Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC)

Ho, Y. T. Candace, Leng, Daniel J., Ghiringhelli, Francesca, Wilkening, Ina, Bushell, Dexter P., Köstner, Otto, Riva, Elena, Havemann, Judith, Passarella, Daniele and Tosin, Manuela (2017) Novel chemical probes for the investigation of nonribosomal peptide assembly. Chemical Communications, 53 (52). pp. 7088-7091. doi:10.1039/c7cc02427d

Havemann, Judith, Yurkovich, Marie E., Jenkins, Robert, Harringer, Sophia, Tao, Weixin, Wen, Shishi, Sun, Yuhui, Leadlay, P. F. and Tosin, Manuela (2017) Chemical probing of thiotetronate bio-assembly. Chemical Communications, 53 (11). pp. 1912-1915. doi:10.1039/C6CC09933E

Yurkovich, Marie E., Jenkins, Robert, Sun, Yuhui, Tosin, Manuela and Leadlay, P. F. (2017) The polyketide backbone of thiolactomycin is assembled by an unusual iterative polyketide synthase. Chemical Communications, 53 (13). pp. 2182-2185. doi:10.1039/C6CC09934C

Tao, W., Yurkovich, M. E., Wen, S., Lebe, K. E., Samborskyy, M., Liu, Y., Yang, A., Liu, Y., Ju, Y., Deng, Z., Tosin, Manuela, Sun, Y. and Leadlay, P. F. (2016) A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis. Chemical Science, 7 (1). pp. 376-385. doi:10.1039/c5sc03059e

Kage, Hirokazu, Riva, Elena, Parascandolo, James S., Kreutzer, Martin F., Tosin, Manuela and Nett, Markus (2015) Chemical chain termination resolves the timing of ketoreduction in a partially reducing iterative type I polyketide synthase. Organic & Biomolecular Chemistry, 13 (47). pp. 11414-11417. doi:10.1039/c5ob02009c

Riva, Elena, Wilkening, Ina, Gazzola, Silvia, Li, W. M. Ariel, Smith, Luke, Leadlay, P. F. and Tosin, Manuela (2014) Chemical probes for the functionalization of polyketide intermediates. Angewandte Chemie International Edition, 53 (44). pp. 11944-11949. doi:10.1002/anie.201407448

Tosin, Manuela, Smith, L. (Luke) and Leadlay, P. F. (2011) Insights into lasalocid a ring formation by chemical chain termination in vivo. Angewandte Chemie International Edition, Vol.50 (No.50). pp. 11930-11933. doi:10.1002/anie.201106323

Kwan, David H., Tosin, Manuela, Schläger, Nadin, Schulz, F. (Frank) and Leadlay, P. F. (2011) Insights into the stereospecificity of ketoreduction in a modular polyketide synthase. Organic & Biomolecular Chemistry, Vol.9 (No.7). pp. 2053-2056. doi:10.1039/c1ob00022e

Lazos, Orestis, Tosin, Manuela, Slusarczyk, Adrian L., Boakes, Steven, Cortés, Jesus, Sidebottom, Philip J. and Leadlay, P. F. (2010) Biosynthesis of the putative siderophore erythrochelin requires unprecedented crosstalk between separate nonribosomal peptide gene clusters. Chemistry & Biology, Vol.17 (No.2). pp. 160-173. doi:10.1016/j.chembiol.2010.01.011

Sun, Yuhui, Hahn, F., Demydchuk, Yuliya, Chettle, James, Tosin, Manuela, Osada, Hiroyuki and Leadlay, P. F. (2010) In vitro reconstruction of tetronate RK-682 biosynthesis. Nature Chemical Biology, Vol.6 (No.2). pp. 99-101. doi:10.1038/nchembio.285

Tran, Lucky, Broadhurst, R. William, Tosin, Manuela, Cavalli, Andrea and Weissman, Kira J. (2010) Insights into protein-protein and enzyme-substrate interactions in modular polyketide synthases. Chemistry & Biology, Vol.17 (No.7). pp. 705-716. doi:10.1016/j.chembiol.2010.05.017

