The Library
Browse by Warwick Author
![]() | Up a level |
Number of items: 59.
Arnison, Paul G., Bibb, Mervyn J., Bierbaum, Gabriele, Bowers, Albert A., Bugni, Tim S., Bulaj, Grzegorz, Camarero, Julio A., Campopiano, Dominic J., Challis, Gregory L., Clardy, Jon et al.
.
(2013)
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.
Natural Product Reports, Vol.30
(No.1).
pp. 108-160.
ISSN 0265-0568
Barry, Sarah M., Kers, Johan A, Johnson, Evan G, Song, Lijiang, Aston, Philip R. , Patel, Bhumit, Krasnoff, Stuart B, Crane, Brian R, Gibson, Donna M, Loria, Rosemary and Challis, Gregory L.. (2012) Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis. Nature Chemical Biology, Vol. 8 (No.10). pp. 814-816. ISSN 1552-4450
Gerc, Amy J., Song, Lijiang, Challis, Gregory L., Stanley-Wall, Nicola R. and Coulthurst, Sarah J.. (2012) The insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycin. PLoS One, Vol.7 (No.9). e44673. ISSN 1932-6203
Lewis, J. W., Morley, N. J., Ahmad, Mark, Challis, Gregory L., Wright, R., Bicker, R. and Morritt, D.. (2012) Structural changes in freshwater fish and chironomids exposed to bacterial exotoxins. Ecotoxicology and Environmental Safety, Vol.80 . pp. 37-44. ISSN 0147-6513
Gomez-Escribano, Juan Pablo, Song, Lijiang, Bibb, Mervyn J. and Challis, Gregory L.. (2012) Posttranslational β-methylation and macrolactamidination in the biosynthesis of the bottromycin complex of ribosomal peptide antibiotics. Chemical Science, Vol.3 (No.12). pp. 3522-3525. ISSN 2041-6520
Schmelz, Stefan, Botting, Catherine H., Song, Lijiang, Kadi, Nadia F., Challis, Gregory L. and Naismith, James H.. (2011) Structural basis for acyl acceptor specificity in the achromobactin biosynthetic enzyme AcsD. Journal of Molecular Biology, Vol.412 (No.3). pp. 495-504. ISSN 0022-2836
Papireddy, Kancharla, Smilkstein, Martin, Kelly, Jane XU, Shweta, Dr., Salem, Shaimaa M., Alhamadsheh, Mamoun, Haynes, Stuart W., Challis, Gregory L. and Reynolds, Kevin A.. (2011) Antimalarial activity of natural and synthetic prodiginines. Journal of Medicinal Chemistry, Vol.54 (No.15). pp. 5296-5306. ISSN 0022-2623
Seipke, R. F., Song, Lijiang, Bicz, Joanna, Laskaris, P., Yaxley, Alice M., Challis, Gregory L. and Loria, Rosemary. (2011) The plant pathogen Streptomyces scabies 87-22 has a functional pyochelin biosynthetic pathway that is regulated by TetR- and AfsR-family proteins. Microbiology, Vol.157 (No.9). pp. 2681-2693. ISSN 1350-0872
Whicher, J. R., Florova, G., Sydor, Paulina K., Singh, R., Alhamadsheh, M., Challis, Gregory L., Reynolds, Kevin A. and Smith, Janet Louise. (2011) Structure and function of the RedJ protein, a thioesterase from the prodiginine biosynthetic pathway in streptomyces coelicolor. Journal of Biological Chemistry, Vol.286 (No.25). pp. 22558-22569. ISSN 0021-9258
Mahenthiralingam, Eshwar, Song, Lijiang, Sass, Andrea, White, J. (Judith), Wilmot, Ceri, Marchbank, Angela, Boaisha, Othman, Paine, James, Knight, D. (David) and Challis, Gregory L.. (2011) Enacyloxins are products of an unusual hybrid modular polyketide synthase encoded by a cryptic burkholderia ambifaria genomic island. Chemistry & Biology, Vol.18 (No.5). pp. 665-677. ISSN 1074-5521
Davis, Carol, Carberry, Stephen, Schrettl, Markus, Singh, Ishwar, Stephens, John C., Barry, Sarah M., Kavanagh, Kevin, Challis, Gregory L., Brougham, Dermot and Doyle, S. (Sean). (2011) The role of glutathione S-transferase GliG in gliotoxin biosynthesis in aspergillus fumigatus. Chemistry & Biology, Vol.18 (No.4). pp. 542-552. ISSN 1074-5521
