2018

(2018) Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV) : an open-label randomised controlled phase 3 trial. The Lancet, 393 (10166). pp. 51-60. doi:10.1016/S0140-6736(18)32752-1 ISSN 0140-6736.

Lin, Daniel J., McConkey, Christopher C., Nankivell, Paul, Dunn, Janet A. and Mehanna, Hisham (2018) The impact of institutional clinical trial recruitment versus hospital volume on survival outcomes of patients with head and neck cancer : an analysis of the PET-NECK trial outcomes, UKCRN portfolio, and Hospital Episode Statistics (HES) in England. Oral Oncology, 85 . pp. 40-43. doi:10.1016/j.oraloncology.2018.08.006 ISSN 1368-8375.

2017

Smith, A. F., Hall, P. S., Hulme, C. T., Dunn, Janet A., McConkey, Christopher C., Rahman, J. K., McCabe, C. and Mehanna, H. (2017) Cost-effectiveness analysis of PET-CT-guided management for locally advanced head and neck cancer. European Journal of Cancer, 85 . pp. 6-14. doi:10.1016/j.ejca.2017.07.054 ISSN 0959-8049.

Williamson, Esther, McConkey, Christopher C., Heine, Peter, Dosanjh, Sukhdeep, Williams, Mark and Lamb, S. E. (Sallie E.) (2017) Hand exercises for patients with rheumatoid arthritis : an extended follow-up of the SARAH randomised controlled trial. BMJ Open, 7 (4). e013121. doi:10.1136/bmjopen-2016-013121 ISSN 2044-6055.

Mehanna, H., McConkey, Christopher C., Rahman, J., Wong, W. L., Smith, A. F., Nutting, C., Hartley, A. G. J., Hall, P., Hulme, C., Patel, D., Von Zeidler, S. V., Robinson, M., Sanghera, B., Fresco, L. and Dunn, Janet A. (2017) PET-NECK : a multicentre randomised Phase III non-inferiority trial comparing a positron emission tomography-computerised tomography-guided watch-and-wait policy with planned neck dissection in the management of locally advanced (N2/N3) nodal metastases in patients with squamous cell head and neck cancer. Health Technology Assessment, 21 (17). pp. 1-122. doi:10.3310/hta21170 ISSN 1366-5278.

2016

Smith, A. F., Hall, P. S., Hulme, Charles, McConkey, Christopher C., Dunn, Janet A., Rahman, J. and Mehanna, H. (2016) PET-CT surveillance for advanced head and neck cancer : a cost-effective alternative to planned neck dissection? Annals of Oncology, 27 (Supplement 6). 952PD. doi:10.1093/annonc/mdw376.05

Hartley, A., Fong, C., Sanghera, P., Wong, W. L., McConkey, Christopher C., Rahman, J., Nutting, C. M., Al-Booz, H., Robinson, M., Junor, E., Rizwanullah, M., Dunn, Janet A. and Mehanna, H. (2016) Radiation therapy variation in the Randomized Phase 3 Positron Emission Tomography Neck Study. International Journal of Radiation Oncology Biology Physics, 96 (2). S117. doi:10.1016/j.ijrobp.2016.06.285 ISSN 0360-3016.

2015

Mehanna, H., Wong, W. L., McConkey, Christopher C., Rahman, J. K., Robinson, M., Hartley, A., Nutting, C., Powell, N., Al-Booz, H., Robinson, M., Junor, E., Hulme, C., Smith, A. F., Hall, P. and Dunn, Janet A. (2015) Differences in the quality of life (QoL) and functional outcomes of treatment between HPV associated (HPV plus ) and HPV-patients receiving primary chemoradiotherapy in PET-NECK - a multi-centre randomized phase III controlled trial (RCT) comparing PETCT guided active surveillance with planned neck dissection (ND) for locally advanced (N2/N3) nodal metastases (LANM) in patients with head and neck squamous cell cancer (HNC) treated with primary radical chemoradiotherapy (CRT). European Journal of Cancer, 51 (Supplement 3). S715. doi:10.1016/S0959-8049(16)31936-0

