j.molcel.2018.07.038 ISSN 1097-2765.

Currie, Cerys E., Mora-Santos, Maria, Smith, Chris A., McAinsh, Andrew D. and Millar, Jonathan B.A. (2018) Bub1 is not essential for the checkpoint response to unattached kinetochores in diploid human cells. Current Biology, 28 (17). R929-R930. doi:10.1016/j.cub.2018.07.040 ISSN 0960-9822.

McHugh, Toni, Drechsler, Hauke, McAinsh, Andrew D., Carter, Nicholas J. and Cross, R. A. (2018) Kif15 functions as an active mechanical ratchet. Molecular Biology of the Cell, 29 (4). pp. 1743-1752. doi:10.1091/mbc.E18-03-0151 ISSN 1059-1524.

Dudka, Damian, Noatynska, Anna, Smith, Christopher A., Liaudet, Nicolas, McAinsh, Andrew D. and Meraldi, Patrick (2018) Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments. Nature Communications, 9 (1). doi:10.1038/s41467-018-04427-x ISSN 2041-1723.

Hatano, Tomoyuki, Alioto, Salvatore, Roscioli, Emanuele, Palani, Saravanan, Clarke, Scott T., Kamnev, Anton, Hernandez Fernaud, Juan Ramon, Sivashanmugam, Lavanya, Chapa y Lazo, Bernardo, Jones, Alexandra M., Robinson, Robert C., Sampath, Karuna, Mishima, Masanori, McAinsh, Andrew D., Goode, Bruce L. and Balasubramanian, Mohan K. (2018) Rapid production of pure recombinant actin isoforms in Pichia pastoris. Journal of Cell Science, 131 (8). jcs213827. doi:10.1242/jcs.213827 ISSN 1477-9137.

Currie, Cerys E., Mora-Santos, Maria, Smith, Chris, McAinsh, Andrew D. and Millar, Jonathan B. A. (2018) Bub1 is not required for the checkpoint response to unattached kinetochores in diploid human cells. Working Paper. Cold Spring Harbour: BioRXiv.

Smith, Chris A., Burroughs, Nigel John and McAinsh, Andrew D. (2018) Mitotic live-cell imaging at different timescales. In: Maiato, Helder and Schuh, Melina, (eds.) Mitosis and Meiosis Part B. Methods in Cell Biology, 145 . Cambridge, Massachuetts: Elsevier, pp. 1-27. ISBN 9780128141427

2017

Rhys, Alexander D., Monteiro, Pedro, Smith, Christopher Matthew, Vaghela, Malti, Arnandis, Teresa, Kato, Takuya, Leitinger, Birgit, Sahai, Erik, McAinsh, Andrew D., Charras, Guillaume and Godinho, Susana A. (2017) Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells. The Journal of Cell Biology, 217 (1). pp. 195-209. doi:10.1083/jcb.201704102 ISSN 0021-9525.

Sandu, Pamela, Crepin, Valerie F., Drechsler, Hauke, McAinsh, Andrew D., Frankel, Gad and Berger, Cedric N. (2017) The Enterohemorrhagic Escherichia coli effector EspW triggers actin remodeling in a Rac1-dependent manner. Infection and Immunity, 85 (9). e00244-17. doi:10.1128/IAI.00244-17 ISSN 0019-9567.

Auckland, Philip, Clarke, Nicholas I., Royle, Stephen J. and McAinsh, Andrew D. (2017) Congressing kinetochores progressively load Ska complexes to prevent force-dependent detachment. The Journal of Cell Biology, 216 (6). pp. 1623-1639. doi:10.1083/jcb.201607096 ISSN 0021-9525.

Maciejowski, John, Drechsler, Hauke, Grundner-Culemann, Kathrin, Ballister, Edward R., Rodriguez-Rodriguez, Jose-Antonio, Rodriguez-Bravo, Veronica, Jones, Mathew J. K., Foley, Emily, Lampson, Michael A., Daub, Henrik, McAinsh, Andrew D. and Jallepalli, Prasad V. (2017) Mps1 regulates kinetochore-microtubule attachment stability via the ska complex to ensure error-free chromosome segregation. Developmental Cell, 41 (2). 143-156.e6. doi:10.1016/j.devcel.2017.03.025 ISSN 1534-5807.

2016

Smith, Chris A., McAinsh, Andrew D. and Burroughs, Nigel John (2016) Human kinetochores are swivel joints that mediate microtubule attachments. eLife, 5 . e16159. doi:10.7554/eLife.16159 ISSN 2050-084X.

Armond, Jonathan W., Vladimirou, Elina, McAinsh, Andrew D. and Burroughs, Nigel John (2016) KiT : a MATLAB package for kinetochore tracking. Bioinformatics, 32 (12). pp. 1917-1919. doi:10.1093/bioinformatics/btw087 ISSN 1367-4803.

