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Number of items: 38.
Journal Article
Clement, Mathew, Pearson, James A., Gras, Stephanie, Berg, Hugo van den, Lissina, Anya, Llewellyn-Lacey, Sian, Willis, Mark D., Dockree, Tamsin, McLaren, James E., Keruche-Makinde, Julia E., Gostick, Emma, Robertson, Neil P., Rossjohn, Jamie, Burrows, Scott R., Price, David A., Wong, F. Susan, Peakman, Mark, Skowera, Ania and Wooldridge, Linda (2016) Targeted suppression of autoreactive CD8+ T-cell activation using blocking anti-CD8 antibodies. Scientific Reports, 6 . 35332 . doi:10.1038/srep35332 ISSN 2045-2322.
Zhang, Fang, Masania, Jinit , Anwar, Attia, Xue, Mingzhan, Zehnder, Daniel, Kanji, Hemali, Rabbani, Naila and Thornalley, Paul J. (2016) The uremic toxin oxythiamine causes functional thiamine deficiency in end-stage renal disease by inhibiting transketolase activity. Kidney International, 90 (2). pp. 396-403. doi:10.1016/j.kint.2016.03.010 ISSN 0085-2538.
Siamantouras, Eleftherios, Hills, Claire E., Squires, Paul E. and Liu, Kuo-Kang (2016) Quantifying cellular mechanics and adhesion in renal tubular injury using single cell force spectroscopy. Nanomedicine : Nanotechnology, Biology, and Medicine, 12 (4). pp. 1013-1021. doi:10.1016/j.nano.2015.12.362 ISSN 1549-9634.
Sudlow, Cathie, Gallacher, John, Allen, Naomi E., Beral, V. (Valerie), Burton, Paul R., Danesh, John, Downey, Paul, Elliott, Paul, Green, Jane, Landray, Martin J., Liu, Bette, Matthews, Paul, Ong, Giok J., Pell, Jill, Silman, Alan J., Young, Alan, Sprosen, Tim, Peakman, Tim and Collins, Rory (2015) UK Biobank : an Open Access resource for identifying the causes of a wide range of complex diseases of middle and old age. PLoS Medicine, Volume 12 (Number 3). pp. 1-10. Article number e1001779. doi:10.1371/journal.pmed.1001779 ISSN 1549-1277.
Antonysunil, Adaikalakoteswari, Jayashri, Ramamurthy, Sukumar, Nithya, Venkataraman, Hema, Pradeepa, Rajendra, Gokulakrishnan, Kuppan, Anjana, Ranjit, McTernan, P. G., Tripathi, Gyanendra, Patel, Vinod, Kumar, Sudhesh, Mohan, Viswanathan and Saravanan, Ponnusamy (2014) Vitamin B12 deficiency is associated with adverse lipid profile in Europeans and Indians with type 2 diabetes. Cardiovascular Diabetology, Volume 13 (Number 1). pp. 1-7. Article number 129. doi:10.1186/s12933-014-0129-4 ISSN 1475-2840.
Oyebode, Oyinlola, Gordon-Dseagu, V., Walker, A. and Mindell, J. S. (2014) Fruit and vegetable consumption and all-cause, cancer and CVD mortality : analysis of Health Survey for England data. Journal of Epidemiology & Community Health, 68 (9). pp. 856-862. doi:10.1136/jech-2013-203500 ISSN 0143-005X.
Siamantouras, Eleftherios, Hills, Claire E., Younis, Mustafa Y. G., Squires, Paul E. and Liu, Kuo-Kang (2014) Quantitative investigation of calcimimetic R568 on beta cell adhesion and mechanics using AFM single-cell force spectroscopy. FEBS Letters, Volume 588 (Number 7). pp. 1173-1178. doi:10.1016/j.febslet.2014.02.058 ISSN 0014-5793.
Hills, Claire E., Jin, Tianrong, Siamantouras, Eleftherios, Liu, Kuo-Kang, Jefferson, Kieran P. and Squires, Paul E. (2013) 'Special K' and a loss of cell-to-cell adhesion in proximal tubule-derived epithelial cells : modulation of the adherens junction complex by ketamine. PLoS One, Volume 8 (Number 8). Article number e71819. doi:10.1371/journal.pone.0071819 ISSN 1932-6203.