Sydor, Paulina K., Barry, Sarah M., Odulate, Olanipekun M., Barona-Gomez, Francisco, Haynes, Stuart W., Corre, Christophe, Song, Lijiang and Challis, Gregory L.. (2011) Regio- and stereodivergent antibiotic oxidative carbocyclizations catalysed by Rieske oxygenase-like enzymes. Nature Chemistry, Vol.3 (No.5). pp. 388-392. ISSN 1755-4330
Laureti, L., Song, Lijiang, Huang, S., Corre, Christophe, Leblond, Pierre, Challis, Gregory L. and Aigle, B.. (2011) Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens. Proceedings of the National Academy of Sciences of the United States of America, Vol.108 (No.15). pp. 6258-6263. ISSN 0027-8424
Bunet, R., Song, Lijiang, Mendes, M. V., Corre, Christophe, Hotel, L., Rouhier, N., Framboisier, X., Leblond, Pierre, Challis, Gregory L. and Aigle, B.. (2011) Characterization and manipulation of the pathway-specific late regulator AlpW reveals streptomyces ambofaciens as a new producer of kinamycins. Journal of Bacteriology, Vol.193 (No.5). pp. 1142-1153. ISSN 0021-9193
Malet, Nicolas, Song, Lijiang, Corre, Christophe and Challis, Gregory L. (2011) Structure-activity relationship and biosynthesis of signaling molecules controlling methylenomycin antibiotic production in Streptomyces coelicolor. American Chemical Society. Abstracts of Papers (at the National Meeting), Vol.241 (No.142-BIOL ). ISSN 0065-7727
Haynes, Stuart W., Sydor, Paulina K., Corre, Christophe, Song, Lijiang and Challis, Gregory L.. (2011) Stereochemical elucidation of streptorubin B. Journal of the American Chemical Society, Vol.133 (No.6). pp. 1793-1798. ISSN 0002-7863
Haynes, Stuart W., Sydor, Paulina K., Corre, Christophe and Challis, Gregory L. (2011) Elucidation of pathways for antibiotic biosynthesis in streptomyces coelicolor A3(2). In: Wrigley, Stephen, (ed.) Functional Molecules from Natural Sources. Special publication (Royal Society of Chemistry (Great Britain)) (No.320). Cambridge: Royal Society of Chemistry, pp. 149-160. ISBN 9781847552594
Aigle, B., Bunet, R., Corre, Christophe, Garenaux, Amélie, Hotel, L., Huang, S., Laureti, L., Lautru, Sylvie, Mendes, V. M., Nezbedová, S., Nguyen, H., Song, Lijiang, Challis, Gregory L., Leblond, Pierre and Pernodet, Jean-Luc (2011) Genome-guided exploration of streptomyces ambofaciens secondary metabolism. In: Streptomyces : molecular biology and biotechnology. [Wymondham]: Caister Academic, pp. 179-194. ISBN 9781904455776
Oves-Costales , D. and Challis, Gregory L. (2011) Studies on the biosynthesis of the anthrax siderophore petrobactin. In: Wrigley, Stephen, (ed.) Functional Molecules from Natural Sources. Special publication (Royal Society of Chemistry (Great Britain)) (No.320). Cambridge: Royal Society of Chemistry, pp. 184-194. ISBN 9781847552594
Corre, Christophe, Haynes, Stuart W., Malet, Nicolas, Song, Lijiang and Challis, Gregory L.. (2011) A butenolide intermediate in methylenomycin furan biosynthesis is implied by incorporation of stereospecifically C-13-labelled glycerols. Chemical Communications, Vol.46 (No.23). pp. 4079-4081. ISSN 1359-7345
Patel, Prakash, 1983-, Song, Lijiang and Challis, Gregory L.. (2010) Distinct extracytoplasmic siderophore binding proteins recognize ferrioxamines and ferricoelichelin in streptomyces coelicolor A3(2). Biochemistry, Vol.49 (No.37). pp. 8033-8042. ISSN 0006-2960
Mahenthiralingam, Eshwar, Song, Lijiang, White, J. (Judith), Wilmot, Ceri, Sass, Andrea, Marchbank, Angela and Challis, Gregory L.. (2010) Burkholderia ambifaria produces a polyketide antibiotic that inhibits Burkholderia multivorans and other Burkholderia cepacia complex species. Pediatric Pulmonology, Vol.45 (No.S33). p. 345. ISSN 8755-6863
Oke, Muse, Carter, Lester G., Johnson, Kenneth A., Liu, Huanting, McMahon, Stephen A., Yan, Xuan, Kerou, Melina, Weikart, Nadine D., Kadi, Nadia, Sheikh, Md. Arif et al.
