2018

(2018) Adjuvant bevacizumab for melanoma patients at high risk of recurrence : survival analysis of the AVAST-M trial. Annals of Oncology, 29 (8). pp. 1843-1852. doi:10.1093/annonc/mdy229

Lipplaa, Astrid, Fernandes, Ricardo, Marshall, Andrea, Lorigan, Paul, Dunn, Janet A., Myers, Kevin A, Barker, Emily, Newton-Bishop, Julia, Middleton, Mark R. and Corrie, Pippa G. (2018) 25-hydroxyvitamin D serum levels in patients with high risk resected melanoma treated in an adjuvant bevacizumab trial. British Journal of Cancer . doi:10.1038/s41416-018-0179-6 (In Press)

SELECT-D Collaborative Group (Including: Young, Annie M., Marshall, Andrea, Thirlwall, Jenny, Chapman, Oliver, Lokare, Anand, Hill, Catherine, Hale, Danielle, Dunn, Janet A., Lyman, Gary H., Hutchinson, Charles, MacCallum, Peter, Kakkar, Ajay, Hobbs, F. D. Richard, Petrou, Stavros, Dale, Jeremy, Poole, Christopher J., Maraveyas, Anthony and Levine, Mark). (2018) Comparison of an oral factor Xa inhibitor with low molecular weight heparin in cancer patients with venous thromboembolism : results of a randomized trial (SELECT-D). Journal of Clinical Oncology, 36 (20). pp. 2017-2023. doi:10.1200/JCO.2018.78.8034

(2018) An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment. Journal of Clinical Epidemiology, 99 . pp. 75-83. doi:10.1016/j.jclinepi.2018.02.018

Fackrell, D., Marshall, A. (Andrea)‏, Mistry, Pankaj, Dunn, Janet A., De Santis, Maria , Ford, D. and Zarkar, A. (2018) Radical treatment of muscle-invasive bladder cancer-are options equal? Journal of Radiation Oncology, 7 (2). pp. 181-186. doi:10.1007/s13566-018-0347-6

Young, Annie M., Marshall, A. (Andrea)‏, Thirlwall, Jenny, Chapman, O., Lokare, A., Hills, Claire E., Hale, D., Dunn, Janet A., Kakkar, A., Levine, M. and Select-d Collaborative, Group (2018) Anticoagulation therapy in SELECTeD cancer patients at risk of recurrence of venous thromboembolism : results of the 'select-d' Pilot Trial. Thrombosis Research, 164 (Supplement 1). S194. doi:10.1016/j.thromres.2018.02.036

Couper, Keith, Kimani, Peter K., Gale, Chris P., Quinn, Tom., Squire, Iain B., Marshall, A. (Andrea)‏, Black, John J. M., Cooke, Matthew, Ewings, Bob, Long, John and Perkins, Gavin D. (2018) Variation in outcome of hospitalised patients with out-of-hospital cardiac arrest from acute coronary syndrome : a cohort study. Health Services and Delivery Research, 6 (14). doi:10.3310/hsdr06140

Lee, R. J., Gremel, G., Marshall, A. (Andrea)‏, Myers, K. A., Fisher, N., Dunn, Janet A., Dhomen, N., Corrie, P. G., Middleton, M. R., Lorigan, P. and Marais, R. (2018) Circulating tumor DNA predicts survival in patients with resected high risk stage II/III melanoma. Annals of Oncology, 29 (2). pp. 490-496. doi:10.1093/annonc/mdx717

(2018) OPTIMA : A prospective randomized trial to validate the predictive utility and cost-effectiveness of gene expression test-directed chemotherapy decisions in early breast cancer. Cancer Research, 78 (4). Abstract OT1-06-01. doi:10.1158/1538-7445.SABCS17-OT1-06-01