Tran, Lucky, Tosin, Manuela, Spencer, Jonathan B., Leadlay, P. F. and Weissman, Kira J. (2008) Covalent linkage mediates communication between ACP and TE domains in modular polyketide synthases. Chembiochem, Vol.9 (No.6). pp. 905-915. doi:10.1002/cbic.200700738

COST Action

Ho, Y. T. Candace, Leng, Daniel J., Ghiringhelli, Francesca, Wilkening, Ina, Bushell, Dexter P., Köstner, Otto, Riva, Elena, Havemann, Judith, Passarella, Daniele and Tosin, Manuela (2017) Novel chemical probes for the investigation of nonribosomal peptide assembly. Chemical Communications, 53 (52). pp. 7088-7091. doi:10.1039/c7cc02427d

China. Guo jia ke xue ji shu bu [Ministry of Science and Technology]

Tao, W., Yurkovich, M. E., Wen, S., Lebe, K. E., Samborskyy, M., Liu, Y., Yang, A., Liu, Y., Ju, Y., Deng, Z., Tosin, Manuela, Sun, Y. and Leadlay, P. F. (2016) A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis. Chemical Science, 7 (1). pp. 376-385. doi:10.1039/c5sc03059e

Deutsche Forschungsgemeinschaft (DFG)

Sun, Yuhui, Hahn, F., Demydchuk, Yuliya, Chettle, James, Tosin, Manuela, Osada, Hiroyuki and Leadlay, P. F. (2010) In vitro reconstruction of tetronate RK-682 biosynthesis. Nature Chemical Biology, Vol.6 (No.2). pp. 99-101. doi:10.1038/nchembio.285

ERASMUS (Organization)

Ho, Y. T. Candace, Leng, Daniel J., Ghiringhelli, Francesca, Wilkening, Ina, Bushell, Dexter P., Köstner, Otto, Riva, Elena, Havemann, Judith, Passarella, Daniele and Tosin, Manuela (2017) Novel chemical probes for the investigation of nonribosomal peptide assembly. Chemical Communications, 53 (52). pp. 7088-7091. doi:10.1039/c7cc02427d

Havemann, Judith, Yurkovich, Marie E., Jenkins, Robert, Harringer, Sophia, Tao, Weixin, Wen, Shishi, Sun, Yuhui, Leadlay, P. F. and Tosin, Manuela (2017) Chemical probing of thiotetronate bio-assembly. Chemical Communications, 53 (11). pp. 1912-1915. doi:10.1039/C6CC09933E

Engineering and Physical Sciences Research Council (EPSRC)

Havemann, Judith, Yurkovich, Marie E., Jenkins, Robert, Harringer, Sophia, Tao, Weixin, Wen, Shishi, Sun, Yuhui, Leadlay, P. F. and Tosin, Manuela (2017) Chemical probing of thiotetronate bio-assembly. Chemical Communications, 53 (11). pp. 1912-1915. doi:10.1039/C6CC09933E

Yurkovich, Marie E., Jenkins, Robert, Sun, Yuhui, Tosin, Manuela and Leadlay, P. F. (2017) The polyketide backbone of thiolactomycin is assembled by an unusual iterative polyketide synthase. Chemical Communications, 53 (13). pp. 2182-2185. doi:10.1039/C6CC09934C

Enterprise Ireland

André, Sabine, Velasco-Torrijos, Trinidad, Leyden, Rosaria, Gouin, Sebastien, Tosin, Manuela, Murphy, Paul V. and Gabius, H. J. (2009) Phenylenediamine-based bivalent glycocyclophanes : synthesis and analysis of the influence of scaffold rigidity and ligand spacing on lectin binding in cell systems with different glycomic profiles. Organic & Biomolecular Chemistry, Vol.7 (No.22). pp. 4715-4725. doi:10.1039/b913010a

European Commission (EC)

André, Sabine, Velasco-Torrijos, Trinidad, Leyden, Rosaria, Gouin, Sebastien, Tosin, Manuela, Murphy, Paul V. and Gabius, H. J. (2009) Phenylenediamine-based bivalent glycocyclophanes : synthesis and analysis of the influence of scaffold rigidity and ligand spacing on lectin binding in cell systems with different glycomic profiles. Organic & Biomolecular Chemistry, Vol.7 (No.22). pp. 4715-4725. doi:10.1039/b913010a