(2010)
The Scottish Structural Proteomics Facility : targets, methods and outputs.
Journal of Structural and Functional Genomics, Vol.11
(No.2).
pp. 167-180.
ISSN 1345-711X
Nieselt, Kay, Battke, Florian, Herbig, Alexander, Bruheim, Per, Wentzel, Alexander, Jakobsen, Øyvind M., Sletta, Håvard, Alam, Mohammad T., Merlo, Maria E., Moore, Jonathan D. et al.
.
(2010)
The dynamic architecture of the metabolic switch in Streptomyces coelicolor.
BMC Genomics, Vol.11
(Article 10).
ISSN 1471-2164
Corre, Christophe and Challis, Gregory L. (2010) Exploiting genomics for new natural product discovery in prokaryotes. In: Mander, Lewis N. and Liu, Hung-wen, 1952-, (eds.) Comprehensive natural products II : chemistry and biology. Amsterdam ; Boston: Elsevier, pp. 429-453. ISBN 9780080453828
Corre, Christophe and Challis, Gregory L. (2009) New natural product biosynthetic chemistry discovered by genome mining. Natural Product Reports, Vol.26 (No.8). pp. 977-986. ISSN 0265-0568
Silby, Mark W., Cerdeño-Tárraga, Ana M., Vernikos, Georgios S., Giddens, Stephen R., Jackson, Robert W. (Robert Wilson), 1970-, Preston, Gail M., Zhang, Xue-Xian, Moon, Christina D., Gehrig, Stefanie M., Godfrey, Scott A. C. et al.
.
(2009)
Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens.
Genome Biology (Online), Vol.10
(No.5).
R51.
ISSN 1474-760X
Kadi, Nadia, Oves-Costales, Daniel, Barona-Gomez, Francisco and Challis, Gregory L.. (2009) Erratum : a new family of ATP-dependent oligomerization-macrocyclization biocatalysts. Nature Chemical Biology, Vol.5 (No.4). p. 266. ISSN 1552-4450
Barry, Sarah M. and Challis, Gregory L. (2009) Recent advances in siderophore biosynthesis. Current Opinion in Chemical Biology, Vol.13 (No.2). pp. 205-215. ISSN 1367-5931
Oves-Costales, Daniel, Song, Lijiang and Challis, Gregory L.. (2009) Enantioselective desymmetrisation of citric acid catalysed by the substrate-tolerant petrobactin biosynthetic enzyme AsbA. Chemical Communications (No.11). pp. 1389-1391. ISSN 1359-7345
Zerikly, Malek and Challis, Gregory L.. (2009) Strategies for the discovery of new natural products by genome mining. Chembiochem, Vol.10 (No.4). pp. 625-633. ISSN 1439-4227
Schmelz, Stefan, Kadi, N., McMahon, Stephen A., Song, Lijiang, Oves-Costales, Daniel, Oke, Muse, Liu, Huanting, Johnson, K. A. (Kenneth A.), Carter, Lester G., Botting, Catherine H., White, Malcolm F., Challis, Gregory L. and Naismith, James H.. (2009) AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis. Nature Chemical Biology, Vol.5 (No.3). pp. 174-182. ISSN 1552-4450
O'Rourke, S. (Sean), Wietzorrek, Andreas, Fowler, Kay, Corre, Christophe, Challis, Gregory L. and Chater, K. F.. (2009) Extracellular signalling, translational control, two repressors and an activator all contribute to the regulation of methylenomycin production in Streptomyces coelicolor. Molecular Microbiology, Vol.71 (No.3). pp. 763-778. ISSN 0950-382X
Kadi, Nadia and Challis, Gregory L.. (2009) Chapter 17 siderophore biosynthesis : a substrate specificity assay for nonribosomal peptide synthetase‐independent siderophore synthetases involving trapping of acyl‐adenylate intermediates with hydroxylamine. Methods in Enzymology, Vol.458 . pp. 431-457. ISSN 0076-6879
