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Soft polymer-based technique for cellular force sensing
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Yu, Zhuonan and Liu, Kuo-Kang (2021) Soft polymer-based technique for cellular force sensing. Polymers, 13 (16). 2672. doi:10.3390/polym13162672 ISSN 2073-4360.
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WRAP-Soft-polymer-based-technique-cellular-force-sensing-2021.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (2407Kb) | Preview |
Official URL: http://dx.doi.org/10.3390/polym13162672
Abstract
Soft polymers have emerged as a vital type of material adopted in biomedical engineering to perform various biomechanical characterisations such as sensing cellular forces. Distinct advantages of these materials used in cellular force sensing include maintaining normal functions of cells, resembling in vivo mechanical characteristics, and adapting to the customised functionality demanded in individual applications. A wide range of techniques has been developed with various designs and fabrication processes for the desired soft polymeric structures, as well as measurement methodologies in sensing cellular forces. This review highlights the merits and demerits of these soft polymer-based techniques for measuring cellular contraction force with emphasis on their quantitativeness and cell-friendliness. Moreover, how the viscoelastic properties of soft polymers influence the force measurement is addressed. More importantly, the future trends and advancements of soft polymer-based techniques, such as new designs and fabrication processes for cellular force sensing, are also addressed in this review. View Full-Text
Item Type: | Journal Article | ||||||
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Subjects: | T Technology > TA Engineering (General). Civil engineering (General) | ||||||
Divisions: | Faculty of Science, Engineering and Medicine > Engineering > Engineering | ||||||
Library of Congress Subject Headings (LCSH): | Polymers, Cellular recognition, Biomechanics, Cells -- Mechanical properties, Colloids | ||||||
Journal or Publication Title: | Polymers | ||||||
Publisher: | M D P I AG | ||||||
ISSN: | 2073-4360 | ||||||
Official Date: | 10 August 2021 | ||||||
Dates: |
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Volume: | 13 | ||||||
Number: | 16 | ||||||
Article Number: | 2672 | ||||||
DOI: | 10.3390/polym13162672 | ||||||
Status: | Peer Reviewed | ||||||
Publication Status: | Published | ||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||
Date of first compliant deposit: | 12 August 2021 | ||||||
Date of first compliant Open Access: | 12 August 2021 |
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