GlaxoSmithKline

Lazos, Orestis, Tosin, Manuela, Slusarczyk, Adrian L., Boakes, Steven, Cortés, Jesus, Sidebottom, Philip J. and Leadlay, P. F. (2010) Biosynthesis of the putative siderophore erythrochelin requires unprecedented crosstalk between separate nonribosomal peptide gene clusters. Chemistry & Biology, Vol.17 (No.2). pp. 160-173. doi:10.1016/j.chembiol.2010.01.011

Guo jia zi ran ke xue ji jin wei yuan hui (China) [National Natural Science Foundation of China] (NSFC)

Havemann, Judith, Yurkovich, Marie E., Jenkins, Robert, Harringer, Sophia, Tao, Weixin, Wen, Shishi, Sun, Yuhui, Leadlay, P. F. and Tosin, Manuela (2017) Chemical probing of thiotetronate bio-assembly. Chemical Communications, 53 (11). pp. 1912-1915. doi:10.1039/C6CC09933E

Tao, W., Yurkovich, M. E., Wen, S., Lebe, K. E., Samborskyy, M., Liu, Y., Yang, A., Liu, Y., Ju, Y., Deng, Z., Tosin, Manuela, Sun, Y. and Leadlay, P. F. (2016) A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis. Chemical Science, 7 (1). pp. 376-385. doi:10.1039/c5sc03059e

Herchel Smith Chair of Biochemistry Fund

Tao, W., Yurkovich, M. E., Wen, S., Lebe, K. E., Samborskyy, M., Liu, Y., Yang, A., Liu, Y., Ju, Y., Deng, Z., Tosin, Manuela, Sun, Y. and Leadlay, P. F. (2016) A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis. Chemical Science, 7 (1). pp. 376-385. doi:10.1039/c5sc03059e

Ireland. Higher Education Authority (HEA)

André, Sabine, Velasco-Torrijos, Trinidad, Leyden, Rosaria, Gouin, Sebastien, Tosin, Manuela, Murphy, Paul V. and Gabius, H. J. (2009) Phenylenediamine-based bivalent glycocyclophanes : synthesis and analysis of the influence of scaffold rigidity and ligand spacing on lectin binding in cell systems with different glycomic profiles. Organic & Biomolecular Chemistry, Vol.7 (No.22). pp. 4715-4725. doi:10.1039/b913010a

Irish Research Council for Science, Engineering & Technology (IRCSET)

André, Sabine, Velasco-Torrijos, Trinidad, Leyden, Rosaria, Gouin, Sebastien, Tosin, Manuela, Murphy, Paul V. and Gabius, H. J. (2009) Phenylenediamine-based bivalent glycocyclophanes : synthesis and analysis of the influence of scaffold rigidity and ligand spacing on lectin binding in cell systems with different glycomic profiles. Organic & Biomolecular Chemistry, Vol.7 (No.22). pp. 4715-4725. doi:10.1039/b913010a

Leibniz-Gemeinschaft

Kage, Hirokazu, Riva, Elena, Parascandolo, James S., Kreutzer, Martin F., Tosin, Manuela and Nett, Markus (2015) Chemical chain termination resolves the timing of ketoreduction in a partially reducing iterative type I polyketide synthase. Organic & Biomolecular Chemistry, 13 (47). pp. 11414-11417. doi:10.1039/c5ob02009c

Marie Curie Intra-European Fellowship (IEF)

Ho, Y. T. Candace, Leng, Daniel J., Ghiringhelli, Francesca, Wilkening, Ina, Bushell, Dexter P., Köstner, Otto, Riva, Elena, Havemann, Judith, Passarella, Daniele and Tosin, Manuela (2017) Novel chemical probes for the investigation of nonribosomal peptide assembly. Chemical Communications, 53 (52). pp. 7088-7091. doi:10.1039/c7cc02427d