Drechsler, Hauke and McAinsh, Andrew D. (2016) Kinesin-12 motors cooperate to suppress microtubule catastrophes and drive the formation of parallel microtubule bundles. Proceedings of the National Academy of Sciences of the United States of America, 113 (12). E1635-E1644. doi:10.1073/pnas.1516370113 ISSN 0027-8424.

Patel, Jessica, Tan, S. L., Hartshorne, Geraldine M. and McAinsh, Andrew D. (2016) Unique geometry of sister kinetochores in human oocytes during meiosis I may explain maternal age-associated increases in chromosomal abnormalities. Biology Open, 5 (2). pp. 178-184. doi:10.1242/bio.016394 ISSN 2046-6390.

2015

Silió, Virginia, McAinsh, Andrew D. and Millar, Jonathan B. A. (2015) KNL1-Bubs and RZZ provide two separable pathways for checkpoint activation at human kinetochores. Developmental Cell, 35 (5). pp. 600-613. doi:10.1016/j.devcel.2015.11.012 ISSN 1534-5807.

Armond, Jonathan W., Harry, Edward, McAinsh, Andrew D. and Burroughs, Nigel John (2015) Inferring the forces controlling metaphase kinetochore oscillations by reverse engineering system dynamics. PLoS Computational Biology, 11 (11). e1004607. doi:10.1371/journal.pcbi.1004607 ISSN 1553-7358.

Burroughs, Nigel John, Harry, Edward and McAinsh, Andrew D. (2015) Super-resolution kinetochore tracking reveals the mechanisms of human sister kinetochore directional switching. eLife, 4 . e09500. doi:10.7554/eLife.09500 ISSN 2050-084X.

Auckland, Philip and McAinsh, Andrew D. (2015) Building an integrated model of chromosome congression. Journal of Cell Science, 128 (18). pp. 3363-3374. doi:10.1242/jcs.169367 ISSN 0021-9533.

Armond, Jonathan W., Vladimirou, Elina, Erent, Muriel, McAinsh, Andrew D. and Burroughs, Nigel John (2015) Probing microtubule polymerisation state at single kinetochores during metaphase chromosome motion. Journal of Cell Science, Volume 128 (Number 10). pp. 1991-2001. doi:10.1242/jcs.168682 ISSN 0021-9533.

Bancroft, James M., Auckland, Philip, Samora, C. P. and McAinsh, Andrew D. (2015) Chromosome congression is promoted by CENP-Q- and CENP-E-dependent pathways. Journal of Cell Science, 128 (1). pp. 171-184. doi:10.1242/jcs.163659 ISSN 0021-9533.

2014

McAinsh, Andrew D. (2014) How kinetochores CCAN resist force. Developmental Cell, Volume 30 (Number 6). pp. 637-638. doi:10.1016/j.devcel.2014.09.007 ISSN 1534-5807.

Drechsler, Hauke, McHugh, Toni, Singleton, Martin R., Carter, Nicholas J. and McAinsh, Andrew D. (2014) The kinesin-12 Kif15 is a processive track-switching tetramer. eLife, Volume 3 . Article number e01724. doi:10.7554/eLife.01724 ISSN 2050-084X.

Cross, R. A. and McAinsh, Andrew D. (2014) Prime movers : mechanochemistry of mitotic kinesins. Nature Reviews Molecular Cell Biology, Volume 15 . pp. 257-271. doi:10.1038/nrm3768 ISSN 1471-0072.

Vázquez-Novelle, María Dolores, Sansregret, Laurent, Dick, Amalie E., Smith, Christopher A., McAinsh, Andrew D., Gerlich, Daniel W. and Petronczki, Mark (2014) Cdk1 inactivation terminates mitotic checkpoint surveillance and stabilizes kinetochore attachments in anaphase. Current Biology, Volume 24 (Number 6). pp. 638-645. doi:10.1016/j.cub.2014.01.034 ISSN 0960-9822.

2013

Vladimirou, Elina , Mchedlishvili, Nunu, Gasic, Ivana, Armond, Jonathan W., Samora, Catarina P., Meraldi, Patrick and McAinsh, Andrew D. (2013) Nonautonomous movement of chromosomes in mitosis. Developmental Cell, Volume 27 (Number 1). pp. 60-71. doi:10.1016/j.devcel.2013.08.004 ISSN 1534-5807.

(2013) Esperanto for histones : CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Research, Volume 21 (Number 2). pp. 101-106. doi:10.1007/s10577-013-9347-y ISSN 0967-3849.

Cheeseman, L. P., Harry, Edward, McAinsh, Andrew D., Prior, I. A. and Royle, Stephen J. (2013) Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension. Journal of Cell Science, Volume 126 (Number 9). pp. 2102-2113. doi:10.1242/jcs.124834 ISSN 0021-9533.