Smith, A. F., Hall, P., Hulme, C., Dunn, Janet A., Rahman, J. K., McConkey, Christopher C. and Mehanna, H. (2015) Is PET-CT guided management for patients with locally advanced head and neck squamous cell cancer (HNSCC) cost-effective? Results from a UK non-inferiority phase III randomized trial. Journal of Clinical Oncology, 33 (15). p. 6010. doi:10.1200/jco.2015.33.15_suppl.6010

Mehanna, H. M., Wong, W. L., McConkey, Christopher C., Rahman, J. K., Robinson, M., Hartley, A. G. J., Nutting, C., Powell, N., Al-Booz, H., Robinson, M., Junor, E., Hulme, C., Smith, A. F., Hall, P. and Dunn, Janet A. (2015) PET-NECK: A multi-centre, randomized, phase III, controlled trial (RCT) comparing PETCT guided active surveillance with planned neck dissection (ND) for locally advanced (N2/N3) nodal metastases (LANM) in patients with head and neck squamous cell cancer (HNSCC) treated with primary radical chemoradiotherapy (CRT). Journal of Clinical Oncology, 33 (15). p. 6009. doi:10.1200/jco.2015.33.15_suppl.6009

Bartlett, J. M. S., McConkey, Christopher C., Munro, A. F., Desmedt, C., Dunn, Janet A., Larsimont, D., O'Malley, F. P., Cameron, D. A., Earl, H., Poole, Christopher J., Shepherd, L. E., Cardoso, F., Jensen, M., Caldas, C., Twelves, C. J., Rea, D. W., Ejlertsen, B., Di Leo, A. and Pritchard, K. I. (2015) Predicting anthracycline benefit : TOP2A and CEP17-not only but also. European Journal of Cancer Care, 33 (15). pp. 1680-1687. doi:10.1200/JCO.2013.54.7869 ISSN 0961-5423.

Williams, Mark A., Williamson, Esther M., Heine, Peter J., Nichols, Vivien P., Glover, Matthew J., Dritsaki, Melina, Adams, Jo, Dosanjh, Sukhdeep, Underwood, Martin, Rahman, Anisur, McConkey, Christopher C., Lord, Joanne and Lamb, S. E. (Sallie E.) (2015) Strengthening and stretching for rheumatoid arthritis of the hand (SARAH). A randomised controlled trial and economic evaluation. Health Technology Assessment, 19 (19). pp. 1-222. doi:10.3310/hta19190 ISSN 1366-5278.

Lamb, S. E. (Sallie E.), Williamson, Esther M., Heine, Peter J., Adams, Jo, Dosanjh, Sukhdeep, Dritsaki, Melina, Glover, Matthew, Lord, Joanne, McConkey, Christopher C., Nichols, Vivien P., Rahman, Anisur, Underwood, Martin and Williams, Mark A. (2015) Exercises to improve function of the rheumatoid hand (SARAH) : a randomised controlled trial. The Lancet, 385 (9966). pp. 421-429. doi:10.1016/S0140-6736(14)60998-3 ISSN 0140-6736.

2013

McCaul, James A., Cymerman, James A., Hislop, Stuart, McConkey, Christopher C., McMahon, Jeremy, Mehanna, Hisham M., Shaw, Richard, Sutton, David N. and Dunn, Janet A. (2013) LIHNCS - Lugol's iodine in head and neck cancer surgery : a multicentre, randomised controlled trial assessing the effectiveness of Lugol’s iodine to assist excision of moderate dysplasia, severe dysplasia and carcinoma in situ at mucosal resection margins of oral and oropharyngeal squamous cell carcinoma : study protocol for a randomised controlled trial. Trials, Volume 14 (Number 1). Article number 310. doi:10.1186/1745-6215-14-310 ISSN 1745-6215.

McCaul, J. A., Pendrill, A., Quantrill, J., Mehanna, H., McConkey, Christopher C. and Dunn, Janet A. (2013) LIHNCS trial (Lugol's iodine in head and neck cancer surgery) : Interim recruitment and data report. Oral Oncology, 49 . S37-S37. doi:10.1016/j.oraloncology.2013.03.088

Nankivell, Paul, Williams, Hazel, Matthews, Paul, Suortamo, Sari, Snead, David R. J., McConkey, Christopher C. and Mehanna, Hisham M. (2013) The binary oral dysplasia grading system : validity testing and suggested improvement. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 115 (Number 1). pp. 87-94. doi:10.1016/j.oooo.2012.10.015 ISSN 2212-4403.

