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Item response theory may account for unequal item weighting and individual-level measurement error in trials that use PROMs : a psychometric sensitivity analysis of the TOPKAT trial
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Harrison, Conrad J., Plessen, Constantin Yves, Liegl, Gregor, Rodrigues, Jeremy N., Sabah, Shiraz A., Cook, Jonathan A., Beard, David J. and Fischer, Felix (2023) Item response theory may account for unequal item weighting and individual-level measurement error in trials that use PROMs : a psychometric sensitivity analysis of the TOPKAT trial. Journal of Clinical Epidemiology, 158 . pp. 62-69. doi:10.1016/j.jclinepi.2023.03.013 ISSN 0895-4356.
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Official URL: https://doi.org/10.1016/j.jclinepi.2023.03.013
Abstract
To apply item response theory as a framework for studying measurement error in superiority trials which use patient-reported outcome measures (PROMs). We reanalyzed data from the TOPKAT trial, which compared the Oxford Knee Score (OKS) responses of patients undergoing partial or total knee replacement, using traditional sum-scoring, after accounting for OKS item characteristics with expected a posteriori (EAP) scoring, and after accounting for individual-level measurement error with plausible value imputation (PVI). We compared the marginalized mean scores of each group at baseline, 2 months, and yearly for 5 years. We used registry data to estimate the minimal important difference (MID) of OKS scores with sum-scoring and EAP scoring. With sum-scoring, we found statistically significant differences in mean OKS score at 2 months (p=0.030) and 1 year (p=0.030). EAP scores produced slightly different results, with statistically significant differences at 1 year (p=0.041) and 3 years (p=0.043). With PVI, there were no statistically significant differences. Psychometric sensitivity analyses can be readily performed for superiority trials using PROMs and may aid the interpretation of results. [Abstract copyright: Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.]
Item Type: | Journal Article | ||||||||||||
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Subjects: | B Philosophy. Psychology. Religion > BF Psychology R Medicine > R Medicine (General) R Medicine > RD Surgery |
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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SWORD Depositor: | Library Publications Router | ||||||||||||
Library of Congress Subject Headings (LCSH): | Item response theory, Psychometrics, Total knee replacement -- Cost effectiveness, Total knee replacement, Outcome assessment (Medical care), Clinical trials | ||||||||||||
Journal or Publication Title: | Journal of Clinical Epidemiology | ||||||||||||
Publisher: | Elsevier Inc. | ||||||||||||
ISSN: | 0895-4356 | ||||||||||||
Official Date: | June 2023 | ||||||||||||
Dates: |
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Volume: | 158 | ||||||||||||
Page Range: | pp. 62-69 | ||||||||||||
DOI: | 10.1016/j.jclinepi.2023.03.013 | ||||||||||||
Status: | Peer Reviewed | ||||||||||||
Publication Status: | Published | ||||||||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||||||||
Date of first compliant deposit: | 25 April 2023 | ||||||||||||
Date of first compliant Open Access: | 25 April 2023 | ||||||||||||
RIOXX Funder/Project Grant: |
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