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Number of items: 38.
2022
Mikhaylina, Alevtina, Ksibe, Amira Z., Wilkinson, Rachael C., Smith, Darbi, Marks, Eleanor, Coverdale, James P. C., Fülöp, Vilmos, Scanlan, David J. and Blindauer, Claudia A. (2022) A single sensor controls large variations in zinc quotas in a marine cyanobacterium. Nature Chemical Biology, 18 . pp. 869-877. doi:10.1038/s41589-022-01051-1 ISSN 1552-4450.
2021
York, Anna, Lloyd, Adrian J., del Genio, Charo I., Shearer, Jonathan, Hinxman, Karen, Fritz, Konstantin, Fülöp, Vilmos, Dowson, Christopher G., Khalid, Syma and Roper, David I. (2021) Structure-based modeling and dynamics of MurM, a Streptococcus pneumoniae penicillin resistance determinant present at the cytoplasmic membrane. Structure, 29 (7). pp. 731-742. doi:10.1016/j.str.2021.03.001 ISSN 0969-2126.
Zhou, Shanshan, Bhukya, Hussain, Malet, Nicolas, Harrison, Peter J. , Rea, Dean, Belousoff, Matthew J., Venugopal, Hariprasad, Sydor, Paulina K., Styles, Kathryn, Song, Lijiang, Cryle, Max J., Alkhalaf, Lona M., Fülöp, Vilmos, Challis, Gregory L. and Corre, Christophe (2021) Molecular basis for control of antibiotic production by a bacterial hormone. Nature, 590 (7846). pp. 463-467. doi:10.1038/s41586-021-03195-x ISSN 0028-0836.
2020
Wilkinson, Rachael C., Rahmanpour, Rahman, Jamshidi, Shirin, Fülöp, Vilmos and Bugg, Timothy D. H. (2020) Extracellular alpha/beta-hydrolase from Paenibacillus species shares structural and functional homology to tobacco salicylic acid binding protein 2. Journal of Structural Biology, 210 (3). 107496. doi:10.1016/j.jsb.2020.107496 ISSN 1047-8477.
2019
Wei, Zhen, Wilkinson, Rachael C., Rashid, Goran M. M., Brown, David, Fülöp, Vilmos and Bugg, Tim (2019) Characterisation of thiamine diphosphate-dependent 4-hydroxybenzoylformate decarboxylase enzymes from Rhodococcus jostii RHA1 and Pseudomonas fluorescens Pf-5 involved in degradation of aryl-C2 lignin degradation fragments. Biochemistry, 58 (52). pp. 5281-5293. doi:10.1021/acs.biochem.9b00177 ISSN 0006-2960.
Kosol, Simone, Gallo, Angelo, Griffiths, Daniel, Valentic, Timothy R., Masschelein, Joleen, Jenner, Matthew, de los Santos, Emmanuel L. C., Manzi, Lucio, Sydor, Paulina K., Rea, Dean, Zhou, Shanshan, Füllöp, Vilmos, Oldham, Neil J., Tsai, Shiou-Chuan, Challis, Gregory L. and Lewandowski, Józef R. (2019) Structural basis for chain release from the enacyloxin polyketide synthase. Nature Chemistry, 11 . 913-923 . doi:10.1038/s41557-019-0335-5 ISSN 1755-4330.
Kosol, Simone, Gallo, Angelo, Griffiths, Daniel, Valentic, Timothy R., Masschelein, Joleen, Jenner, Matthew, de los Santos, Emmanuel L. C., Manzi, Lucio, Sydor, Paulina K., Rea, Dean, Zhou, Shanshan, Fülöp, Vilmos, Oldham, Neil J., Tsai, Shiou-Chuan, Challis, Gregory L. and Lewandowski, Józef R. (2019) Data for Structural basis for chain release from the enacyloxin polyketide synthase. [Dataset]
Alkhalaf, Lona M., Barry, Sarah M., Rea, Dean, Gallo, Angelo, Griffiths, Daniel, Lewandowski, Józef R., Fülöp, Vilmos and Challis, Gregory L. (2019) Binding of distinct substrate conformations enables hydroxylation of remote sties in thaxtomin D by cytochrome P450 TxtC. Journal of the American Chemical Society, 141 (1). pp. 216-222. doi:10.1021/jacs.8b08864 ISSN 0002-7863.
