Journal Article

Kaufmann, Timothy J., Harrison, Paul Michael, Richardson, Magnus J. E., Pinheiro, Teresa J. T. and Wall, Mark J. (2016) Intracellular soluble α-synuclein oligomers reduce pyramidal cell excitability. The Journal of Physiology, 594 (10). 2751-2772 . doi:10.1113/JP271968 ISSN 0022-3751.

Monteiro, João P., Martins, André F., Nunes, Cláudia, Morais, Catarina M., Lúcio, Marlene, Reis, Salette, Pinheiro, Teresa J. T., Geraldes, Carlos F. G. C., Oliveira, Paulo J. and Jurado, Amália S. (2013) A biophysical approach to menadione membrane interactions: Relevance for menadione-induced mitochondria dysfunction and related deleterious/therapeutic effects. Biochimica et Biophysica Acta (BBA) - Biomembranes, Volume 1828 (Number 8). pp. 1899-1908. doi:10.1016/j.bbamem.2013.04.006 ISSN 0005-2736.

Lu, Jin, Stewart, Alan J., Sadler, P. J., Pinheiro, Teresa J. T. and Blindauer, Claudia A. (2012) Allosteric inhibition of cobalt binding to albumin by fatty acids : implications for the detection of myocardial ischemia. Journal of Medicinal Chemistry, Vol.55 (No.9). pp. 4425-4430. doi:10.1021/jm3003137 ISSN 0022-2623.

Lu, Jin, Stewart, Alan J, Sleep, Darrell, Sadler, P. J., Pinheiro, Teresa J. T. and Blindauer, Claudia A. (2012) A molecular mechanism for modulating plasma Zn speciation by fatty acids. Journal of the American Chemical Society, Vol.134 (No.3). pp. 1454-1457. doi:10.1021/ja210496n ISSN 1520-5126.

Monteiro, João P., Martins, André F., Lúcio, Marlene, Reis, Salette, Pinheiro, Teresa J. T., Geraldes, Carlos F. G. C., Oliveira, Paulo J. and Jurado, Amália S. (2011) Nimesulide interaction with membrane model systems : are membrane physical effects involved in nimesulide mitochondrial toxicity? Toxicology in Vitro, Vol.25 (No.6). pp. 1215-1223. doi:10.1016/j.tiv.2011.05.014 ISSN 08872333.

Sanghera, Narinder, Correia, Bruno E. F. S, Correia, Joana R. S., Ludwig, Christian, Agarwal, Sonya, Nakamura, Hironori K., Kuwata, Kazuo, Samain, Eric, Gill, Andrew C., Bonev, Boyan B. and Pinheiro, Teresa J. T. (2011) Deciphering the molecular details for the binding of the prion protein to main ganglioside GM1 of neuronal membranes. Chemistry & Biology, Vol.18 (No.11). pp. 1422-1431. doi:10.1016/j.chembiol.2011.08.016 ISSN 1074-5521.

Hill, Andrew Francis, Graham, James F., Kurian, Dominic, Agarwal, Sonya, Toovey, Lorna, Hunt, Lawrence, Kirby, Louise, Pinheiro, Teresa J. T., Banner, Steven J. and Gill, Andrew C. (2011) Na+/K+-ATPase Is Present in Scrapie-Associated Fibrils, Modulates PrP Misfolding In Vitro and Links PrP Function and Dysfunction. PLoS One, Vol.6 (No.11). Article No.e26813. doi:10.1371/journal.pone.0026813 ISSN 1932-6203.

Gill, Andrew C., Agarwal, Sonya, Pinheiro, Teresa J. T. and Graham, James F. (2010) Structural requirements for efficient prion protein conversion : cofactors may promote a conversion-competent structure for PrPC. Prion, Volume 4 (Number 4). pp. 235-243. doi:10.4161/pri.4.4.13394 ISSN 1933-6896.

Grabenauer, Megan, Wyttenbach, Thomas, Sanghera, Narinder, Slade, Susan E., Pinheiro, Teresa J. T., Scrivens, James H. and Bowers, Michael T. (2010) Conformational stability of Syrian hamster prion protein PrP(90-231). Journal of the American Chemical Society, Vol.132 (No.26). pp. 8816-8818. doi:10.1021/ja100243h ISSN 0002-7863.

Robinson, Philip J. and Pinheiro, Teresa J. T. (2010) Phospholipid composition of membranes directs prions down alternative aggregation pathways. Biophysical Journal, Vol.98 (No.8). pp. 1520-1528. doi:10.1016/j.bpj.2009.12.4304 ISSN 0006-3495.

Graham, James F., Agarwal, Sonya, Kurian, Dominic, Kirby, Louise, Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, Vol.285 (No.13). pp. 9868-9880. doi:10.1074/jbc.M109.093484 ISSN 0021-9258.

Sanghera, Narinder, Swann, Marcus J., Ronan, Gerry and Pinheiro, Teresa J. T. (2009) Insight into early events in the aggregation of the prion protein on lipid membranes. Biochimica et Biophysica Acta (BBA) - Biomembranes, Vol.1788 (No.10). pp. 2245-2251. doi:10.1016/j.bbamem.2009.08.005 ISSN 00052736.

Robinson, Philip J. and Pinheiro, Teresa J. T. (2009) The unfolding of the prion protein sheds light on the mechanisms of prion susceptibility and species barrier. Biochemistry, Vol.48 (No.36). pp. 8551-8558. doi:10.1021/bi901070t ISSN 0006-2960.