Riva, Elena, Wilkening, Ina, Gazzola, Silvia, Li, W. M. Ariel, Smith, Luke, Leadlay, P. F. and Tosin, Manuela (2014) Chemical probes for the functionalization of polyketide intermediates. Angewandte Chemie International Edition, 53 (44). pp. 11944-11949. doi:10.1002/anie.201407448

Natural Sciences and Engineering Research Council Canada (NSERC)

Kwan, David H., Tosin, Manuela, Schläger, Nadin, Schulz, F. (Frank) and Leadlay, P. F. (2011) Insights into the stereospecificity of ketoreduction in a modular polyketide synthase. Organic & Biomolecular Chemistry, Vol.9 (No.7). pp. 2053-2056. doi:10.1039/c1ob00022e

Natural Sciences and Engineering Research Council of Canada (NSERC)

Yurkovich, Marie E., Jenkins, Robert, Sun, Yuhui, Tosin, Manuela and Leadlay, P. F. (2017) The polyketide backbone of thiolactomycin is assembled by an unusual iterative polyketide synthase. Chemical Communications, 53 (13). pp. 2182-2185. doi:10.1039/C6CC09934C

Tao, W., Yurkovich, M. E., Wen, S., Lebe, K. E., Samborskyy, M., Liu, Y., Yang, A., Liu, Y., Ju, Y., Deng, Z., Tosin, Manuela, Sun, Y. and Leadlay, P. F. (2016) A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis. Chemical Science, 7 (1). pp. 376-385. doi:10.1039/c5sc03059e

Nuffield Foundation

Lazos, Orestis, Tosin, Manuela, Slusarczyk, Adrian L., Boakes, Steven, Cortés, Jesus, Sidebottom, Philip J. and Leadlay, P. F. (2010) Biosynthesis of the putative siderophore erythrochelin requires unprecedented crosstalk between separate nonribosomal peptide gene clusters. Chemistry & Biology, Vol.17 (No.2). pp. 160-173. doi:10.1016/j.chembiol.2010.01.011

Overseas Research Students Award Scheme (ORSAS)

Kwan, David H., Tosin, Manuela, Schläger, Nadin, Schulz, F. (Frank) and Leadlay, P. F. (2011) Insights into the stereospecificity of ketoreduction in a modular polyketide synthase. Organic & Biomolecular Chemistry, Vol.9 (No.7). pp. 2053-2056. doi:10.1039/c1ob00022e

Seventh Framework Programme (European Commission) (FP7)

Ho, Y. T. Candace, Leng, Daniel J., Ghiringhelli, Francesca, Wilkening, Ina, Bushell, Dexter P., Köstner, Otto, Riva, Elena, Havemann, Judith, Passarella, Daniele and Tosin, Manuela (2017) Novel chemical probes for the investigation of nonribosomal peptide assembly. Chemical Communications, 53 (52). pp. 7088-7091. doi:10.1039/c7cc02427d

Sun, Yuhui, Hahn, F., Demydchuk, Yuliya, Chettle, James, Tosin, Manuela, Osada, Hiroyuki and Leadlay, P. F. (2010) In vitro reconstruction of tetronate RK-682 biosynthesis. Nature Chemical Biology, Vol.6 (No.2). pp. 99-101. doi:10.1038/nchembio.285

Sixth Framework Programme (European Commission) (FP6)

Kwan, David H., Tosin, Manuela, Schläger, Nadin, Schulz, F. (Frank) and Leadlay, P. F. (2011) Insights into the stereospecificity of ketoreduction in a modular polyketide synthase. Organic & Biomolecular Chemistry, Vol.9 (No.7). pp. 2053-2056. doi:10.1039/c1ob00022e

University of Cambridge Herchel Smith Fund

Tosin, Manuela, Demydchuk, Yuliya, Parascandolo, James S., Blasco Per, Covadonga, Leeper, F. J. (Finian J.) and Leadlay, P. F. (2011) In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines. Chemical Communications, Vol.47 (No.12). pp. 3460-3462. doi:10.1039/c0cc05077f

Tosin, Manuela, Smith, L. (Luke) and Leadlay, P. F. (2011) Insights into lasalocid a ring formation by chemical chain termination in vivo. Angewandte Chemie International Edition, Vol.50 (No.50). pp. 11930-11933. doi:10.1002/anie.201106323

