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Release your inhibitions : the role of post‐inhibitory rebound and synaptic inhibition in the generation of expiratory activity

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Huckstepp, Robert T. R. and Funk, Gregory D. (2021) Release your inhibitions : the role of post‐inhibitory rebound and synaptic inhibition in the generation of expiratory activity. Journal of Physiology, 599 (24). pp. 5331-5332. doi:10.1113/JP282482 ISSN 0022-3751.

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Official URL: https://doi.org/10.1113/JP282482

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Abstract

Breathing in mammals is a fundamental behaviour produced by movements generated and controlled by the central nervous system. The formation of the diaphragm in mammals has led to a unique phenomenon, inspiratory led breathing. In fact, in most mammals at rest, only inspiration is active – expiration is passive. As such research into mechanisms of respiratory rhythm generation has focussed on the inspiratory oscillator, the preBötzinger Complex (preBötC). Whilst we now understand a large number of fundamental properties underlying the behaviour of the preBötC, much less is known about its expiratory counterpart that generates active expiration under conditions of increased respiratory drive; e.g., exercise.

Item Type: Journal Article
Subjects: Q Science > QP Physiology
Divisions: Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- )
Library of Congress Subject Headings (LCSH): Respiration -- Regulation, Neurophysiology
Journal or Publication Title: Journal of Physiology
Publisher: Wiley-Blackwell Publishing Ltd.
ISSN: 0022-3751
Official Date: 15 December 2021
Dates:
DateEvent
15 December 2021Published
15 November 2021Available
10 November 2021Accepted
Volume: 599
Number: 24
Page Range: pp. 5331-5332
DOI: 10.1113/JP282482
Status: Peer Reviewed
Publication Status: Published
Reuse Statement (publisher, data, author rights): "This is the peer reviewed version of the following article:Huckstepp, R.T.R. and Funk, G.D. (2021), Release your inhibitions: The role of post-inhibitory rebound and synaptic inhibition in the generation of expiratory activity. J Physiol, 599: 5331-5332, which has been published in final form at http://dx.doi.org/10.1113/JP282482. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited."
Access rights to Published version: Restricted or Subscription Access
Copyright Holders: © 2021 The Authors. The Journal of Physiology © 2021 The Physiological Society
Date of first compliant deposit: 21 December 2021
Date of first compliant Open Access: 15 November 2022

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