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Items where Department is "Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences"
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Number of items: 55.
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Alikhan, Nabil-Fareed, Zhou, Zhemin, Sergeant, Martin J. and Achtman, Mark (2018) A genomic overview of the population structure of Salmonella. PLoS Genetics, 14 (4). e1007261. doi:10.1371/journal.pgen.1007261 ISSN 1553-7390.
Anonye, Blessing (2018) Commentary : Bacteriophage transfer during faecal microbiota transplantation in Clostridium difficile infection is associated with treatment outcome. Frontiers in Cellular and Infection Microbiology, 8 . 104. doi:10.3389/fcimb.2018.00104 ISSN 2235-2988.
Apta-Smith, Michael James, Hernandez Fernaud, Juan Ramon and Bowman, Andrew J. (2018) Evidence for the nuclear import of histones H3.1 & H4 as monomers. EMBO Journal, 37 (19). e98714. doi:10.15252/embj.201798714 ISSN 0261-4189.
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Banerjee, Prithwish (2018) Complicated acute heart failure subsets. Current Heart Failure Reports, 15 (4). pp. 199-200. doi:10.1007/s11897-018-0402-z ISSN 1546-9530.
Barber, T. M. (2018) Is obesity a disease? Expert Reviews Endocrinology and Metabolism, 13 (2). pp. 59-61. doi:10.1080/17446651.2018.1427580 ISSN 1744-6651.
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Chong, Jeronica, Amourda, Christopher and Saunders, Timothy E. (2018) Temporal development of Drosophila embryos is highly robust across a wide temperature range. Journal of The Royal Society Interface, 15 (144). 20180304. doi:10.1098/rsif.2018.0304 ISSN 1742-5689.
Clarke, Nicholas I. and Royle, Stephen J. (2018) FerriTag is a new genetically-encoded inducible tag for correlative light-electron microscopy. Nature Communications, 9 (1). 2604. doi:10.1038/s41467-018-04993-0 ISSN 2041-1723.
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Dimitriadis, Georgios K., Randeva, Harpal S., Saboor Aftab, S. A., Ali, Asad, Hattersley, John G., Pandey, S. B., Grammatopoulos, Dimitris, Valsamakis, Georgios, Jones, T. Hugh and Barber, T. M. (2018) Metabolic phenotype of male obesity-related secondary hypogonadism pre-replacementand post-replacement therapy with intra-muscular testosterone undecanoate therapy. Endocrine, 60 (1). pp. 175-184. doi:10.1007/s12020-017-1516-x ISSN 1355-008X.
Dorati, Federico, Barrett, Glyn, Sanchez-Contreras, Maria, Arseneault, Tanya, JosΓ©, Mateo, Studholme, David, Murillo, JesΓΊs, Caballero, Primitivo, Waterfield, Nicholas R., Arnold, Dawn, Shaw, Liz and Jackson, Robert (2018) Coping with environmental eukaryotes : identification of Pseudomonas syringae genes during the interaction with alternative hosts or predators. Microorganisms, 6 (2). 32. doi:10.3390/microorganisms6020032 ISSN 2076-2607.
Duchi, Diego, Gryte, Kristofer, Robb, Nicole C., Morichaud, Zakia, Sheppard, Carol, Brodolin, Konstantin, Wigneshweraraj, Sivaramesh and Kapanidis, Achillefs N (2018) Conformational heterogeneity and bubble dynamics in single bacterial transcription initiation complexes. Nucleic Acids Research, 46 (2). pp. 677-688. doi:10.1093/nar/gkx1146 ISSN 0305-1048.
Durrieu, Lucia, Kirrmaier, Daniel, Schneidt, Tatjana, Kats, Ilia, Raghavan, Sarada, Hufnagel, Lars, Saunders, Timothy E. and Knop, Michael (2018) Bicoid gradient formation mechanism and dynamics revealed by protein lifetime analysis. Molecular Systems Biology, 14 (9). e8355. doi:10.15252/msb.20188355 ISSN 1744-4292.
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Elder, P. J. D., Ramsden, D. B., Burnett, D., Weickert, Martin O. and Barber, T. (Thomas) (2018) Human amylase gene copy number variation as a determinant of metabolic state. Expert Reviews in Endocrinology and Metabolism, 13 (4). pp. 193-205. doi:10.1080/17446651.2018.1499466 ISSN 1744-6651.