Couper, Keith, Kimani, Peter K., Gale, Chris P., Quinn, Tom, Squire, Iain B., Marshall, A. (Andrea)‏, Black, John J. M., Cooke, Matthew, Ewings, Bob, Long, John and Perkins, Gavin D. (2018) Patient, health service factors and variation in mortality following resuscitated out-of-hospital cardiac arrest in acute coronary syndrome : analysis of the Myocardial Ischaemia National Audit Project. Resuscitation, 124 . pp. 49-57. doi:10.1016/j.resuscitation.2018.01.011

2017

Janowitz, Tobias, Williams, Edward H., Marshall, Andrea, Ainsworth, Nicola, Thomas, Peter B., Sammut, Stephen J., Shepherd, Scott, White, Jeff, Mark, Patrick B., Lynch, Andy G., Jodrell, Duncan I., Tavaré, Simon and Earl, Helena (2017) New model for estimating glomerular filtration rate in patients with cancer. Journal of Clinical Oncology, 35 (24). pp. 2798-2805. doi:10.1200/jco.2017.72.7578

Mistry, Pankaj, Dunn, Janet A. and Marshall, A. (Andrea) (2017) A literature review of applied adaptive design methodology within the field of oncology in randomised controlled trials and a proposed extension to the CONSORT guidelines. BMC Medical Research Methodology, 17 (1). 108. doi:10.1186/s12874-017-0393-6

Dunn, Janet A., Marshall, A. (Andrea)‏, Ramirez, M., Evans, A. and Donnelly, P. (2017) Value of a sister observational cohort alongside a randomised controlled trial with an internal feasibility phase. Trials, 18 (Supplement 1). p. 1. P261 [pp 99]. doi:10.1186/s13063-017-1902-y

Mistry, Pankaj, Dunn, Janet A. and Marshall, A. (Andrea)‏ (2017) A literature review of the use of adaptive design methods in oncology trials. Trials, 18 (Supplement 1). p. 200. P106 [pp 40-41]. doi:10.1186/s13063-017-1902-y

OPTIMA Trial Management Group (Including: Pinder, S. E., Campbell, Amy, Bartlett, J. M. S., Marshall, A. (Andrea)‏, Allen, D., Falzon, M., Dunn, Janet A., Makris, A., Hughes-Davies, L. and Stein, R. C.). (2017) Discrepancies in central review re-testing of patients with ER-positive and HER2-negative breast cancer in the OPTIMA prelim randomised clinical trial. British Journal of Cancer, 116 . 859-863 . doi:10.1038/bjc.2017.28

2016

(2016) Comparing breast cancer multiparameter tests in the OPTIMA Prelim Trial : no test is more equal than the others. Journal of the National Cancer Institute, 108 (9). djw050. doi:10.1093/jnci/djw050

(2016) OPTIMA (Optimal Personalised Treatment of early breast cancer using Multi-parameter Analysis) : A prospective trial to validate the predictive utility and cost-effectiveness of gene expression test-directed chemotherapy decisions. European Journal of Surgical Oncology (EJSO), 42 (5). S9-S10. doi:10.1016/j.ejso.2016.02.048

Young, Annie M., Phillips, Jennifer, Hancocks, N. Helen, Hill, Catherine, Joshi, Neya, Marshall, A. (Andrea)‏, Grumett, Joanne, Dunn, Janet A., Lokare, A. and Chapman, O. (2016) OC-11 - Anticoagulation therapy in selected cancer patients at risk of recurrence of venous thromboembolism. Thrombosis Research, 140 . S172-S173. doi:10.1016/S0049-3848(16)30128-1

Janowitz, Tobias, Thuss-Patience, Peter, Marshall, A. (Andrea)‏, Kang, Jung Hun, Connell, Claire, Cook, Natalie, Dunn, Janet A., Park, Se Hoon and Ford, Hugo (2016) Chemotherapy vs supportive care alone for relapsed gastric, gastroesophageal junction, and oesophageal adenocarcinoma : a meta-analysis of patient-level data. British Journal of Cancer, 114 (4). pp. 381-387. doi:10.1038/bjc.2015.452

