Journal Article

Adlan, Ahmed M, Arujuna, Aruna, Dowd, Rory, Hayat, Sajad, Panikker, Sandeep, Foster, Will, Yusuf, Shamil, Umar, Fraz, Lellouche, Nicolas, Osman, Faizel and Dhanjal, Tarvinder (2019) Long-term follow-up of normal and structural heart ventricular tachycardia catheter ablation : real-world experience from a UK tertiary centre. Open Heart, 6 (2). e000996. doi:10.1136/openhrt-2018-000996

Al Wattar, Bassel H. (2019) Evaluating the value of intrapartum fetal scalp blood sampling to predict adverse neonatal outcomes : a UK multicentre observational study. European Journal of Obstetrics & Gynecology and Reproductive Biology, 240 . pp. 62-67. doi:10.1016/j.ejogrb.2019.06.012

Al Wattar, Bassel H., Dodds, Julie, Placzek, Anna, Beresford, Lee, Spyreli, Eleni, Moore, Amanda, Gonzalez-Carreras, Francisco J., Austin, Frances, Murugesu, Nilaani, Roseboom, Tessa J., Bes-Rastrollo, Maira, Hitman, Graham A., Hooper, Richard, Khan, Khalid S. and Thangaratinam, Shakila (2019) Mediterranean-style diet in pregnant women with metabolic risk factors (ESTEEM) : a pragmatic multicentre randomised trial. PLoS Medicine, 16 (7). e1002857. doi:10.1371/journal.pmed.1002857

Al Wattar, Bassel H., Murugesu, Nilaani, Tobias, Aurelio, Zamora, Javier and Khan, Khalid S. (2019) Management of first-trimester miscarriage : a systematic review and network meta-analysis. Human Reproduction Update, 25 (3). pp. 362-374. doi:10.1093/humupd/dmz002

Anonye, Blessing O., Hassall, Jack, Patient, Jamie, Detamornrat, Usanee, Aladdad, Afnan M., Schüller, Stephanie, Rose, Felicity R. A. J. and Unnikrishnan, Meera (2019) Probing Clostridium difficile infection in complex human gut cellular models. Frontiers in Microbiology, 10 . 879. doi:10.3389/fmicb.2019.00879

Barber, Thomas M., Hanson, Petra, Weickert, Martin O. and Franks, Stephen (2019) Obesity and polycystic ovary syndrome : implications for pathogenesis and novel management strategies. Clinical Medicine Insights: Reproductive Health, 13 . doi:10.1177/1179558119874042

Capalbo, Luisa, Bassi, Zuni I., Geymonat, Marco, Todesca, Sofia, Copoiu, Liviu, Enright, Anton J., Callaini, Giuliano, Riparbelli, Maria Giovanna, Yu, Lu, Choudhary, Jyoti S., Ferrero, Enrico, Wheatley, Sally, Douglas, Max E., Mishima, Masanori and D'Avino, Pier Paolo (2019) The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis. Nature Communications, 10 (1). 4513. doi:10.1038/s41467-019-12507-9

Chawla, Amit, Paraoan, Vlad, Rabiu, Rasheed, Clark, Tamsyn, Powell, Sam, Grammatopoulos, Dimitris, Armitage, Charlotte, Penedo, Ana, Havard, Alwyn, Metcalfe, Andrew J., Barlow, Timothy and Khatri, Chetan (2019) Determining the stress biomarker profile in patients undergoing total knee replacement and the relationship with outcome at 12 months. The Knee, 26 (6). pp. 1379-1385. doi:10.1016/j.knee.2019.08.010

Cheffings, Thomas H., Burroughs, Nigel John and Balasubramanian, Mohan K. (2019) Actin turnover ensures uniform tension distribution during cytokinetic actomyosin ring contraction. Molecular Biology of the Cell, 30 (8). pp. 933-1049. doi:10.1091/mbc.E18-08-0511

