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Fluorescently labeled protein-polymer bioconjugates using protein-derived macroinitiators from living radical polymerization
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Nicolas, Julien, Miguel, V., Manovani, G. and Haddleton, David M. (2008) Fluorescently labeled protein-polymer bioconjugates using protein-derived macroinitiators from living radical polymerization. In: International Symposium on Polymers for Biomedical Applications/232nd National Meeting of the American-Chemical-Society (ACS), San Francisco, CA, 10-14 Sep 2006 . Published in: Polymers for Biomedical Applications, Volume 977 pp. 78-94. doi:10.1021/bk-2008-0977.ch006 ISSN 0097-6156.
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Abstract
Bovine Serum Albumin (BSA) and lysozyme have been chemically transformed into macroinitiators for the synthesis of fluorescent bioconjugates by living radical polymerization. A new fluorescent monomer based on rhodamine B has been synthesized and incorporated into the polymer backbone of the bioconjugate by copolymerization. This provides a new strategy for the synthesis of fluorescent bioconjugates with improved traceability in biological environments, during biomedical assays
Item Type: | Conference Item (Paper) | ||||
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Subjects: | Q Science > QD Chemistry Q Science > QP Physiology |
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Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
Library of Congress Subject Headings (LCSH): | Polymerization, Bioconjugates | ||||
Journal or Publication Title: | Polymers for Biomedical Applications | ||||
Publisher: | American Chemical Society | ||||
ISSN: | 0097-6156 | ||||
Official Date: | 2008 | ||||
Dates: |
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Volume: | Volume 977 | ||||
Page Range: | pp. 78-94 | ||||
DOI: | 10.1021/bk-2008-0977.ch006 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Conference Paper Type: | Paper | ||||
Title of Event: | International Symposium on Polymers for Biomedical Applications/232nd National Meeting of the American-Chemical-Society (ACS) | ||||
Type of Event: | Conference | ||||
Location of Event: | San Francisco, CA | ||||
Date(s) of Event: | 10-14 Sep 2006 |
Data sourced from Thomson Reuters' Web of Knowledge
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