Kadi, N. and Challis, Gregory L. (2009) Siderophore biosynthesis: a substrate specificity assay for nonribosomal peptide synthetase-independent siderophore synthetases involving trapping of acyl-adenylate intermediates with hydroxylamine. Methods in Enzymology, Vol.458 . pp. 431-457. ISSN 0076-6879
Oves-Costales, Daniel, Kadi, Nadia and Challis, Gregory L. (2009) The long-overlooked enzymology of a nonribosomal peptide synthetase-independent pathway for virulence-conferring siderophore biosynthesis. Chemical Communications (No.43). pp. 6530-6541. ISSN 1359-7345
Chen, Kan, Rannulu, Nalaka S., Cai, Yang, Lane, P. (Pat), Liebl, Andrea L., Rees, Bernard B., Corre, Christophe, Challis, Gregory L. and Cole, Richard B., 1956-. (2008) Unusual odd-electron fragments from even-electron protonated prodiginine precursors using positive-ion electrospray tandem mass spectrometry. Journal of The American Society for Mass Spectrometry, Vol.19 (No.12). pp. 1856-1866. ISSN 1044-0305
Heather, Zoe, Holden, Matthew T. G., Steward, Karen F., Parkhill, Julian, Song, Lijiang, Challis, Gregory L., Robinson, Carl, Davis-Poynter, Nicholas and Waller, Andrew S.. (2008) A novel streptococcal integrative conjugative element involved in iron acquisition. Molecular Microbiology, Vol.70 (No.5). pp. 1274-1292. ISSN 0950-382X
Corre, Christophe, Song, Lijiang, O'Rourke, S. (Sean), Chater, K. F. and Challis, Gregory L.. (2008) 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining. Proceedings of the National Academy of Sciences of the United States of America, Vol.105 (No.45). pp. 17510-17515. ISSN 0027-8424
Kadi, Nadia, Song, Lijiang and Challis, Gregory L.. (2008) Bisucaberin biosynthesis : an adenylating domain of the BibC multi-enzyme catalyzes cyclodimerization of N-hydroxy-N-succinylcadaverine. Chemical Communications (No.41). pp. 5119-5121. ISSN 1359-7345
McMahon, Stephen A., Oke, Muse, Liu, Huanting, Johnson, K. A. (Kenneth A.), Carter, Lester, Kadi, Nadia, White, Malcolm F., Challis, Gregory L. and Naismith, James H.. (2008) Purification, crystallization and data collection of Pectobacterium chrysanthemi AcsD, a type A siderophore synthetase. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, Vol.64 (Pt.11). pp. 1052-1055. ISSN 1744-3091
Oves-Costales, Daniel, Kadi, Nadia, Fogg, Mark J., Song, Lijiang, Wilson, Keith S. and Challis, Gregory L.. (2008) Petrobactin biosynthesis: AsbB catalyzes condensation of spermidine with N-8-citryl-spermidine and its N-1-(3,4-dihydroxybenzoyl) derivative. Chemical Communications (No.34). pp. 4034-4036. ISSN 1359-7345
Montgomery, Laura J. and Challis, Gregory L.. (2008) Concise synthesis of key 3-polyenoyl-5-methylenefuran-2,4-dione putative intermediates in quartromicin biosynthesis. Synlett (No.14). pp. 2164-2168. ISSN 0936-5214
Kadi, Nadia, Arbache, Simon, Song, Lijiang, Oves-Costales, Daniel and Challis, Gregory L.. (2008) Identification of a gene cluster that directs putrebactin biosynthesis in Shewanella species : PubC catalyzes cyclodimerization of N-hydroxy-N-succinyiputrescine. Journal of the American Chemical Society, Vol.130 (No.32). pp. 10458-10459. ISSN 0002-7863
Challis, Gregory L.. (2008) Genome mining for novel natural product discovery. Journal of Medicinal Chemistry, Vol.51 (No.9). pp. 2618-2628. ISSN 0022-2623
Haynes, Stuart W., Sydor, Paulina K., Stanley, Anna E., Song, Lijiang and Challis, Gregory L.. (2008) Role and substrate specificity of the Streptomyces coelicolor RedH enzyme in undecylprodiginine biosynthesis. Chemical Communications (No.16). pp. 1865-1867. ISSN 1359-7345