Stein, Robert C., Dunn, Janet A., Bartlett, John M. S., Campbell, Amy, Marshall, A. (Andrea)‏, Hall, Peter, Rooshenas, Leila, Morgan, Adrienne, Poole, Christopher, Pinder, Sarah E., Cameron, David A., Stallard, Nigel, Donovan, Jenny L., McCabe, Christopher, Hughes-Davies, Luke and Makris, Andreas (2016) OPTIMA prelim : a randomised feasibility study of personalised care in the treatment of women with early breast cancer. Health Technology Assessment, 20 (10). pp. 1-202. doi:10.3310/hta20100

Malczewski, Agnieszka, Marshall, A. (Andrea)‏, Payne, Miranda J., Mao, Lili, Bafaloukos, Dimitrios, Si, Lu, Pectasides, Dimitrios, Fountzilas, George, Guo, Jun, Gogas, Helen and Middleton, Mark R. (2016) Intravenous high-dose interferon with or without maintenance treatment in melanoma at high risk of recurrence : meta-analysis of three trials. Cancer Medicine, 5 (1). pp. 17-23. doi:10.1002/cam4.563

Meads, David M., Marshall, A. (Andrea)‏, Hulme, Claire T., Dunn, Janet A. and Ford, Hugo E. R. (2016) The cost effectiveness of docetaxel and active symptom control versus active symptom control alone for refractory oesophagogastric adenocarcinoma : economic analysis of the COUGAR-02 trial. PharmacoEconomics, 34 (1). pp. 33-42. doi:10.1007/s40273-015-0324-5

2015

Dunn, Janet A., Marshall, A. (Andrea)‏, Campbell, Amy, Cameron, D., Earl, H., Macpherson, I., Poole, C., Rea, D., Francis, A., Harmer, V., Morgan, A., Stallard, Nigel, Makris, A., Hughes-Davies, L. and Stein, R. (2015) Practicalities of using an adaptive design for decision making within the optima trial : optimal personalized treatment of early breast cancer using multi-parameter tests. Trials, 16 (Supplement 2). P212. doi:10.1186/1745-6215-16-S2-P212

Hall, P., Smith, A., Hulme, C., Vargas-Palacios, A., Dunn, Janet A., Marshall, A. (Andrea)‏, Bartlett, J., Stein, R., Cameron, D. and McCabe, C. (2015) The use of early decision modelling and value of information analysis in an adaptive trial design : results from the OPTIMA preliminary study. Trials, 16 (Supplement 2). O19. doi:10.1186/1745-6215-16-S2-O19

Hiller, Louise, Marshall, A. (Andrea)‏ and Dunn, Janet A. (2015) Assessing violations of the proportional hazards assumption in Cox regression : does the chosen method matter? Trials, 16 (Supplement 2). P134. doi:10.1186/1745-6215-16-S2-P134

(2015) Results of the OPTIMA (Optimal Personalized Treatment of early breast cancer usIng Multi-parameter Analysis) prelim study. European Journal of Cancer Care, 51 (Supplement 3). S268. doi:10.1016/S0959-8049(16)30762-6

Young, Annie M., Phillips, Jessica M., Hancocks, H., Marshall, A. (Andrea)‏, Grumett, J., Dunn, Janet A. and Chapman, Oliver (2015) Anticoagulation therapy in selected cancer patients at risk of recurrence of venous thromboembolism. Journal of Clinical Oncology, 33 (15). p. 1.

Bartlett, J. M. S., Stein, R. C., Bayani, J., Marshall, A. (Andrea)‏, Dunn, Janet A., Campbell, A. F., Cunningham, C., Sobol, M., Hall, P., Rooshenas, L., Morgan, A., Poole, Christopher J., Pinder, S. E., Cameron, D. A., Stallard, Nigel, Donovan, J., McCabe, C., Hughes-Davies, L. and Makris, A. (2015) Comparison of multiparameter tests in the UK OPTIMA-Prelim trial. Cancer Research, 75 (Supplement 9). P4-11-07 . doi:10.1158/1538-7445.SABCS14-P4-11-07