2012

Drechsler, Hauke and McAinsh, Andrew D. (2012) Exotic mitotic mechanisms. Open Biology, Vol.2 . Article number 120140. doi:10.1098/rsob.120140 ISSN 2046-2441.

Eskat, Anja, Deng, Wen, Hofmeister, Antje, Rudolphi, Sven, Emmerth, Stephan, Hellwig, Daniela, Ulbricht, Tobias, Döring, Volker, Bancroft, James M., McAinsh, Andrew D., Cardoso, M. Cristina, Meraldi, Patrick, Hoischen, Christian, Leonhardt, Heinrich and Diekmann, Stephan (2012) Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex. PLoS One, Vol.7 (No.9). e44717. doi:10.1371/journal.pone.0044717 ISSN 1932-6203.

Kaseda, Kuniyoshi, McAinsh, Andrew D. and Cross, R. A. (2012) Dual pathway spindle assembly increases both the speed and the fidelity of mitosis. Biology Open, Vol.1 (No.1). pp. 12-18. doi:10.1242/bio.2011012 ISSN 2046-6390.

2011

McAinsh, Andrew D. and Meraldi, Patrick (2011) The CCAN complex : linking centromere specification to control of kinetochore–microtubule dynamics. Seminars in Cell & Developmental Biology, Vol.22 (No.9). pp. 946-952. doi:10.1016/j.semcdb.2011.09.016 ISSN 1084-9521.

Cross, R. A., McAinsh, Andrew D. and Straube, Anne (2011) Mechanochemical cell biology. Seminars in Cell & Developmental Biology, Vol.22 (No.9). pp. 913-915. doi:10.1016/j.semcdb.2011.10.002 ISSN 1084-9521.

Samora, Catarina P., Mogessie, Binyam, Conway, Leslie, Ross, Jennifer L., Straube, Anne and McAinsh, Andrew D. (2011) MAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosis. Nature Cell Biology, Vol.13 (No.9). pp. 1040-1050. doi:10.1038/ncb2297 ISSN 1465-7392.

Vladimirou, Elina, Harry, Edward, Burroughs, Nigel John and McAinsh, Andrew D. (2011) Springs, clutches and motors : driving forward kinetochore mechanism by modelling. Chromosome Research, Volume 19 (Number 3). pp. 409-421. doi:10.1007/s10577-011-9191-x ISSN 0967-3849.

Samora, Catarina P. and McAinsh, Andrew D. (2011) Photoactivatable-GFP-α-tubulin as a tool to study microtubule plus-end turnover in living human cells. In: Straube, Anne, (ed.) Microtubule Dynamics. Methods in Molecular Biology, Vol.777 . Humana Press, pp. 223-233. ISBN 9781617792519

2010

Amaro, Ana C., Samora, Catarina P., Holtackers, Rene, Wang, Enxiu, Kingston, Isabel J., Alonso, M. (Maria), Lampson, Michael, McAinsh, Andrew D. and Meraldi, Patrick (2010) Molecular control of kinetochore-microtubule dynamics and chromosome oscillations. Nature Cell Biology, Vol.12 (No.4). 319-U42. doi:10.1038/ncb2033 ISSN 1465-7392.

Jaqaman, K., King, E. M., Amaro, A. C., Winter, J. R., Dorn, J. F., Elliott, Hunter L., Mchedlishvili, N., McClelland, S. E., Porter, I. M., Posch, M., Toso, A., Danuser, G., McAinsh, Andrew D., Meraldi, P. and Swedlow, Jason (2010) Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases. Journal of Cell Biology, Vol.188 (No.5). pp. 665-679. doi:10.1083/jcb.200909005 ISSN 0021-9525.

2009

Braun, Marcus, Drummond, Douglas R., Cross, R. A. and McAinsh, Andrew D. (2009) The kinesin-14 Klp2 organizes microtubules into parallel bundles by an ATP-dependent sorting mechanism. Nature Cell Biology, Vol.11 (No.6). pp. 724-730. doi:10.1038/ncb1878

Toso, Alberto, Winter, Jennifer R., Garrod, Ainslie J., Amaro, Ana C., Meraldi, Patrick and McAinsh, Andrew D. (2009) Kinetochore-generated pushing forces separate centrosomes during bipolar spindle assembly. Journal of Cell Biology, Vol.184 (No.3). pp. 365-372. doi:10.1083/jcb.200809055 ISSN 0021-9525.

McClelland, Sarah E. and McAinsh, Andrew D. (2009) Hydrodynamic analysis of human kinetochore complexes during mitosis. In: McAinsh, Andrew D., (ed.) Mitosis. Methods in Molecular Biology, Vol.545 . Humana Press, pp. 81-98. ISBN 9781603279925