Chen, Lihong, Song, Nan, Liu, Bo, Zhang, Nan, Alikhan, Nabil-Fareed, Zhou, Zhemin, Zhou, Yanyan, Zhou, Siyu, Zheng, Dandan, Chen, Mingxing, Hapeshi, Alexia, Healey, Joseph R. J., Waterfield, Nicholas R., Yang, Jian and Yang, Guowei (2019) Genome-wide identification and characterization of a superfamily of bacterial extracellular contractile injection systems. Cell Reports, 29 (2). 511-521.e2. doi:10.1016/j.celrep.2019.08.096

Connahs, Heidi, Tlili, Sham, van Creij, Jelle, Loo, Tricia Y. J., Banerjee, Tirtha Das, Saunders, Timothy E. and Monteiro, Antónia (2019) Activation of butterfly eyespots by Distal-less is consistent with a reaction-diffusion process. Development, 146 (9). dev169367. doi:10.1242/dev.169367

Cook, Alexander B., Peltier, Raoul, Zhang, Junliang, Gurnani, Pratik, Tanaka, Joji, Burns, James A., Dallmann, Robert, Hartlieb, Matthias and Perrier, Sébastien (2019) Hyperbranched poly(ethylenimine-co-oxazoline) by thiol–yne chemistry for non-viral gene delivery : investigating the role of polymer architecture. Polymer Chemistry, 10 (10). pp. 1202-1212. doi:10.1039/C8PY01648H

(2019) A randomized trial of progesterone in women with bleeding in early pregnancy. New England Journal of Medicine, 380 (19). pp. 1815-1824. doi:10.1056/NEJMoa1813730

Daskalakisa, Kosmas, Chatzelis, Eleftherios, Tsolib, Marina, Papadopoulou, Nectaria, Dimitriadis, Georgios K., Tsolakise, Apostolos V. and Kaltsas, Gregory (2019) Endocrine paraneoplastic syndromes in patients with neuroendocrine neoplasms. Endocrine, 64 . pp. 384-392. doi:10.1007/s12020-018-1773-3

Davies, Melanie J., Russell-Jones, David, Barber, Thomas M., Lavalle-Gonzalez, Fernando J., Galstyan, Gagik R., Zhu, Dhalong, Baxter, Mike, Dessapt-Baradez, Cecile and McCrimmon, Rory J. (2019) Glycaemic benefit of iGlarLixi in insulin‐naive type 2 diabetes patients with high HbA1c or those with inadequate glycaemic control on two oral antihyperglycaemic drugs in the LixiLan‐O randomized trial. Diabetes, Obesity and Metabolism, 21 (8). pp. 1967-1972. doi:10.1111/dom.13791

Dewulf, Melissa, Köster, Darius, Sinha, Bidisha, Viaris de Lesegno, Christine, Chambon, Valérie, Bigot, Anne, Bensalah, Mona, Negroni, Elisa, Tardif, Nicolas, Podkalicka, Joanna, Johannes, Ludger, Nassoy, Pierre, Butler-Browne, Gillian, Lamaze, Christophe and Blouin, Cedric M. (2019) Dystrophy-associated caveolin-3 mutations reveal that caveolae couple IL6/STAT3 signaling with mechanosensing in human muscle cells. Nature Communications, 10 (1). 1974 . doi:10.1038/s41467-019-09405-5

Dimitriadis, Georgios K., Adya, Raghu, Tan, Bee K., Jones, Terence A., Menon, Vinod S., Ramanjaneya, Manjunath, Kaltsas, Gregory, Miras, Alexander D. and Randeva, Harpal S. (2019) Effects of visfatin on brown adipose tissue energy regulation using T37i cells. Cytokine, 113 . pp. 248-255. doi:10.1016/j.cyto.2018.07.013