Kwan, David H., Tosin, Manuela, Schläger, Nadin, Schulz, F. (Frank) and Leadlay, P. F. (2011) Insights into the stereospecificity of ketoreduction in a modular polyketide synthase. Organic & Biomolecular Chemistry, Vol.9 (No.7). pp. 2053-2056. doi:10.1039/c1ob00022e

Sun, Yuhui, Hahn, F., Demydchuk, Yuliya, Chettle, James, Tosin, Manuela, Osada, Hiroyuki and Leadlay, P. F. (2010) In vitro reconstruction of tetronate RK-682 biosynthesis. Nature Chemical Biology, Vol.6 (No.2). pp. 99-101. doi:10.1038/nchembio.285

University of Cambridge. Cambridge Commonwealth Trusts

Kwan, David H., Tosin, Manuela, Schläger, Nadin, Schulz, F. (Frank) and Leadlay, P. F. (2011) Insights into the stereospecificity of ketoreduction in a modular polyketide synthase. Organic & Biomolecular Chemistry, Vol.9 (No.7). pp. 2053-2056. doi:10.1039/c1ob00022e

University of Warwick Institute of Advanced Study Scholarship

Ho, Y. T. Candace, Leng, Daniel J., Ghiringhelli, Francesca, Wilkening, Ina, Bushell, Dexter P., Köstner, Otto, Riva, Elena, Havemann, Judith, Passarella, Daniele and Tosin, Manuela (2017) Novel chemical probes for the investigation of nonribosomal peptide assembly. Chemical Communications, 53 (52). pp. 7088-7091. doi:10.1039/c7cc02427d

University of Warwick. Institute of Advanced Study (IAS)

Parascandolo, James S., Havemann, Judith, Potter, Helen K., Huang, Fanglu, Riva, Elena, Connolly, Jack, Wilkening, Ina, Song, Lijiang, Leadlay, P. F. and Tosin, Manuela (2016) Insights into 6-methylsalicylic acid bio-assembly by using chemical probes. Angewandte Chemie International Edition, 55 (10). pp. 3463-3467. doi:10.1002/anie.201509038

Riva, Elena, Wilkening, Ina, Gazzola, Silvia, Li, W. M. Ariel, Smith, Luke, Leadlay, P. F. and Tosin, Manuela (2014) Chemical probes for the functionalization of polyketide intermediates. Angewandte Chemie International Edition, 53 (44). pp. 11944-11949. doi:10.1002/anie.201407448

Universität München

André, Sabine, Velasco-Torrijos, Trinidad, Leyden, Rosaria, Gouin, Sebastien, Tosin, Manuela, Murphy, Paul V. and Gabius, H. J. (2009) Phenylenediamine-based bivalent glycocyclophanes : synthesis and analysis of the influence of scaffold rigidity and ligand spacing on lectin binding in cell systems with different glycomic profiles. Organic & Biomolecular Chemistry, Vol.7 (No.22). pp. 4715-4725. doi:10.1039/b913010a

Verein zur Forderung des biologisch-technologischen Fortschritts in der Medizin [Society for the Promotion of Biotechnological Advances in Medicine]

André, Sabine, Velasco-Torrijos, Trinidad, Leyden, Rosaria, Gouin, Sebastien, Tosin, Manuela, Murphy, Paul V. and Gabius, H. J. (2009) Phenylenediamine-based bivalent glycocyclophanes : synthesis and analysis of the influence of scaffold rigidity and ligand spacing on lectin binding in cell systems with different glycomic profiles. Organic & Biomolecular Chemistry, Vol.7 (No.22). pp. 4715-4725. doi:10.1039/b913010a

Wuhan da xue‏ (Nation Wu-han University)

Tao, W., Yurkovich, M. E., Wen, S., Lebe, K. E., Samborskyy, M., Liu, Y., Yang, A., Liu, Y., Ju, Y., Deng, Z., Tosin, Manuela, Sun, Y. and Leadlay, P. F. (2016) A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis. Chemical Science, 7 (1). pp. 376-385. doi:10.1039/c5sc03059e