Meade, Sara, McConkey, Christopher C., Sanghera, Paul, Mehanna, Hisham M. and Hartley, Andrew (2013) Revised radiobiological modelling of the contribution of synchronous chemotherapy to the rate of grades 3-4 mucositis in head and neck cancer. Journal of Medical Imaging and Radiation Oncology, Volume 57 (Number 6). pp. 733-738. doi:10.1111/1754-9485.12096 ISSN 1754-9477.

Meade, Sara, Sanghera, Paul, McConkey, Christopher C., Fowler, Jack, Fountzilas, George, Glaholm, John and Hartley, Andrew (2013) Revising the radiobiological model of synchronous chemotherapy in head-and-neck cancer : a new analysis examining reduced weighting of accelerated repopulation. International Journal of Radiation Oncology*Biology*Physics, Volume 86 (Number 1). pp. 157-163. doi:10.1016/j.ijrobp.2012.11.023 ISSN 0360-3016.

Nankivell, Paul C., Williams, H., McConkey, Christopher C., Webster, Keith, High, A., MacLennan, Ken, Senguven, B., Rabbitts, P. and Mehanna, Hisham M. (2013) Tetraspanins CD9 and CD151, epidermal growth factor receptor and cyclooxygenase-2 expression predict malignant progression in oral epithelial dysplasia. British Journal of Cancer, Volume 109 (Number 11). pp. 2864-2874. doi:10.1038/bjc.2013.600 ISSN 0007-0920.

Huijbers, A., Tollenaar, R. A. E. M., v Pelt, G. W., Zeestraten, E. C. M., Dutton, S., McConkey, Christopher C., Domingo, E., Smit, V. T. H. B. M., Midgley, R., Warren, B. F., Johnstone, E. C., Kerr, D. J. and Mesker, W. E. (2013) The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients : validation in the VICTOR trial. Annals of Oncology, Volume 24 (Number 1). pp. 179-185. doi:10.1093/annonc/mds246 ISSN 0923-7534.

2012

Mehanna, Hisham M., Beech, Tom, Nicholson, Tom, El-Hariry, Iman, McConkey, Christopher C., Paleri, Vinidh, Roberts, Sally and Eisele, David W. (2012) Prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer-systematic review and meta-analysis of trends by time and region. Head & Neck, Volume 35 (Number 5). pp. 747-755. doi:10.1002/hed.22015 ISSN 1043-3074.

SARAH Trial Team (Including: Adams, Jo, Bridle, Christopher, Dosanjh, Sukhdeep, Heine, Peter J., Lamb, S. E. (Sallie E.), Lord, J., McConkey, Christopher C., Nichols, Vivien P., Toye, Francine, Underwood, Martin, Williams, Mark A. and Williamson, Esther M.). (2012) Strengthening and stretching for rheumatoid arthritis of the hand (SARAH) : design of a randomised controlled trial of a hand and upper limb exercise intervention - ISRCTN89936343. BMC Musculoskeletal Disorders, Vol.13 (No.1). p. 230. doi:10.1186/1471-2474-13-230 ISSN 1471-2474.

2011

Nankivell, Paul, Weller, Matthew, McConkey, Christopher C., Paleri, Vinidh and Mehanna, Hisham M. (2011) Biomarkers in laryngeal dysplasia : a systematic review. Head & Neck, Vol.33 (No.8). pp. 1170-1176. doi:10.1002/hed.21592 ISSN 10433074.

Hartley, Andrew, Sanghera, Paul, Kazi, W., Mehanna, Hisham M., McConkey, Christopher C., Glaholm, John and Fowler, J. (Jack) (2011) Correlation of currently used radiobiological parameters with local control and acute and late mucosal toxicity in randomised studies of altered fractionation for locally advanced head and neck cancer. Clinical Oncology, Volume 23 (Number 1). pp. 29-33. doi:10.1016/j.clon.2010.08.007 ISSN 0936-6555.