Dimitriadis, Georgios K., Nasiri-Ansari, Narjes, Agrogiannis, Georgios, Kostakis, Ioannis D., Randeva, Manpal S., Nikiteas, Nikolaos, Patel, Vanlata H., Kaltsas, Gregory, Papavassiliou, Athanasios G., Randeva, Harpal S. and Kassi, Eva (2019) Empagliflozin improves primary haemodynamic parameters and attenuates the development of atherosclerosis in high fat diet fed APOE knockout mice. Molecular and Cellular Endocrinology, 494 . 110487. doi:10.1016/j.mce.2019.110487

Ditlev, Jonathon A., Vega, Anthony R., Köster, Darius Vasco, Su, Xiaolei, Tani, Tomomi, Lakoduk, Ashley M., Vale, Ronald D., Mayor, Satyajit, Jaqaman, Khuloud and Rosen, Michael K. (2019) A composition-dependent molecular clutch between T cell signaling condensates and actin. eLife, 8 . e42695 . doi:10.7554/eLife.42695

Dong, Xuefei, Yu, Shiran, Wang, Ying, Yang, Min, Xiong, Jie, Hei, Naihao, Dong, Bo, Su, Qing and Chen, Jing (2019) (Pro)renin receptor-mediated myocardial injury, apoptosis, and inflammatory response in rats with diabetic cardiomyopathy. Journal of Biological Chemistry, 294 . pp. 8218-8226. jbc.RA119.007648. doi:10.1074/jbc.RA119.007648

Forster, Rachel, Sarginson, Alexandra, Velichkova, Atanaska, Hogg, Chloe, Dorning, Ashley, Horne, Andrew W., Saunders, Philippa and Greaves, Erin (2019) Macrophage-derived insulin-like growth factor-1 is a key neurotrophic and nerve-sensitizing factor in pain associated with endometriosis. The FASEB Journal, 33 (10). pp. 11210-11222. doi:10.1096/fj.201900797R

Gill, Manjot, Motta-Mejia, Carolina, Kandzija, Neva, Cooke , William, Zhang, Wei, Cerdeira, Ana Sofia, Bastie, Claire C., Redman, Christopher W. and Vatish, Manu (2019) Placental syncytiotrophoblast-derived extracellular vesicles carry active NEP (Neprilysin) and are increased in preeclampsia. Hypertension, 73 (5). pp. 1112-1119. doi:10.1161/HYPERTENSIONAHA.119.12707

Hanson, Petra and Barber, Thomas M. (2019) Should we use BMI as a selection criterion for bariatric surgery? Expert Reviews in Endocrinology and Metabolism, 14 (4). pp. 221-223. doi:10.1080/17446651.2019.1618184

Horne, Andrew W., Ahmad, S. Furquan, Carter, Roderick, Simitsidellis, Ioannis, Greaves, Erin, Hogg, Chloe, Morton, Nicholas M. and Saunders, Philippa T. K. (2019) Repurposing dichloroacetate for the treatment of women with endometriosis. Proceedings of the National Academy of Sciences of the United States of America, 116 (51). pp. 25389-25391. doi:10.1073/pnas.1916144116

Kandzija, Neva, Zhang, Wei, Motta-Mejia, Carolina, Mhlomi, Vuyane, McGowan-Downey, Jennifer, James, Tim, Cerdeira, Ana Sofia, Tannetta, Dionne, Sargent, Ian, Redman, Christopher W., Bastie, Claire C. and Vatish, Manu (2019) Placental extracellular vesicles express active dipeptidyl peptidase IV ; levels are increased in gestational diabetes mellitus. Journal of Extracellular Vesicles, 8 (1). 1617000. doi:10.1080/20013078.2019.1617000

Komarzynski, Sandra, Bolborea, Matei, Huang, Qi, Finkenstädt, Bärbel and Lévi, Francis A. (2019) Predictability of individual circadian phase during daily routine for medical applications of circadian clocks. JCI Insight, 4 (18). e130423. doi:10.1172/jci.insight.130423