English, Sarah, Steele, Amber, Williams, Alison, Blacklay, Jayne, Sorinola, Olanrewaju, Wernisch, Lorenz and Grammatopoulos, Dimitris (2018) Modelling of psychosocial and lifestyle predictors of peripartum depressive symptoms associated with distinct risk trajectories : a prospective cohort study. Scientific Reports, 8 . 12799 . doi:10.1038/s41598-018-30874-z ISSN 2045-2322.
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Gonçalves Athanasio, Camila , Sommer, Ulf, Viant, Mark R., Chipman, James Kevin and Mirbahai, Leda (2018) Use of 5-azacytidine in a proof-of-concept study to evaluate the impact of pre-natal and post-natal exposures, as well as within generation persistent DNA methylation changes in Daphnia. Ecotoxicology, 27 (5). pp. 556-568. doi:10.1007/s10646-018-1927-3 ISSN 0147-6513.
Gyoergy, Attila, Roblek, Marko, Ratheesh, Aparna, Valoskova, Katarina, Belyaeva, Vera, Wachner, Stephanie, Matsubayashi, Yutaka, SΓ‘nchez-SΓ‘nchez, Besaiz J., Stramer, Brian and Siekhaus, Daria E. (2018) Tools allowing independent visualization and genetic manipulation of Drosophila melanogaster macrophages and surrounding tissues. G3: Genes, Genomes, Genetics, 8 (3). g3.300452.2017. doi:10.1534/g3.117.300452 ISSN 2160-1836.
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Hatano, Tomoyuki, Alioto, Salvatore, Roscioli, Emanuele, Palani, Saravanan, Clarke, Scott T., Kamnev, Anton, Hernandez Fernaud, Juan Ramon, Sivashanmugam, Lavanya, Chapa y Lazo, Bernardo, Jones, Alexandra M., Robinson, Robert C., Sampath, Karuna, Mishima, Masanori, McAinsh, Andrew D., Goode, Bruce L. and Balasubramanian, Mohan K. (2018) Rapid production of pure recombinant actin isoforms in Pichia pastoris. Journal of Cell Science, 131 (8). jcs213827. doi:10.1242/jcs.213827 ISSN 1477-9137.
(2018) Precision and accuracy of single-molecule FRET measurementsβa multi-laboratory benchmark study. Nature Methods, 15 (9). pp. 669-676. doi:10.1038/s41592-018-0085-0 ISSN 1548-7091.
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Innominato, Pasquale F., Komarzynski, Sandra, Palesh, Oxana G., Dallmann, Robert, Bjarnason, Georg A., Giacchetti , Syvie, Ulusakarya , Ayhan, Bouchahda, Mohamed, Haydar, Mazen, Ballesta, Annabelle, KarabouΓ©, Abdoulaye, Wreglesworth, Nicholas I., Spiegel, David and LΓ©vi, Francis A. (2018) Circadian rest-activity rhythm as an objective biomarker of patient-reported outcomes in patients with advanced cancer. Cancer Medicine, 7 (9). pp. 4396-4405. doi:10.1002/cam4.1711 ISSN 2045-7634.
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Jackisch, Laura, Kumsaiyai, W., Moore, Jonathan D., Al-Daghri, N. M., Kyrou, Ioannis, Barber, T. M., Randeva, Harpal S., Kumar, Sudhesh, Tripathi, Gyanendra and McTernan, P. G. (2018) Differential expression of Lp-PLA2 in obesity, type 2 diabetes and the influence of lipids. Diabetologia, 61 . pp. 1155-1166. doi:10.1007/s00125-018-4558-6 ISSN 0012-186X.
Jones, Terence A., Wayte, Sarah C., Reddy, Narendra Lakshmana, Adesanya, Oludolapo, Dimitriadis, Georgios K., Barber, Thomas M. and Hutchinson, Charles E. (2018) Identification of an optimal threshold for detecting human brown adipose tissue using receiver operating characteristic analysis of IDEAL MRI fat fraction maps. Magnetic Resonance Imaging, 51 . pp. 61-68. doi:10.1016/j.mri.2018.04.013 ISSN 0730-725X.