Jenkins, David C., Pearson, David S., Harvey, Andrew, Sylvester, Ian D., Geeves, Michael A. and Pinheiro, Teresa J. T. (2009) Rapid folding of the prion protein captured by pressure-jump. European Biophysics Journal, Vol.38 (No.5). pp. 625-635. doi:10.1007/s00249-009-0420-6 ISSN 0175-7571.

Mayerhofer, Peter U., Cook, Jonathan P., Wahlman, Judit, Pinheiro, Teresa J. T., Moore, Katherine A. H., Lord, Mike, Johnson, Arthur E. and Roberts, L. M. (Lynne M.) (2009) Ricin A chain insertion into endoplasmic reticulum membranes is triggered by a temperature increase to 37 degrees C. Journal of Biological Chemistry, Vol.284 (No.15). pp. 10232-10242. doi:10.1074/jbc.M808387200 ISSN 0021-9258.

Lu, Jin, Stewart, Alan J., Sadler, P. J., Pinheiro, Teresa J. T. and Blindauer, Claudia A. (2008) Albumin as a zinc carrier : properties of its high-affinity zinc-binding site. Biochemical Society Transactions, Vol.36 (No.6). pp. 1317-1321. doi:10.1042/BST0361317 ISSN 0300-5127.

Sanghera, Narinder, Wall, Mark J., Venien-Bryan, Catherine and Pinheiro, Teresa J. T. (2008) Globular and pre-fibrillar prion aggregates are toxic to neuronal cells and perturb their electrophysiology. Biochimica et Biophysica Acta - Proteins and Proteomics, Vol.1784 (No.6). pp. 873-881. doi:10.1016/j.bbapap.2008.02.017 ISSN 1570-9639.

Cowan, Richard H., Davies, Rick A. and Pinheiro, Teresa J. T. (2008) A screening system for the identification of refolding conditions for a model protein kinase, p38 alpha. Analytical Biochemistry, Vol.376 (No.1). pp. 25-38. doi:10.1016/j.ab.2008.01.036 ISSN 0003-2697.

Jenkins, David C., Sylvester, Ian D. and Pinheiro, Teresa J. T. (2008) The elusive intermediate on the folding pathway of the prion protein. FEBS Journal, Vol.275 (No.6). pp. 1323-1335. doi:10.1111/j.1742-4658.2008.06293.x ISSN 1742-464x.

Hicks, Matthew R., Rullay, Atvinder K., Pedrido, Rosa, Crout, D. H. G. and Pinheiro, Teresa J. T. (2008) Efficient synthesis of methanesulphonate-derived lipid chains for attachment of proteins to lipid membranes. Synthetic Communications, Volume 38 (Number 21). pp. 3726-3750. doi:10.1080/00397910802213794 ISSN 0039-7911.

Dear, Denise V., Young, Duncan S., Kazlauskaite, Jurate, Meersman, Filip, Oxley, David, Webster, Judith, Pinheiro, Teresa J. T., Gill, Andrew C., Bronstein, Igor and Lowe, Christopher R. (2007) Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro. Biochimica et Biophysica Acta - Proteins and Proteomics, Vol.1774 (No.7). pp. 792-802. doi:10.1016/j.bbapap.2007.05.005 ISSN 1570-9639.

Critchley, Peter, Kazlauskaite, Jurate, Eason, Robert and Pinheiro, Teresa J. T. (2002) Binding of prion proteins to lipid membranes. Biochemical and Biophysical Research Communications, 313 (3). pp. 559-567. doi:10.1016/j.bbrc.2003.12.004 ISSN 0006-291X.

Sanghera, Narinder and Pinheiro, Teresa J. T. (2000) Unfolding and refolding of cytochrome c driven by the interaction with lipid micelles. Protein Science, Vol.9 (No.6). pp. 1194-1202. doi:10.1110/ps.9.6.1194 ISSN 1194-1202.

Conference Item

Hilton, Gillian R., Thalassinos, Konstantinos, Grabenauer, Megan, Sanghera, Narinder, Slade, Susan E., Wyttenbach, Thomas, Robinson, Philip J., Pinheiro, Teresa J. T., Bowers, Michael T. and Scrivens, James H. (2010) Structural analysis of prion proteins by means of drift cell and traveling wave ion mobility mass spectrometry. In: Asilomar Conference on Ion Spectroscopy, Pacific Grove, CA, October 16-20, 2009. Published in: Journal of The American Society for Mass Spectrometry, Vol.21 (No.5). pp. 845-854. doi:10.1016/j.jasms.2010.01.017 ISSN 1044-0305.

Pinheiro, Teresa J. T. (2006) The role of rafts in the fibrillization and aggregation of prions. In: COST Meeting on Protein - Lipid Interactions, Dubrovnik, Croatia, Oct 06-08, 2005. Published in: Chemistry and Physics of Lipids, Vol.141 (No.1-2). pp. 66-71. doi:10.1016/j.chemphyslip.2006.02.022 ISSN 0009-3084.

Journal Item

Robinson, Philip J. and Pinheiro, Teresa J. T. (2010) Growth of prion plaques and spongiform aggregates on lipid membranes. Prion, Vol.4 (No.3). pp. 178-179.