(2015) FKBPL : a marker of good prognosis in breast cancer. Oncotarget, 6 (14). pp. 12209-12223. doi:doi:10.18632/oncotarget.3528

(2015) UK OPTIMA-prelim study demonstrates economic value in more clinical evaluation of multi-parameter prognostic tests in early breast cancer. Cancer Research, 75 (9). p. 2. doi:10.1158/1538-7445.SABCS14-P6-08-11

2014

Abdelaziz, Mahmoud , Marshall, A. (Andrea)‏, Kerr, Amy, Hussain, Khalid, Wotton, Robin, Bishay, Ehab, Kalkat, Maninder, Rajesh, Pala, Steyn, Richard and Naidu, Babu (2014) Erratum : Does the revised cardiac risk index predict cardiac complications following elective lung resection? Journal of Cardiothoracic Surgery, Volume 9 . Article number 182. doi:doi: 10.1186/s13019-014-0182-9

Dunn, Janet A., Donnelly, P. K., Marshall, A. (Andrea)‏, Wilcox, M., Watson, E., Young, Annie M., Balmer, Claire E., Ramirez, M., Hartup, S., Maxwell, A.J. and Evans, A. J. (2014) Follow-up in early breast cancer — a surgical and radiological perceptive. Clinical Oncology, Volume 26 (Number 10). pp. 625-629. doi:10.1016/j.clon.2014.06.015

Lu, Q., Zhuang, Q., Marshall, A. (Andrea)‏, Kesaria, M., Beanland, R. and Krier, A. (2014) InSb quantum dots for the mid-infrared spectral range grown on GaAs substrates using metamorphic InAs buffer layers. Semiconductor Science and Technology, Volume 29 (Number 7). 075011. doi:10.1088/0268-1242/29/7/075011

Young, Annie M., Dunn, Janet A., Chapman, O., Grumett, J., Marshall, A. , Phillips, J. and Lokare, A. (2014) SELECT-D : anticoagulation therapy in selected cancer patients at risk of recurrence of venous thromboembolism. Journal of Clinical Oncology, 32 (15). doi:10.1200/jco.2014.32.15_suppl.tps9661

Young, Annie M., Phillips, J., Marshall, A., Grumett, J., Dunn, Janet A., Lowe, S., Chapman, O. and Lokare, A. (2014) Anticoagulation therapy in selected cancer patients at risk of recurrence of venous thromboembolism. In: 7th ITHIC. Published in: Thrombosis Research, 133 (Supplement 2). S220-S220. ISSN 0049-3848. doi:10.1016/S0049-3848(14)50032-1

(2014) Adjuvant bevacizumab in patients with melanoma at high risk of recurrence (AVAST-M) : preplanned interim results from a multicentre, open-label, randomised controlled phase 3 study. The Lancet Oncology, Volume 15 (Number 6). pp. 620-630. doi:10.1016/S1470-2045(14)70110-X

Wason, J., Marshall, A. (Andrea)‏, Dunn, Janet A., Stein, R. C. and Stallard, Nigel (2014) Adaptive designs for clinical trials assessing biomarker-guided treatment strategies. British Journal of Cancer, Volume 110 (Number 8). pp. 1950-1957. doi:10.1038/bjc.2014.156

Ford, Hugo, Marshall, A. (Andrea), Bridgewater, John A., Janowitz, Tobias, Coxon, Fareeda Y., Wadsley, Jonathan, Mansoor, Wasat, Fyfe, David, Madhusudan, Srinivasan, Middleton, Gary W., Swinson, Daniel, Falk, Stephen, Chau, Ian, Cunningham, David, Kareclas, Paula, Cook, Natalie, Blazeby, Jane M. and Dunn, Janet A. (2014) Docetaxel versus active symptom control for refractory oesophagogastric adenocarcinoma (COUGAR-02) : an open-label, phase 3 randomised controlled trial. The Lancet Oncology, Volume 15 (Number 1). pp. 78-86. doi:10.1016/S1470-2045(13)70549-7