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Komarzynski, Sandra, Huang, Qi, Innominato, Pasquale F., Maurice, Monique, Arbaud, Alexandre, Beau, Jacques, Bouchahda, Mohamed, Ulusakarya, Ayhan, Beaumatin, Nicolas, Breda, Gabrièle, FinkenstÀdt, BÀrbel and Lévi, Francis A. (2018) Relevance of a mobile internet platform for capturing inter- and intrasubject variabilities in circadian coordination during daily routine : pilot study. Journal of Medical Internet Research, 20 (6). e204. doi:10.2196/jmir.9779 ISSN 1438-8871.
Kyritsi, Eleni Magdalini, Dimitriadis, Georgios K., Angelousi, Anna, Mehta, Hiten, Shad, Amjad, Mytilinaiou, Maria, Kaltsas, Gregory and Randeva, Harpal S. (2018) The value of PRL in predicting prolactinΞΏma in hyperprolactinemic PCOS. European Journal of Clinical Investigation, 48 (7). e12961. doi:10.1111/eci.12961 ISSN 1365-2362.
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Legrand, Catherine, Ahmed, Usman, Anwar, Attia, Rajpoot, Kashif, Pasha, Sabah, Lambert, CΓ©cile, Davidson, Rose K., Clark , Ian M., Thornalley, Paul J., Henrotin, Yves and Rabbani, Naila (2018) Glycation marker glucosepane increases with the progression of osteoarthritis and correlates with morphological and functional changes of cartilage in vivo. Arthritis Research & Therapy, 20 . 131. doi:10.1186/s13075-018-1636-6
Lim, Tzer Chyn, Hatano, Tomoyuki, Kamnev, Anton, Balasubramanian, Mohan K. and Chew, Ting Gang (2018) Equatorial assembly of the cell-division actomyosin ring in the absence of cytokinetic spatial cues. Current Biology, 28 (6). pp. 955-962. e3. doi:10.1016/j.cub.2018.01.088 ISSN 1879-0445.
Lo, Angela Kwok-Fung, Lung, Raymond Wai-Ming, Dawson, Christopher W., Young, Lawrence S., Ko, Chuen-Wai, Yeung, Walter Wai, Kang, Wei, To, Ka-Fai and Lo, Kwok-Wai (2018) Activation of sterol regulatory element-binding protein 1 (SREBP1)-mediated lipogenesis by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) promotes cell proliferation and progression of nasopharyngeal carcinoma. Journal of Pathology, 246 (2). pp. 180-190. doi:10.1002/path.5130 ISSN 0022-3417.
Lung, Raymond W-M., Hau, Pok-Man, Yu, Ken H-O., Yip, Kevin Y., Tong, Joanna H-M., Chak, Wing-Po, Chan, Anthony W-H., Lam, Ka-Hei, Lo, Angela Kwok-Fung, Tin, Edith K-Y., Chau, Shuk-Ling, Pang, Jesse C-S., Kwan, Johnny S-H., Busson, Pierre, Young, Lawrence S., Yap, Lee-Fah, Tsao, Sai-Wah, To, Ka-Fai and Lo, Kwok-Wai (2018) EBV-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma. The Journal of Pathology, 244 (4). pp. 394-407. doi:10.1002/path.5018 ISSN 0022-3417.
Lutton, E. Josiah, Lammers, Wim J. E. P., James, Sean G., Berg, Hugo van den and Blanks, Andrew M. (2018) Identification of uterine pacemaker regions at the myometrial-placental interface in the rat. The Journal of Physiology, 596 (14). pp. 2841-2852. doi:10.1113/JP275688 ISSN 0022-3751.
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MarΓn-LΓ³pez, Manuel Alejandro, Planas-Iglesias, Joan, Aguirre-Plans, Joaquim, Bonet, Jaume, Garcia-Garcia, Javier, Fernandez-Fuentes, Narcis and Oliva, Baldo (2018) On the mechanisms of protein interactions : predicting their affinity from unbound tertiary structures. Bioinformatics, 34 (4). pp. 592-598. doi:10.1093/bioinformatics/btx616 ISSN 1367-4803.