Kong, Tingting, Qiu, Kaixin, Liu, Minghui, Cheng, Baohua, Pan, Yanyou, Yang, Chunqing, Chen, Jing and Wang, Chunmei (2019) Orexin-A protects against oxygen-glucose deprivation/reoxygenation-induced cell damage by inhibiting endoplasmic reticulum stress-mediated apoptosis via the Gi and PI3K signaling pathways. Cellular Signalling, 62 . 109348. doi:10.1016/j.cellsig.2019.109348

Küey, Cansu, Larocque, Gabrielle, Clarke, Nicholas I. and Royle, Stephen J. (2019) Unintended perturbation of protein function using GFP nanobodies in human cells. Journal of Cell Science, 132 (21). jcs234955. doi:10.1242/jcs.234955

Mozdiak, Ella, Wicaksono, Alfian, Covington, James A. and Arasaradnam, Ramesh P. (2019) Colorectal cancer and adenoma screening using urinary volatile organic compound (VOC) detection : early results from a single-centre bowel screening population (UK BCSP). Techniques in Coloproctology, 23 (4). pp. 343-351. doi:10.1007/s10151-019-01963-6

Okyar, Alper, Kumar, Swati, Filipski, Elisabeth, Piccolo, Enza, Ozturk, Narin, Xandri-Monje, Helena, Pala-Kara, Zeliha, Abraham, Kristin, Gato de Jesus Gomes, Ana Rita, Orman, Mehmet N., Li, Robert Xiao-Mei, Dallmann, Robert, Lévi, Francis A. and Ballesta, Annabelle (2019) Sex-, feeding-, and circadian time-dependency of P-glycoprotein expression and activity - implications for mechanistic pharmacokinetics modeling. Scientific Reports, 9 . 10505. doi:10.1038/s41598-019-46977-0

Olin-Sandoval, Viridiana, Yu, Jason Shu Lim, Miller-Fleming, Leonor, Alam, Mohammad T., Kamrad, Stephan, Correia-Melo, Clara, Haas, Robert, Segal, Joanna, Peña Navarro, David Alejandro, Herrera-Dominguez, Lucia, Méndez-Lucio, Oscar, Vowinckel, Jakob, Mülleder, Michael and Ralser, Markus (2019) Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism. Nature, 572 (7768). pp. 249-253. doi:10.1038/s41586-019-1442-6

Rabbani, Naila and Thornalley, Paul J. (2019) Glyoxalase 1 modulation in obesity and diabetes. Antioxidants & Redox Signaling, 30 (3). pp. 354-374. doi:10.1089/ars.2017.7424

Ramazzotti, Matteo, Stefanini, Irene, Di Paola, Monica, De Filippo, Carlotta, Rizzetto, Lisa, Berná, Luisa, Dapporto, Leonardo, Rivero, Damariz, Tocci, Noemi, Weil, Tobias, Lenucci, Marcello S., Lionetti, Paolo and Cavalieri, Duccio (2019) Population genomics reveals evolution and variation of Saccharomyces cerevisiae in the human and insects gut. Environmental Microbiology, 21 (1). pp. 50-71. doi:10.1111/1462-2920.14422

Richardson, Sarah, Rawlings, Thomas M., Muter, Joanne, Walker, Marc, Brosens, Jan J., Cameron, Neil R. and Eissa, Ahmed M. (2019) Covalent attachment of fibronectin onto emulsion‐templated porous polymer scaffolds enhances human endometrial stromal cell adhesion, infiltration, and function. Macromolecular Bioscience, 19 (2). 1800351. doi:10.1002/mabi.201800351

Robb, Nicole C., Taylor, Jonathan M., Kent, Amy, Pambos, Oliver J., Gilboa, Barak, Evangelidou, Maria, Mentis, Alexios-Fotios A. and Kapanidis, Achillefs N. (2019) Rapid functionalisation and detection of viruses via a novel Ca2+-mediated virus-DNA interaction. Scientific Reports, 9 (1). 16219. doi:10.1038/s41598-019-52759-5