2013

(2013) Adjuvant bevacizumab as treatment for melanoma patients at high risk of recurrence : preplanned interim results for the AVAST-M trial. Journal of Clinical Oncology, 31 (18). doi:10.1200/jco.2013.31.18_suppl.lba9000

(2013) AVAST-M: Adjuvant bevacizumab as treatment for melanoma patients at high risk of recurrence. Journal of Clinical Oncology, 31 (15). doi:10.1200/jco.2013.31.15_suppl.lba9000

Ford, H., Marshall, A. (Andrea)‏, Wadsley, J., Coxon, F. Y., Mansoor, W., Bridgwater, J. A., Madhusudan, S., Falk, S., Middleton, G. W., Swinson, D., Chau, I., Thompson, J., Blazeby, J. M., Cunningham, D., Kareclas, P. and Dunn, Janet A. (2013) COUGAR-02 : a randomized phase 111 study of docetaxel versus active symptom control in advanced esophagogastric adenocarcinoma. Journal of Clinical Oncology, 31 (4). doi:10.1200/jco.2013.31.4_suppl.lba4

2012

Ainsworth, N. L., Marshall, A. (Andrea)‏, Hatcher, H., Whitehead, L., Whitfield, G. A. and Earl, Helena M. (2012) Evaluation of glomerular filtration rate estimation by Cockcroft-Gault, Jelliffe, Wright and Modification of Diet in Renal Disease (MDRD) formulae in oncology patients. Annals of Oncology, Volume 23 (Number 7). pp. 1845-1853. doi:10.1093/annonc/mdr539

Abdelaziz, M., Marshall, A. (Andrea)‏, Hussain, K., Bradley, A., Agostini, P., Bishay, E., Kalkat, M., Steyn, R., Rajesh, P., Dunn, Janet A. and Naidu, B. (2012) Can the thoracoscore and revised cardiac risk index predict outcomes? Lung Cancer, 75 (Supplement 1). S63. doi:10.1016/S0169-5002(12)70193-9

Poole, Christopher J., Marshall, A. (Andrea)‏, Higgins, Helen B., Fletcher, J., Williams, S. J., Lo, N., Fernando, I. N., Osborne, R., Crawford, S. M., Rafii, S., Gill, S. and Dunn, Janet A. (2012) Neo-escape : Neoadjuvant extended sequential chemotherapy with adjuvant postoperative treatment for epithelial nonmucinous advanced inoperable peritoneal malignancy. Journal of Clinical Oncology, 30 (15). p. 1.

Rughani, M. G., Swan, M. C., Adams, T. S., Marshall, A. (Andrea), Asher, R., Cassell, O. C. and Middleton, M. (Mark) (2012) Sentinel node status predicts survival in thick melanomas : the Oxford perspective. European Journal of Surgical Oncology (EJSO), Vol.38 (No.10). pp. 936-942. doi:10.1016/j.ejso.2012.04.011

Bradley, A., Marshall, A. (Andrea), Abdelaziz, M., Hussain, K., Agostini, P., Bishay, E., Kalkat, M., Steyn, R., Rajesh, P., Dunn, Janet A. and Naidu, Babu V. (2012) Thoracoscore fails to predict complications following elective lung resection. European Respiratory Journal, Vol.40 (No.6). pp. 1496-1501. doi:10.1183/09031936.00218111

2011

Marshall, A. (Andrea), Dunn, Janet A., Fletcher, Julie, Higgins, Helen B. and Poole, Christopher (2011) The importance of planning for a seamless transition in an adaptive phase II randomised trial. Trials, Vol.12 (Suppl.1). A7. doi:10.1186/1745-6215-12-S1-A7

2010

Marshall, A. (Andrea), Altman, Douglas G. and Holder, Roger L. (2010) Comparison of imputation methods for handling missing covariate data when fitting a Cox proportional hazards model : a resampling study. BMC Medical Research Methodology, 10 (1). 112. doi:10.1186/1471-2288-10-112