McHugh, Toni, Drechsler, Hauke, McAinsh, Andrew D., Carter, Nicholas J. and Cross, R. A. (2018) Kif15 functions as an active mechanical ratchet. Molecular Biology of the Cell, 29 (4). pp. 1743-1752. doi:10.1091/mbc.E18-03-0151 ISSN 1059-1524.
Millership, Steven J., Tunster, Simon J., Pette, Mathew Van de, Choudhury, Agharul I., Irvine, Elaine E., Christian, Mark, Fisher, Amanda G., John, Rosalind M., Scott, James and Withers, Dominic J. (2018) Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv mice. Molecular Metabolism, 18 . pp. 97-106. doi:10.1016/j.molmet.2018.09.001 ISSN 2212-8778.
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Nasiri-Ansari, Narjes, Dimitriadis, Georgios K., Agrogiannis, Georgios, Perrea, Despoina, Kostakis, Ioannis D., Kaltsas, Gregory, Papavassiliou, Athanasios G., Randeva, Harpal S. and Kassi, Eva (2018) Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice. Cardiovascular Diabetology, 17 . 106. doi:10.1186/s12933-018-0749-1 ISSN 1475-2840.
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Palani, Saravanan, Srinivasan, Rajagopalan, Zambon, Paola, Kamnev, Anton, Gayathri, Pananghat and Balasubramanian, Mohan K. (2018) Steric hindrance in the upper 50 kDa domain of the motor Myo2p leads to cytokinesis defects in fission yeast. Journal of Cell Science, 131 (1). jcs205625. doi:10.1242/jcs.205625 ISSN 1477-9137.
Patel, Vanlata H., Karteris, Emmanouil, Chen, Jing, Kyrou, Ioannis, Mattu, Harman, Dimitriadis, Georgios K., Rodrigo, Glenn, Antoniades, Charalambos, Antonopoulos, Alexios, Tan, Bee K., Hillhouse, Edward W., Ng, Andre and Randeva, Harpal S. (2018) Functional cardiac orexin receptors : role of orexin-B/orexin 2 receptor in myocardial protection. Clinical Science, 132 (24). pp. 2547-2564. doi:10.1042/CS20180150 ISSN 0143-5221.
Pearce, Madison E., Alikhan, Nabil-Fareed, Dallman, Timothy J., Zhou, Zhemin, Grant, Kathie and Maiden, Martin C. J. (2018) Comparative analysis of core genome MLST and SNP typing within a European Salmonella serovar Enteritidis outbreak. International Journal of Food Microbiology, 274 . pp. 1-11. doi:10.1016/j.ijfoodmicro.2018.02.023 ISSN 1879-3460.
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Rabbani, Naila and Thornalley, Paul J. (2018) Advanced glycation endproducts in the pathogenesis of chronic kidney disease. Kidney International, 93 (4). pp. 803-813. doi:10.1016/j.kint.2017.11.034 ISSN 0085-2538.
Rabbani, Naila, Xue, Mingzhan, Weickert, Martin O. and Thornalley, Paul J. (2018) Multiple roles of glyoxalase 1-mediated suppression of methylglyoxal glycation in cancer biologyβinvolvement in tumour suppression, tumour growth, multidrug resistance and target for chemotherapy. Seminars in Cancer Biology, 49 . pp. 83-93. doi:10.1016/j.semcancer.2017.05.006 ISSN 1044-579X.
Ratheesh, Aparna, Biebl, Julia, Vesela, Jana, Smutny, Michael, Papusheva, Ekaterina, Krens, S. F. Gabriel, Kaufmann, Walter, Gyoergy, Attila, Casano, Alessandra Maria and Siekhaus, Daria E. (2018) Drosophila TNF modulates tissue tension in the embryo to facilitate macrophage invasive migration. Developmental Cell, 45 (3). pp. 331-346. e7. doi:10.1016/j.devcel.2018.04.002 ISSN 1534-5807.
Roper, Joanna C., Al Wattar, Bassel H., Silva, Adikarige Haritha Dulanka, Samarasekera, Shanika, Flint, Graham and Pirie, Alex M. (2018) Management and birth outcomes of pregnant women with Chiari malformations : a 14 years retrospective case series. European Journal of Obstetrics & Gynecology and Reproductive Biology, 230 . pp. 1-5. doi:10.1016/j.ejogrb.2018.09.006 ISSN 0301-2115.