Chan, Anthony K. C., Sanghera, Paul, Choo, B. A., McConkey, Christopher C., Mehanna, Hisham M., Parmar, Satyesh, Pracy, P., Glaholm, John and Hartley, Andrew (2011) Hypofractionated accelerated radiotherapy with concurrent carboplatin for locally advanced squamous cell carcinoma of the head and neck. Clinical Oncology, Volume 23 (Number 1). pp. 34-39. doi:10.1016/j.clon.2010.07.015 ISSN 0936-6555.

2010

Midgley, Rachel S., McConkey, Christopher C., Johnstone, Elaine C., Dunn, Janet A., Smith, Justine L., Grumett, Simon A., Julier, Patrick, Iveson, Claire, Yanagisawa, Yoko, Warren, Bryan, Langman, Michael J. and Kerr, David J. (2010) Phase III randomized trial assessing rofecoxib in the adjuvant setting of colorectal cancer: final results of the VICTOR trial. Journal of Clinical Oncology, Vol.28 (No.30). pp. 4575-4580. doi:10.1200/JCO.2010.29.6244 ISSN 0732-183X.

Weller, M. D., Nankivell, Paul C., McConkey, Christopher C., Paleri, Vinidh and Mehanna, Hisham M. (2010) The risk and interval to malignancy of patients with laryngeal dysplasia ; a systematic review of case series and meta-analysis. Clinical Otolaryngology, Volume 35 (Number 5). pp. 364-372. doi:10.1111/j.1749-4486.2010.02181.x

Bartlett, John M. S., Munro, Alison F., Dunn, Janet A., McConkey, Christopher C., Jordan, S., Twelves, Chris, Cameron, D., Thomas, Jeremy St. J., Campbell, Fiona M., Rea, Daniel W., Provenzano, Elena, Caldas, Carlos, Pharaoh, Paul, Hiller, Louise, Earl, Helena M. and Poole, Christopher (2010) Predictive markers of anthracycline benefit : a prospectively planned analysis of the UK national epirubicin adjuvant trial (NEAT/BR9601). Lancet Oncology, Vol.11 (No.3). pp. 266-274. doi:10.1016/S1470-2045(10)70006-1 ISSN 1470-2045.

Hartley, A., Sanghera, P., Glaholm, J., Mehanna, Hisham M., McConkey, C. and Fowler, J. (2010) Radiobiological modelling of the therapeutic ratio for the addition of synchronous chemotherapy to radiotherapy in locally advanced squamous cell carcinoma of the head and neck. Clinical Oncology, Vol.22 (No.2). pp. 125-130. doi:10.1016/j.clon.2009.10.004 ISSN 0936-6555.

2009

Mehanna, Hisham M., Rattay, Tim, Smith, Joel and McConkey, Christopher C. (2009) Treatment and follow-up of oral dysplasia - a systematic review and meta-analysis. Head & Neck, Vol.31 (No.12). pp. 1600-1609. doi:10.1002/hed.21131 ISSN 10433074.

Hartley, A. G., Sanghera, P., McConkey, Christopher C., Mehanna, Hisham M., Glaholm, J. and Fowler, J. (2009) Modeling the contribution of synchronous chemotherapy to the rate of grade 3 and 4 mucositis in locally advanced squamous cell carcinoma of the head and neck. In: 51st Annual Meeting of the American Society for Radiation Oncology, Chicago, IL, November 01-05, 2009. Published in: International Journal of Radiation: Oncology - Biology - Physics, Vol.75 (No.3 Suppl. S). S394-S394. doi:10.1016/j.ijrobp.2009.05.007 ISSN 0360-3016.

2008

Midgley, Rachel S. J., McConkey, Christopher C., Langman, Michael J., Smith, Justine L., Julier, Patrick, Iveson, Claire, Johnstone, Elaine, Chen, Xiao-he, Dunn, Janet A. and Kerr, David J. (2008) VICTOR : a phase III placebo-controlled trial of rofecoxib in colorectal cancer patients following surgical resection. In: 33rd European Society for Medical Oncology Congress, Stockholm, Sweden, 12-16 Sept 2008. Published in: Annals of Oncology, Vol.19 (No.19 ). p. 1. ISSN 0923-7534.