2018
Rashid, Goran M. M., Zhang, Xiaoyang, Wilkinson, Rachael C., Fülöp, Vilmos, Cottyn, Betty, Baumberger, Stéphanie and Bugg, Tim (2018) Sphingobacterium sp. T2 manganese superoxide dismutase catalyses the oxidative demethylation of polymeric lignin via generation of hydroxyl radical. ACS Chemical Biology . doi:10.1021/acschembio.8b00557 ISSN 1554-8929.
Granja-Travez, R. S., Wilkinson, Rachael C., Persinoti, G. F., Squina, F. M., Fülöp, Vilmos and Bugg, Tim (2018) Structural and functional characterisation of multi-copper oxidase CueO from lignin-degrading bacterium Ochrobactrum sp. reveal its activity towards lignin model compounds and lignosulfonate. FEBS Journal, 285 (9). pp. 1684-1700. doi:10.1111/febs.14437 ISSN 1742-4658.
2017
Batson, Sarah, de Chiara, Cesira, Majce, Vita, Lloyd, Adrian J., Gobec, Stanislav, Rea, Dean, Fülöp, Vilmos, Thoroughgood, Christopher W., Simmons, Katie J., Dowson, Christopher G., Fishwick, Colin W. G., de Carvalho, Luiz Pedro S. and Roper, David I. (2017) Inhibition of D-Ala : D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine. Nature Communications, 8 (1). 1939 . doi:10.1038/s41467-017-02118-7 ISSN 2041-1723.
Rea, Dean, Van Elzen, Roos, De Winter, Hans, Van Goethem, Sebastiaan, Landuyt, Bart, Luyten, Walter, Schoofs, Liliane, Van Der Veken, Pieter, Augustyns, Koen, De Meester, Ingrid, Fülöp, Vilmos and Lambeir, Anne-Marie (2017) Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling. European Journal of Medicinal Chemistry, 139 . pp. 482-491. doi:10.1016/j.ejmech.2017.08.024 ISSN 0223-5234.
2016
Rahmanpour, Rahman , Rea, Dean, Jamshidi, Shirin, Fülöp, Vilmos and Bugg, Tim (2016) Structure of thermobifida fusca DyP-type peroxidase and activity towards kraft lignin and lignin model compounds. Archives of Biochemistry and Biophysics, 594 . pp. 54-60. doi:10.1016/j.abb.2016.02.019 ISSN 0003-9861.
2015
Rashid, Goran M. M., Taylor, Charles R. (Charles Robert), Liu, Yangqingxu, Zhang, Xiaoyang, Rea, Dean, Fülöp, Vilmos and Bugg, Tim (2015) Identification of manganese superoxide dismutase from Sphingobacterium sp. T2 as a novel bacterial enzyme for lignin oxidation. ACS chemical biology, 10 (10). pp. 2286-2294. doi:10.1021/acschembio.5b00298 ISSN 1554-8929.
2013
Canning, Peter, Rea, Dean, Morty, Rory E. and Fülöp, Vilmos (2013) Crystal structures of trypanosoma brucei oligopeptidase B broaden the paradigm of catalytic regulation in prolyl oligopeptidase family enzymes. PLoS One, Volume 8 (Number 11). Article number e79349. doi:10.1371/journal.pone.0079349 ISSN 1932-6203.
Marlow, Victoria A., Rea, Dean, Najmudin, Shabir, Wills, Martin and Fülöp, Vilmos (2013) Structure and mechanism of acetolactate decarboxylase. ACS Chemical Biology, 8 (10). pp. 2339-2344. doi:10.1021/cb400429h ISSN 1554-8929.
Noda-Garcia, Lianet, Camacho-Zarco, Aldo R., Medina-Ruíz, Sophía, Gaytán, Paul, Carrillo-Tripp, Mauricio, Fülöp, Vilmos and Barona-Gómez, Francisco (2013) Evolution of substrate specificity in a recipient's enzyme following horizontal gene transfer. Molecular Biology and Evolution, Volume 30 (Number 9). pp. 2024-2034. doi:10.1093/molbev/mst115 ISSN 0737-4038.
Szeltner, Zoltán, Juhász, Tünde, Szamosi, Ilona, Rea, Dean, Fülöp, Vilmos, Módos, Károly, Juliano, Luiz and Polgár, László (2013) The loops facing the active site of prolyl oligopeptidase are crucial components in substrate gating and specificity. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, Vol.1834 (No.1). pp. 98-111. doi:10.1016/j.bbapap.2012.08.012 ISSN 1570-9639.