Roth, Daniel, Fitton, Benjamin, Chmel, Nikola Paul, Wasiluk, Natalia and Straube, Anne (2018) Spatial positioning of EB family proteins at microtubule tips involves distinct nucleotide-dependent binding properties. Journal of Cell Science, 132 . jcs219550. doi:10.1242/jcs.219550 ISSN 0021-9533.
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Schilperoort, Maaike, van Dam, Andrea D., Hoeke, Geerte, Shabalina, Irina G., Okolo, Anthony, Hanyaloglu, Aylin C., Dib, Lea H., Mol, Isabel M., Caengprasath, Natarin, Chan, Yi-Wah, Damak, Sami, Miller, Anne Reifel, Coskun, Tamer, Shimpukade, Bharat, Ulven, Trond, Kooijman, Sander, Rensen, Patrick C. N. and Christian, Mark (2018) The GPR120 agonist TUGβ891 promotes metabolic health by stimulating mitochondrial respiration in brown fat. EMBO Molecular Medicine, 10 (3). e8047. doi:10.15252/emmm.201708047 ISSN 1757-4676.
Schmitt, Karen, Grimm, Amandine, Dallmann, Robert, Oettinghaus, Bjoern, Restelli, Lisa Michelle, Witzig, Melissa, Ishihara, Naotada, Mihara, Katsuyoshi, Ripperger, JΓΌrgen A., Albrecht, Urs, Frank, Stephan, Brown, Steven A. and Eckert, Anne (2018) Circadian control of DRP1 activity regulates mitochondrial dynamics and bioenergetics. Cell Metabolism, 27 (3). pp. 657-666. doi:10.1016/j.cmet.2018.01.011 ISSN 1550-4131.
Shah, Neha, Abraham, Jenny, Goodwin, Wendy, Kahal, Hassan, Menon, Vinod, Lam, F. T. and Barber, Thomas M. (2018) Effective implementation of peri-operative local guidelines for metabolic surgery in patients with diabetes mellitus in a tier 4 setting demonstrate improved work efficiency and resource allocation. Obesity Surgery, 28 (10). pp. 3342-3347. doi:10.1007/s11695-018-3389-3 ISSN 0960-8923.
(2018) Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease. Proteome Science, 16 (1). 4. doi:10.1186/s12953-018-0131-y ISSN 1477-5956.
Stefanini, Irene (2018) Yeast-insect associations : it takes guts. Yeast, 35 (4). pp. 315-330. doi:10.1002/yea.3309 ISSN 0749-503X.
Stefanini, Irene, Rizzetto, Lisa, Rivero, Damariz, Carbonell, Silvia, Gut, Marta, Heath, Simon, Gut, Ivo G, Trabocchi, Andrea, Guarna, Antonio, Ben Ghazzi, Nagwa, Bowyer, Paul, Kapushesky, Misha and Cavalieri, Duccio (2018) Deciphering the mechanism of action of 089, a compound impairing the fungal cell cycle. Scientific Reports, 8 (1). 5964. doi:10.1038/s41598-018-24341-y ISSN 2045-2322.
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Torrino, StΓ©phanie, Shen, Wei-Wei, Blouin, CΓ©dric M., Mani, Satish Kailasam, Viaris de Lesegno, Christine, Bost, Pierre, Grassart, Alexandre, KΓΆster, Darius, Valades-Cruz, Cesar Augusto, Chambon, ValΓ©rie, Johannes, Ludger, Pierobon, Paolo, Soumelis, Vassili, Coirault, Catherine, Vassilopoulos, StΓ©phane and Lamaze, Christophe (2018) EHD2 is a mechanotransducer connecting caveolae dynamics with gene transcription. The Journal of Cell Biology . jcb.201801122. doi:10.1083/jcb.201801122 ISSN 0021-9525.
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Vrljicak, Pavle, Lucas, Emma S., Lansdowne, Lauren, Lucciola, Raffaella, Muter, Joanne, Dyer, Nigel P., Brosens, Jan J. and Ott, Sascha (2018) Analysis of chromatin accessibility in decidualizing human endometrial stromal cells. FASEB Journal, 32 (5). 2467-2477 . doi:10.1096/fj.201701098R ISSN 0892-6638.
