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Release your inhibitions : the role of post‐inhibitory rebound and synaptic inhibition in the generation of expiratory activity
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Huckstepp, Robert T. R. and Funk, Gregory D. (2021) Release your inhibitions : the role of post‐inhibitory rebound and synaptic inhibition in the generation of expiratory activity. Journal of Physiology, 599 (24). pp. 5331-5332. doi:10.1113/JP282482 ISSN 0022-3751.
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Official URL: https://doi.org/10.1113/JP282482
Abstract
Breathing in mammals is a fundamental behaviour produced by movements generated and controlled by the central nervous system. The formation of the diaphragm in mammals has led to a unique phenomenon, inspiratory led breathing. In fact, in most mammals at rest, only inspiration is active – expiration is passive. As such research into mechanisms of respiratory rhythm generation has focussed on the inspiratory oscillator, the preBötzinger Complex (preBötC). Whilst we now understand a large number of fundamental properties underlying the behaviour of the preBötC, much less is known about its expiratory counterpart that generates active expiration under conditions of increased respiratory drive; e.g., exercise.
| Item Type: | Journal Article | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Subjects: | Q Science > QP Physiology | ||||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) | ||||||||
| Library of Congress Subject Headings (LCSH): | Respiration -- Regulation, Neurophysiology | ||||||||
| Journal or Publication Title: | Journal of Physiology | ||||||||
| Publisher: | Wiley-Blackwell Publishing Ltd. | ||||||||
| ISSN: | 0022-3751 | ||||||||
| Official Date: | 15 December 2021 | ||||||||
| Dates: |
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| Volume: | 599 | ||||||||
| Number: | 24 | ||||||||
| Page Range: | pp. 5331-5332 | ||||||||
| DOI: | 10.1113/JP282482 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Reuse Statement (publisher, data, author rights): | "This is the peer reviewed version of the following article:Huckstepp, R.T.R. and Funk, G.D. (2021), Release your inhibitions: The role of post-inhibitory rebound and synaptic inhibition in the generation of expiratory activity. J Physiol, 599: 5331-5332, which has been published in final form at http://dx.doi.org/10.1113/JP282482. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited." | ||||||||
| Access rights to Published version: | Restricted or Subscription Access | ||||||||
| Copyright Holders: | © 2021 The Authors. The Journal of Physiology © 2021 The Physiological Society | ||||||||
| Date of first compliant deposit: | 21 December 2021 | ||||||||
| Date of first compliant Open Access: | 15 November 2022 |
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