Marshall, A. (Andrea), Altman, Douglas G., Royston, Patrick and Holder, Roger L. (2010) Comparison of techniques for handling missing covariate data within prognostic modelling studies: a simulation study. BMC Medical Research Methodology, Vol.10 (Article 7). doi:10.1186/1471-2288-10-7

2009

Cheah, N. L. C., Lupton, S., Marshall, A. (Andrea), Hartley, A. and Glaholm, J. (2009) Outcome of T1N0M0 squamous cell carcinoma of the larynx treated with short-course radiotherapy to a total dose of 50 Gy in 16 fractions: the Birmingham experience. Clinical Oncology, Vol.21 (No.6). pp. 494-501. doi:10.1016/j.clon.2009.02.008

Marshall, A. (Andrea), Altman, Douglas G., Holder, Roger L. and Royston, Patrick (2009) Combining estimates of interest in prognostic modelling studies after multiple imputation: current practice and guidelines. BMC Medical Research Methodology, Vol.9 (Articl). doi:10.1186/1471-2288-9-57

Marshall, A. (Andrea), Billingham, Lucinda J. and Bryan, Stirling (2009) Can we afford to ignore missing data in cost-effectiveness analyses? European Journal of Health Economics, Vol.10 (No.1). pp. 1-3. doi:10.1007/s10198-008-0129-y

2008

Biswas, S., Wrigley, J., East, C., Hern, A., Marshall, A. (Andrea), Dunn, Janet A., Lorigan, P., Middleton, M. (Mark) and Corrie, P. (2008) A randomised trial evaluating Bevacizumab as adjuvant therapy following resection of AJCC stage IIB, IIC and III cutaneous melanoma : an update. ecancermedicalscience, Vol.2 . p. 108. doi:10.3332/ecancer.2008.108

Biswas, S., East, C., A'Hern, A., Marshall, A. (Andrea), Dunn, Janet A., Lorigan, Paul, Middleton, M. (Mark) and Corrie, P. (2008) Adjuvant bevacizumab is safe treatment for melanoma patients at high risk of recurrence. In: 33rd European Society for Medical Oncology Congress, Stockholm, Sweden, 12-16 Sept 2008. Published in: Annals of Oncology, Vol.19 (Suppl.8). pp. 245-246. ISSN 0923-7534.

Gray, R. G., Rea, Dean, Handley, K., Marshall, A. (Andrea), Pritchard, M. G., Perry, P., Earl, Helena M., Poole, Christopher J., Salman, A. and Lee, M. (2008) aTTom (adjuvant Tamoxifen--To offer more?) : randomized trial of 10 versus 5 years of adjuvant tamoxifen among 6,934 women with estrogen receptor-positive (ER+) or ER untested breast cancer--Preliminary results. In: 2008 ASCO Annual Meeting, Chicago, Illinois, 30 May-3 Jun 2008. Published in: Journal of Clinical Oncology, Vol.26 (No.15S (May 20 Supplement)). p. 513. ISSN 0732-183X.

2007

Burton, Andrea, Billingham, Lucina Jane and Bryan, Stirling (2007) Cost-effectiveness in clinical trials : using multiple imputation to deal with incomplete cost data. Clinical Trials, Vol.4 (No.2). pp. 154-161. doi:10.1177/1740774507076914

Yu, L. -M., Burton, Andrea and Rivero-Arias, Oliver (2007) Evaluation of software for multiple imputation of semi-continuous data. In: Workshop on Multiple Imputation, MRC Biostatist Unit, Cambridge, UK, 12-13 Apr 2005. Published in: Statistical Methods in Medical Research , Volume 16 (Number 3). pp. 243-258. ISSN 0962-2802. doi:10.1177/0962280206074464

2001

Young, Annie M., Marsden, J., Goodman, A., Burton, Andrea and Dunn, Janet A. (2001) Prospective randomized comparison of dacarbazine (DTIC) versus DTIC plus interferon-alpha (IFN-α) in metastatic melanoma. Clinical Oncology, 13 (6). pp. 458-465. doi:10.1053/clon.2001.9314