Ruane, Karen M., Lloyd, Adrian J., Fülöp, Vilmos, Dowson, Christopher G., Barreteau, Hélène, Boniface, Audrey, Dementin, Sébastien, Blanot, Didier, Mengin-Lecreulx, Dominique, Gobec, Stanislav, Dessen, Andréa and Roper, David I. (2013) Specificity determinants for lysine incorporation in staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex. Journal of Biological Chemistry, Volume 288 (Number 46). Article number 33439. doi:10.1074/jbc.M113.508135 ISSN 0021-9258.
2012
Kaszuba, Karol, Róg, Tomasz, Danne, Reinis, Canning, Peter, Fülöp, Vilmos, Juhász, Tünde, Szeltner, Zoltán, St. Pierre, J.-F., García-Horsman, Arturo, Männistö, Pekka T., Karttunen, Mikko, Hokkanen, Jyrki and Bunker, Alex (2012) Molecular dynamics, crystallography and mutagenesis studies on the substrate gating mechanism of prolyl oligopeptidase. Biochimie, Vol.94 (No.6). pp. 1398-1411. doi:10.1016/j.biochi.2012.03.012 ISSN 0300-9084.
Van der Veken, Pieter, Fülöp, Vilmos, Rea, Dean, Gerard, Melanie, Van Elzen, Roos, Joossens, Jurgen, Cheng, Jonathan D., Baekelandt, Veerle, De Meester, Ingrid, Lambeir, Anne-Marie and Augustyns, Koen (2012) P2-SubstitutedN-Acylprolylpyrrolidine Inhibitors of Prolyl Oligopeptidase: Biochemical Evaluation, Binding Mode Determination, and Assessment in a Cellular Model of Synucleinopathy. Journal of Medicinal Chemistry, Vol. 55 (No.22). pp. 9856-9867. doi:10.1021/jm301060g ISSN 0022-2623.
Van der Veken, Pieter, Fülöp, Vilmos, Rea, Dean, Gerard, Melanie, Van Elzen, Roos, Joossens, Jurgen, Cheng, Jonathan D., Baekelandt, Veerle, De Meester, Ingrid, Lambeir, Anne-Marie and Augustyns, Koen (2012) P2-substitutedN-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase : biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy. Journal of Medicinal Chemistry, Vol.55 (No.22). pp. 9856-9867. doi:10.1021/jm301060g ISSN 0022-2623.
2011
Rea, Dean and Fülöp, Vilmos (2011) Prolyl oligopeptidase structure and dynamics. CNS & Neurological Disorders - Drug Targets, Vol.10 (No.3). pp. 306-310. ISSN 1871-5273.
Silver, Barry R., Fülöp, Vilmos and Unwin, Patrick R. (2011) Protein crystallization at oil/water interfaces. New Journal of Chemistry, Vol.35 (No.3). pp. 602-606. doi:10.1039/c0nj00822b ISSN 1144-0546.
2010
Racys, Daurgidas Tomas, Rea, Dean, Fülöp, Vilmos and Wills, Martin (2010) Inhibition of prolyl oligopeptidase with a synthetic unnatural dipeptide. Bioorganic & Medicinal Chemistry, Vol.18 (No.13). pp. 4775-4782. doi:10.1016/j.bmc.2010.05.012 ISSN 0968-0896.
Batson, Sarah, Rea, Dean, Fülöp, Vilmos and Roper, David I. (2010) Crystallization and preliminary X-ray analysis of a D-alanyl-D-alanine ligase (EcDdlB) from Escherichia coli. Journal of Experimental Psychology: Human Perception and Performance, Vol.66 (No.4). pp. 405-408. doi:10.1107/S1744309110003970 ISSN 0096-1523.
Noda-Garcia, Lianet, Camacho-Zarco, Aldo R., Verdel-Aranda, Karina, Wright, H. (Helena), Soberon, Xavier, Fülöp, Vilmos and Barona-Gomez, Francisco (2010) Identification and analysis of residues contained on β → a loops of the dual-substrate (βα)8 phosphoriblosyl isomerase A specific for its phosphoribosyl anthranilate isomerase activity. Protein Science, Vol.19 (No.3). pp. 535-543. doi:10.1002/pro.331 ISSN 0961-8368.
2009
Fülöp, Vilmos, Sam, Katharine A., Ferguson, Stuart J., Ginger, Michael L. and Allen, James W. A. (2009) Structure of a trypanosomatid mitochondrial cytochrome c with heme attached via only one thioether bond and implications for the substrate recognition requirements of heme lyase. FEBS Journal, Vol.276 (No.10). pp. 2822-2832. doi:10.1111/j.1742-4658.2009.07005.x ISSN 1742-464x.