Hills, Claire E., Kerr, Michael I., Wall, Mark J. and Squires, Paul E. (2013) Visfatin reduces gap junction mediated cell-to-cell communication in proximal tubule-derived epithelial cells. Cellular Physiology & Biochemistry, Volume 32 (Number 5). pp. 1200-1212. doi:10.1159/000354519 ISSN 1015-8987.
Virtue, Sam, Feldmann, Helena, Christian, Mark, Tan, Chong Yew, Masoodi, Mojgan, Dale, Martin, Lelliott, Chris, Burling, Keith, Campbell, Mark, Eguchi, Naomi, Voshol, Peter, Sethi, Jaswinder K., Parker, Malcolm G., Urade, Yoshihiro, Griffin, Julian L., Cannon, Barbara and Vidal-Puig, Antonio (2012) A new role for lipocalin prostaglandin d synthase in the regulation of brown adipose tissue substrate utilization. Diabetes, 61 (12). pp. 3139-3147. doi:10.2337/db12-0015 ISSN 0012-1797.
Kelly, M. Ann , Rees, Simon D., Hydrie, M. Zafar I., Shera, A. Samad, Bellary, Srikanth, O'Hare, J. Paul, Kumar, Sudhesh, Taheri, S., Basit, Abdul and Barnett, Anthony H. (2012) Circadian gene variants and susceptibility to type 2 diabetes : a pilot study. PLoS ONE, Vol.7 (No.4). e32670. doi:10.1371/journal.pone.0032670 ISSN 1932-6203.
Hills, Claire E., Siamantouras, Eleftherios, Smith, S. W., Cockwell, Paul, Liu, Kuo-Kang and Squires, Paul E. (2012) TGFβ modulates cell-cell communication in early epithelial-to-mesenchymal transition. Diabetologia, Vol.55 (No.3). pp. 812-824. doi:10.1007/s00125-011-2409-9 ISSN 0012-186X.
Al-Qahtani, S., Heath, Andrew C., Quenby, Siobhan, Dawood, F., Floyd, R., Burdyga, T. and Wray, S. (2012) Diabetes is associated with impairment of uterine contractility and high Caesarean section rate. Diabetologia, Vol.55 (No.2). pp. 489-498. doi:10.1007/s00125-011-2371-6 ISSN 0012-186X.
Hills, Claire E., Younis, Mustafa Y. G., Bennett, Jeanette, Siamantouras, Eleftherios, Liu, Kuo-Kang and Squires, Paul E. (2012) Calcium-sensing receptor activation increases cell-cell adhesion and ß-cell function. Cellular Physiology and Biochemistry, Vol.30 (No.3). pp. 575-586. doi:10.1159/000341439 ISSN 1015-8987.
Larkin, James Robert, Zhang, F. (Fang), Godfrey, L. (Lisa), Molostvov, Guerman, Zehnder, Daniel, Rabbani, Naila and Thornalley, Paul J. (2012) Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes. PLoS One, Vol.7 (No.12). Article no. e53175. doi:10.1371/journal.pone.0053175 ISSN 1932-6203.
Rees, Simon D., Hydrie, M. Zafar I., O'Hare, J. Paul, Kumar, Sudhesh, Shera, A. Samad, Basit, Abdul, Barnett, A. H. and Kelly, M. Ann (2011) Effects of 16 genetic variants on fasting glucose and type 2 diabetes in South Asians : ADCY5 and GLIS3 variants may predispose to type 2 diabetes. PLoS ONE, Vol.6 (No.9). doi:10.1371/journal.pone.0024710 ISSN 1932-6203.
Rabbani, Naila and Thornalley, Paul J. (2011) Emerging role of thiamine therapy for prevention and treatment of early-stage diabetic nephropathy. Diabetes, Obesity and Metabolism, Volume 13 (Number 7). pp. 577-583. doi:10.1111/j.1463-1326.2011.01384.x ISSN 1462-8902.