Rohn, Jennifer L., Mostowy, Serge, King, Jason S., Unnikrishnan, Meera and Gutierrez, Maximiliano G. (2019) The UK cellular microbiology network : exploring the host‐bacterial interface. Cellular Microbiology, 21 (9). e13081. doi:10.1111/cmi.13081

Shah, Poonam, Chaumet, Alexandre, Royle, Stephen J. and Bard, Frederic A. (2019) The NAE Pathway : autobahn to the nucleus for cell surface receptors. Cells, 8 (8). 915. doi:10.3390/cells8080915

Shibusawa, Ryo, Yamada, Eijiro, Okada, Shuichi, Nakajima, Yasuyo, Bastie, Claire C., Maeshima, A., Kaira, K. and Yamada, Masanobu (2019) Dapagliflozin rescues endoplasmic reticulum stress-mediated cell death. Scientific Reports, 9 (1). 9887 . doi:10.1038/s41598-019-46402-6

Slater, Ross T., Frost, Lucy R., Jossi, Sian E, Millard, Andrew D. and Unnikrishnan, Meera (2019) Clostridioides difficile LuxS mediates inter-bacterial interactions within biofilms. Scientific Reports, 9 (1). 9903. doi:10.1038/s41598-019-46143-6

Valoskova, Katarina, Biebl, Julia, Roblek, Marko, Emtenani, Shamsi, Gyoergy, Attila, Misova, Michaela, Ratheesh, Aparna, Reis-Rodrigues, Patricia, Shkarina, Kateryna, Larsen, Ida Signe Bohse, Vakhrushev, Sergey Y., Clausen, Henrik and Siekhaus, Daria E. (2019) A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion. eLife, 8 . e41801. doi:10.7554/eLife.41801.001

Wang, Qin-Qin, Wang, Chun-Mei, Cheng, Bao-Hua, Yang, Chun-Qing, Bai, Bo and Chen, Jing (2019) Signaling transduction regulated by 5-hydroxytryptamine 1A receptor and orexin receptor 2 heterodimers. Cellular Signalling, 54 . pp. 46-58. doi:10.1016/j.cellsig.2018.11.014

Wang, Qinqin, Wang, Chunmei, Ji, Bingyuan, Zhou, Jiawei, Yang, Chunqing and Chen, Jing (2019) Hapln2 in neurological diseases and its potential as therapeutic target. Frontiers in Aging Neuroscience, 11 . 60. doi:10.3389/fnagi.2019.00060

Winczura, Alicja, Appanah, Rowin, Tatham, Michael H., Hay, Ronald T. Hay and De Piccoli, Gaicomo (2019) The S phase checkpoint promotes the Smc5/6 complex dependent SUMOylation of Pol2, the catalytic subunit of DNA polymerase ε. PLoS Genetics, 15 (11). e1008427. doi:10.1371/journal.pgen.1008427

Agama Study Group (Including: Zhou, Zhemin, Alikhan, Nabil-Fareed, Mohamed, Khaled, Fan, Yulei, Achtman, Mark and Tyne, William). (2019) The EnteroBase user's guide, with case studies on Salmonella transmissions, Yersinia pestis phylogeny and Escherichia core genomic diversity. Genome Research . 251678.119. doi:10.1101/gr.251678.119

von Loeffelholz, Ottilie, Peña, Alejandro, Drummond, Douglas R., Cross, R. A. and Moores, Carolyn Ann (2019) Cryo-EM structure (4.5-Å) of yeast Kinesin-5–microtubule complex reveals a distinct binding footprint and mechanism of drug resistance. Journal of Molecular Biology, 431 (4). pp. 864-872. doi:10.1016/j.jmb.2019.01.011