2008
Rea, Dean, Hovington, Rebecca, Rakus, John F., Gerlt, John A., Fülöp, Vilmos, Bugg, Tim and Roper, David I. (2008) Crystal structure and functional assignment of YfaU, a metal ion dependent class II aldolase from Escherichia coli K12. Biochemistry, Vol.47 (No.38). pp. 9955-9965. doi:10.1021/bi800943g ISSN 0006-2960.
Echalier, Aude, Brittain, Thomas, Wright, Joshua, Boycheva, Svetlana, Mortuza, Gulnahar B., Fülöp, Vilmos and Watmough, Nicholas J. (2008) Redox-linked structural changes associated with the formation of a catalytically competent form of the diheme cytochrome c peroxidase from Pseudomonas aeruginosa. Biochemistry, Vol.47 (No.7). pp. 1947-1956. doi:10.1021/bi702064f ISSN 0006-2960.
Wright, H. (Helena), Noda-Garcia, Lianet, Ochoa-Leyva, Adrian, Hodgson, D. A., Fülöp, Vilmos and Barona-Gomez, Francisco (2008) The structure/function relationship of a dual-substrate (beta alpha)(8)-isomerase. Biochemical and Biophysical Research Communications, Volume 365 (Number 1). pp. 16-21. doi:10.1016/j.bbre.2007.10.101 ISSN 0006-291X.
Brittain, Thomas, Boyd, P.D.W., Fülöp, Vilmos and Echalier, Aude (2008) The mechanism of action of di-heme peroxidases: a theoretical study. In: Inorganic biochemistry: research progress. Lancaster: Nova Science, pp. 225-242. ISBN 978-1-604-56708-3
2007
Rea, Dean, Fülöp, Vilmos, Bugg, Tim and Roper, David I. (2007) Structure and mechanism of HpcH : a metal ion dependent class II aldolase from the homoprotocatechuate degradation pathway of Escherichia coli. Journal of Molecular Biology, Vol.373 (No.4). pp. 866-876. doi:10.1016/j.jmb.2007.06.048 ISSN 0022-2836.
Allen, Stuart C. H., Moore, Katherine A. H., Marsden, Catherine J., Fülöp, Vilmos, Moffat, Kevin G., Lord, Mike, Ladds, Graham and Roberts, L. M. (Lynne M.) (2007) The isolation and characterization of temperature-dependent ricin A chain molecules in Saccharomyces cerevisiae. FEBS JOURNAL, 274 (21). pp. 5586-5599. doi:10.1111/j.1742-4658.2007.06080.x ISSN 1742-464X.
Allen, Stuart C. H., Moore, Katherine A. H., Marsden, Catherine J., Fülöp, Vilmos, Moffat, Kevin G., Lord, Mike, Ladds, Graham and Roberts, L. M. (Lynne M.) (2007) The isolation and characterisation of temperature-dependent Ricin A chain molecules in Saccharomyces cerevisiae. FEBS Journal, Vol.274 (No.21). pp. 5586-5599. doi:10.1111/j.1742-4658.2007.06080.x ISSN 1742-464x.
Jamshad, Mohammed, Murrell, J. C. (J. Colin) and Fülöp, Vilmos (2007) Purification and crystallization of the hydroxylase component of the methanesulfonate monooxygenase from Methylosulfonomonas methylovora strain M2. Protein Expression and Purification, Vol.52 (No.2). pp. 472-477. doi:10.1016/j.pep.2006.11.001 ISSN 1046-5928.
Lee, Sarah C., Stoilova-Mcphie, Svetla, Baxter, Laura, Fülöp, Vilmos, Henderson, Janey, Rodger, Alison, Roper, David I., Scott, David J., Smith, Corinne J. and Morgan, J. Alun W. (2007) Structural characterisation of the insecticidal toxin XptA1, reveals a 1.15 MDa tetramer with a cage-like structure. Journal of Molecular Biology, Vol.366 (No.5). pp. 1558-1568. doi:10.1016/j.jmb.2006.12.057 ISSN 0022-2836.
2006
Rea, Dean, Hazell, Carole, Andrews, Norma W., Morty, Rory E. and Fülöp, Vilmos (2006) Expression, purification and preliminary crystallographic analysis of oligopeptidase B from Trypanosoma brucei. Acta Crystallographica Section F - Structural Biology and Crystallization Communications, Vol.62 (Part 8). pp. 808-810. doi:10.1107/S1744309106027874 ISSN 1744-3091.
This list was generated on Fri Mar 29 01:34:07 2024 GMT.