Rees, Simon D., Hydrie, M. Z. I., Shera, A. S., Kumar, Sudhesh, O'Hare, J. Paul, Barnett, A. H., Basit, A. and Kelly, M. Ann (2011) Replication of 13 genome-wide association (GWA)-validated risk variants for type 2 diabetes in Pakistani populations. Diabetologia, Volume 54 (Number 6). pp. 1368-1374. doi:10.1007/s00125-011-2063-2 ISSN 0012-186X.
Rabbani, Naila and Thornalley, Paul J. (2011) Glyoxalase in diabetes, obesity and related disorders. Seminars in Cell and Developmental Biology, Vol.22 (No.3). pp. 309-317. doi:10.1016/j.semcdb.2011.02.015 ISSN 1084-9521.
Rees, Simon D., Islam, M., Hydrie, M. Z. I., Chaudhary, B., Bellary, Srikanth, Hashmi, Shiraz, O'Hare, J. Paul, Kumar, Sudhesh, Sanghera, D. K., Chaturvedi, N., Barnett, A. H., Shera, A. S., Weedon, Michael N., Basit, A., Frayling, Timothy M., Kelly, M. Ann and Jafar, T. H. (2011) An FTO variant is associated with Type 2 diabetes in South Asian populations after accounting for body mass index and waist circumference. Diabetic Medicine, Volume 28 (Number 6). pp. 673-680. doi:10.1111/j.1464-5491.2011.03257.x ISSN 0742-3071.
Hills, Claire E. and Squires, Paul E. (2011) The role of TGF-β and epithelial-to mesenchymal transition in diabetic nephropathy. Cytokine & Growth Factor Reviews . doi:10.1016/j.cytogfr.2011.06.002 ISSN 1359-6101.
MAGIC (Including:
). (2010) Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nature Genetics, Vol.42 (No.11). pp. 937-948. doi:10.1038/ng.686 ISSN 1061-4036.Sturt, Jackie, Hearnshaw, Hilary and Wakelin, M. (2010) Validity and reliability of the DMSES UK : a measure of self-efficacy for type 2 diabetes self-management. Primary Health Care Research and Development, Vol.11 (No.4). pp. 374-381. doi:10.1017/S1463423610000101 ISSN 1463-4236.
Jenei, Zsuzsanna A., Borthwick, Karen, Zammit, Victor A. and Dixon, Ann M. (2009) Self-association of transmembrane domain 2 (TM2), but Not TM1, incCarnitine palmitoyltransferase 1A role of GXXXG(A) motifs. Journal of Biological Chemistry, Vol.284 (No.11). pp. 6988-6997. doi:10.1074/jbc.M808487200 ISSN 0021-9258.
Hills, Claire E., Bland, Rosemary, Bennett, Jeanette, Ronco, Pierre M. and Squires, Paul E. (2009) TGF-beta 1 mediates glucose-evoked up-regulation of connexin-43 cell-to-cell communication in HCD-cells. Cellular Physiology and Biochemistry, Vol.24 (No.3-4). pp. 177-186. doi:10.1159/000233244 ISSN 1015-8987.
Kitsou-Mylona, Isidora, Burns, Christopher J., Squires, Paul E., Persaud, Shanta J. and Jones, Peter M. (2008) A role for the extracellular calcium-sensing receptor in cell-cell communication in pancreatic islets of Langerhans. Cellular Physiology and Biochemistry, Vol.22 (No.5-6). pp. 557-566. doi:10.1159/000185540 ISSN 1015-8987.
Sturt, Jackie, Whitlock, Sandra, Fox, Claudine, Hearnshaw, Hilary, Farmer, A. J., Wakelin, M., Eldridge, Sandra, Griffiths, Frances and Dale, Jeremy (2008) Effects of the diabetes manual 1:1 structured education in primary care. Diabetic Medicine, Vol.25 (No.6). pp. 722-731. doi:10.1111/j.1464-5491.2008.02451.x ISSN 0742-3071.
Zammit, Victor A. (2008) Carnitine palmitoyltransferase 1: Central to cell function. IUBMB Life, Vol.60 (No.5). pp. 347-354. doi:10.1002/iub.78 ISSN 1521-6543.