Isles, M. G., McConkey, Christopher C. and Mehanna, Hisham M. (2008) A systematic review and meta-analysis of the role of positron emission tomography in the follow up of head and neck squamous cell carcinoma following radiotherapy or chemoradiotherapy. Clinical Otolaryngology, Vol.33 (No.3). pp. 210-222. doi:10.1111/j.1749-4486.2008.01688.x

Kerr, David J., Dunn, Janet A., Langman, Michael J., Smith, J. L., Midgley, Rachel S. J., Iveson, Claire and McConkey, Christopher C. (2008) VICTOR : a phase III placebo-controlled trial of rofecoxib in colorectal cancer patients following surgical resection. Journal of Clinical Oncology, Vol.26 (No.15S). p. 4038.

Gray, Richard and McConkey, Christopher C. (2008) Adjuvant chemotherapy for rectal cancer – Authors' reply. Lancet, Vol.371 (No.9623). p. 1503. doi:10.1016/S0140-6736(08)60651-0

Sanghera, P., Wong, D. W. Y., McConkey, Christopher C., Geh, J. I. and Hartley, A. (2008) Chemoradiotherapy for rectal cancer : an updated analysis of factors affecting pathological response. Clinical Oncology, Vol.20 (No.2). pp. 176-183. doi:10.1016/j.clon.2007.11.013 ISSN 0936-6555.

Sanghera, P., Arnfield, John, McConkey, Christopher C. and Hartley, A. (2008) Gap compensation during accelerated hypofractionated radiotherapy in head and neck cancer. Journal of Radiotherapy in Practice, Vol.7 (No.1). pp. 31-38. doi:10.1017/S1460396907006231 ISSN 1460-3969.

Dunn, Janet A., Balmer, Claire E., McConkey, Christopher C., Nutting, Chris, Fisher, Sheila, Wong, Wai Lup, MacLennan, Ken, McCabe, Chris, Hulme, Claire and Mehanna, Hisham M. (2008) PET-NECK : setting up a collaborative clinical trial in a rare disease site. In: Society for Clinical Trials Annual Meeting 2008

2007

QUASAR Collaborative Grp (Including: Gray, Richard, Barnwell, Jennifer, McConkey, Christopher C., Hills, Robert K., Williams, Norman S. and Kerr, David J.). (2007) Adjuvant chemotherapy versus observation in patients with colorectal cancer : a randomised study. Lancet, Vol.370 (No.9604). pp. 2020-2029. doi:10.1016/S0140-6736(07)61866-2 ISSN 0140-6736.

VICTOR Trial Grp (Including: Kerr, David J., Dunn, Janet A., Langman, Michael J., Smith, Justine L., Midgley, Rachel S. J., Stanley, Andrew, Stokes, Joanne C., Julier, Patrick, Iveson, Claire, Duvvuri, Ravi and McConkey, Christopher C.). (2007) Rofecoxib and cardiovascular adverse events in adjuvant treatment of colorectal cancer. New England Journal Of Medicine , Vol.357 (No.4). pp. 360-369. doi:10.1056/NEJMoa071841 ISSN 0028-4793.

Sanghera, Paul, McConkey, Christopher C., Ho, Kean-Fatt, Glaholm, John and Hartley, Andrew (2007) Hypofractionated accelerated radiotherapy with concurrent chemotherapy for locally advanced squamous cell carcinoma of the head and neck. International Journal of Radiation: Oncology - Biology - Physics, Vol.67 (No.5). pp. 1342-1351. doi:10.1016/j.ijrobp.2006.11.015 ISSN 0360-3016.

Sanghera, P., Arnfield, J., McConkey, C. and Hartley, A. (2007) Gap compensation for accelerated hypofractionated schedules. In: UK Radiation Oncology Conference, Edinburgh, March 19-27, 2007. Published in: Clinical Oncology, Vol.19 (No.3). S45-S45. doi:10.1016/j.clon.2007.01.415 ISSN 0936-6555.

Sanghera, P., McConkey, C., Ho, K. F., Glaholm, J. and Hartley, A. (2007) Synchronous chemotherapy and hypofractionated accelerated radiotherapy for locally advanced squamous cell carcinomas of the head and neck. In: International Meeting on Innovative Approaches in Head and Neck Oncology, Barcelona, Spain, February 22-27, 2007. Published in: Radiotherapy and Oncology, Vol.82 (No.S1). S78-S78. doi:10.1016/S0167-8140(07)80212-X ISSN 0167-8140.