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Wang, Chunmei, Wang, Qinqin, Ji, Bingyuan, Pan, Yanyou, Xu, Chao, Cheng, Baohua, Bai, Bo and Chen, Jing (2018) The orexin/receptor system : molecular mechanism and therapeutic potential for neurological diseases. Frontiers in Molecular Neuroscience, 11 . p. 220. doi:10.3389/fnmol.2018.00220 ISSN 1662-5099.
Widlak, Monika, Neal, Matthew, Daulton, Emma, Thomas, Claire L., Tomkins, Claudia, Singh, Baljit, Harmston, Christopher , Wicaksono, Alfian, Evans, Charles, Smith, Steve, Savage, Richard S., Covington, James A. and Arasaradnam, Ramesh P. (2018) Risk stratification of symptomatic patients suspected of colorectal cancer using faecal and urinary markers. Colorectal Disease, 20 (12). O335-O342. doi:10.1111/codi.14431 ISSN 1462-8910.
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Xue, Qingjie, Bai, Bo, Ji, Bingyuan, Chen, Xiaoyu, Wang, Chunmei, Wang, Peixiang, Yang, Chunqing, Zhang, Rumin, Jiang, Yunlu, Pan, Yanyou, Cheng, Baohua and Chen, Jing (2018) Ghrelin through GHSR1a and OX1R heterodimers reveals a GΞ±sβcAMP-cAMP response element binding protein signaling pathway in vitro. Frontiers in Molecular Neuroscience, 11 . 245. doi:10.3389/fnmol.2018.00245 ISSN 1662-5099.
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Yin, Jianmin, Lee, Raymond, Ono, Yosuke, Ingham, Philip W. and Saunders, Timothy E. (2018) Spatiotemporal coordination of FGF and Shh signaling underlies the specification of myoblasts in the zebrafish embryo. Developmental Cell, 46 (6). 735-750.e4. doi:10.1016/j.devcel.2018.08.024 ISSN 1534-5807.
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Zaucker, Andreas, Nagorska, Agnieszka, Kumari, Pooja, Hecker, Nikolai, Wang, Ying, Huang, Sizhou, Cooper, Ledean, Sivashanmugam, Lavanya, Vijaykumar, Shruthi, Brosens, Jan J., Gorodkin, Jan and Sampath, Karuna (2018) Translational co-regulation of a ligand and inhibitor by a conserved RNA element. Nucleic Acids Research, 46 (1). pp. 104-119. doi:10.1093/nar/gkx938 ISSN 0305-1048.
Zhou, Zhemin, Luhmann, Nina, Alikhan, Nabil-Fareed, Quince, Christopher and Achtman, Mark (2018) Accurate reconstruction of microbial strains from metagenomic sequencing using representative reference genomes. In: RECOMB 2018 : International Conference on Research in Computational Molecular Biology, Paris, 21-24 Apr 2018. Published in: Lecture Notes in Computer Science, 10812 pp. 225-240. ISBN 9783319899299. doi:10.1007/978-3-319-89929-9_15 ISSN 0302-9743.
Zhou, Zhemin, LundstrΓΈm, Inge, Tran-Dien, Alicia, DuchΓͺne, SebastiΓ‘n, Alikhan, Nabil-Fareed, Sergeant, Martin J., Langridge, Gemma, Fotakis, Anna K., Nair, Satheesh, StenΓΈien, Hans K., Hamre, Stian S., Casjens, Sherwood, Christophersen, Axel, Quince, Christopher , Thomson, Nicholas R., Weill, FranΓ§ois-Xavier, Ho, Simon Y. W., Gilbert, M. Thomas P. and Achtman, Mark (2018) Pan-genome analysis of ancient and modern Salmonella enterica demonstrates genomic stability of the invasive Para C lineage for millennia. Current Biology, 28 (15). pp. 2420-2428. doi:10.1016/j.cub.2018.05.058 ISSN 0960-9822.
Zwetsloot, Alexander, Tut, Gokhan and Straube, Anne (2018) Measuring microtubule dynamics. Essays in Biochemistry . EBC20180035. doi:10.1042/EBC20180035 ISSN 0071-1365.