Lloyd, Cathy E., Sturt, Jackie, Johnson, M., Mughal, Shanaz, Collins, Gary S. and Barnett, A. H. (2008) Development of alternative methods of data collection in South Asians with Type 2 diabetes. Diabetic Medicine, Volume 25 (Number 4). pp. 455-462. doi:10.1111/j.1464-5491.2008.02401.x ISSN 0742-3071.
Ramraeheya, Reshma D., Muller, Danu S., Squires, Paul E., Brereten, Helen, Sugden, David (Researcher in life sciences), Huang, Guo Cai, Amiel, Stephanie, Jones, Peter M. and Persaud, Shanta J. (2008) Function and expression of melatonin receptors on human pancreatic islets. Journal of Pineal Research , Volume 44 (Number 3). pp. 273-279. doi:10.1111/j.1600-079X.2007.00523.x ISSN 0742-3098.
Hills, Claire E., Squires, Paul E. and Bland, Rosemary (2008) SGK and disturbed renal sodium transport in diabetes. Journal of Endocrinology, Vol.199 (No.3). pp. 343-349. doi:10.1677/JOE-08-0295 ISSN 0022-0795.
Hearnshaw, H., Wright, K., Dale, Jeremy, Sturt, Jackie, Vermeire, E. and van Royen, P. (2007) Development and validation of the Diabetes Obstacles Questionnaire (DOQ) to assess obstacles in living with Type 2 diabetes. Diabetic Medicine, Vol.24 (No.8). pp. 878-882. doi:10.1111/j.1464-5491.2007.02137.x ISSN 0742-3071.
Sturt, Jackie, Taylor, Hafrun, Docherty, Andrea, Dale, Jeremy and Taylor, Louise (2006) A psychological approach to providing self-management education for people with type 2 diabetes : the diabetes manual. Biomed Central Fanily Practice, Vol.7 (No.70). doi:10.1186/1471-2296-7-70 ISSN 1471-2296.
Book Item
Squires, Paul E., Jones, Peter J., Younis, Mustafa Y. G. and Hills, Claire E. (2014) The calcium-sensing receptor and beta-cell function. In: Litwack, Gerald, (ed.) The Pancreatic beta-cell. Vitamins & Hormones, Volume 95 . UK: Academic Press , pp. 249-267. ISBN 9780128001745
Conference Item
Kos, Katarina, Wong, Steve, Tan, Bee K., Gummesson, Anders, Jernas, Margareta, Franck, Niclas, Kerrigan, David, Nystrom, Fredrik H., Carlsson, Lena M. S., Randeva, Harpal S., Pinkney, Jonathan H. and Wilding, John P. H. (2009) Regulation of the fibrosis and angiogenesis promoter SPARC/osteonectin in human adipose tissue by weight change, leptin, insulin, and glucose. In: 69th Annual Meeting of the American Diabetes Association, New Orleans, LA, June 05-09, 2009. Published in: Diabetes, Vol.58 (No.8). pp. 1780-1788. doi:10.2337/db09-0211 ISSN 0012-1797.
Rabbani, Naila and Thornalley, Paul J. (2008) Dicarbonyls linked to damage in the powerhouse : glycation of mitochondrial proteins and oxidative stress. In: 3rd Intracellular Proteolysis Meeting, Canary Isl, Spain, Mar 05-07, 2008. Published in: Biochemical Society Transactions, Vol.36 (Pt.5). pp. 1045-1050. doi:10.1042/BST0361045 ISSN 0300-5127.
Rabbani, Naila and Thornalley, Paul J. (2008) The dicarbonyl proteome - proteins susceptible to dicarbonyl glycation at functional sites in health, aging, and disease. In: 9th International Symposium on the Maillard Reaction, Munich, Germany, Sep, 2007. Published in: Annals of the New York Academy of Sciences, Volume 1126 pp. 124-127. ISBN 978-1-57331-719-1. doi:10.1196/annals.1433.043 ISSN 0077-8923.
Journal Item
Hills, Claire E., Squires, Paul E. and Bland, Rosemary (2008) Serum and glucocorticoid regulated kinase and disturbed renal sodium transport in diabetes. Journal of Endocrinology, Vol.199 (No.3). pp. 343-349. ISSN 0022-0795 doi:10.1677/JOE-08-0295