Mo, SangJoon, Sydor, Paulina K., Corre, Christophe, Alhamadsheh, Mamoun M., Stanley, Anna E., Haynes, Stuart W., Song, Lijiang, Reynolds, Kevin A. and Challis, Gregory L.. (2008) Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis. Chemistry & Biology, Vol.15 (No.2). pp. 137-148. ISSN 1074-5521
Challis, Gregory L.. (2008) Mining microbial genomes for new natural products and biosynthetic pathways. Microbiology, Vol.154 (No.6). pp. 1555-1569. ISSN 1350-0872
Challis, Gregory L. and Hopwood, David A. (2007) Chemical biotechnology: biloactive small molecules - targets and discovery technologies. Current Opinion in Biotechnology, Vol.18 (No.6). pp. 475-477. ISSN 0958-1669
Kadi, Nadia, Oves-Costales, Daniel, Barona-Gomez, Francisco and Challis, Gregory L.. (2007) A new family of ATP-dependent oligomerization-macrocyclization biocatalysts. Nature, Vol.3 (No.10). pp. 652-656. ISSN 0028-0836
Oves-Costales, Daniel, Kadi, Nadia, Fogg, Mark J., Song, Lijiang, Wilson, Keith S. and Challis, Gregory L.. (2007) Enzymatic logic of anthrax stealth siderophore biosynthesis: AsbA catalyzes ATP-Dependent condensation of citric acid and spermidine. Journal of the American Chemical Society, Vol.129 (No.27). pp. 8416-8417. ISSN 0002-7863
Lautru, Sylvie, Oves-Costales, Daniel, Pernodet, Jean-Luc and Challis, Gregory L.. (2007) MbtH-like protein-mediated cross-talk between non-ribosomal peptide antibiotic and siderophore biosynthetic pathways in Streptomyces coelicolor M145. Microbiology, Vol.153 (No.5). pp. 1405-1412. ISSN 1350-0872
Haynes, Stuart W. and Challis, Gregory L. (2007) Non-linear enzymatic logic in natural product modular mega-synthases and -synthetases. Current Opinion in Drug Discovery & Development, Vol.10 (No.2). pp. 203-218. ISSN 1367-6733
Correl, Christophe and Challis, Gregory L. (2007) Heavy tools for genome mining. CHEMISTRY & BIOLOGY, 14 (1). pp. 7-9. ISSN 1074-5521
Thomson, Nicholas Robert, 1970-, Howard, Sarah, Wren, Brendan, Holden, Matthew T. G., Crossman, Lisa, Challis, Gregory L., Churcher, Carol, Mungall, Karen, Brooks, Karen, Chillingworth, Tracey et al.
.
(2006)
The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081.
PLOS Genetics, Vol.2
(No.12).
pp. 2039-2051.
ISSN 1553-7390
Song, Lijiang, Barona-Gomez, Francisco, Corre, Christophe, Xiang, Longkuan, Udwary, Daniel W., Austin, Michael B., Noel, Joseph P., Moore, Bradley S. and Challis, Gregory L.. (2006) Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 128 (46). pp. 14754-14755. ISSN 0002-7863
Barona-Gomez, Francisco, Lautru, Sylvie, Francou, Francois-Xavier, Leblond, Pierre, Pernodet, Jean-Luc and Challis, Gregory L.. (2006) Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877. MICROBIOLOGY-SGM, 152 (Part 11). pp. 3355-3366. ISSN 1350-0872
Challis, Gregory L. (2006) Engineering Escherichia coli to produce nonribosomal peptide antibiotics. Nature, 2 (8). pp. 398-400. ISSN 1552-4450
Stanley, Anna E., Walton, Laura J., Zerikly, Malek Kourdi, Corre, Christophe and Challis, Gregory L.. (2006) Elucidation of the Streptomyces coelicolor pathway to 4-methoxy-2,2 '-bipyrrole-5-carboxaldehyde, an intermediate in prodiginine biosynthesis. CHEMICAL COMMUNICATIONS (38). pp. 3981-3983. ISSN 1359-7345
This list was generated on Mon May 20 12:30:41 2013 BST.

