2022

Embacher, Peter A., Germanova, Tsvetelina E., Roscioli, Emanuele, McAinsh, Andrew D. and Burroughs, Nigel J. (2022) Bayesian inference of multi-point macromolecular architecture mixtures at nanometre resolution. PLoS Computational Biology, 18 (12). e1010765. doi:10.1371/journal.pcbi.1010765

Castrogiovanni, Cédric, Inchingolo, Alessio, Harrison, Jonathan U., Dudka, Damian, Sen, Onur, Burroughs, Nigel John, McAinsh, Andrew D. and Meraldi, Patrick (2022) Evidence for a HURP/EB free mixed-nucleotide zone in kinetochore-microtubules. Nature Communications, 13 . 4704. doi:10.1038/s41467-022-32421-x

Harrison, Jonathan, Sen, Onur, McAinsh, Andrew D. and Burroughs, Nigel John (2022) Kinetochore tracking in 3D from lattice light sheet imaging data with KiT. Bioinformatics, 38 (12). pp. 3315-3317. doi:10.1093/bioinformatics/btac330

2021

Germanova, Tsvetelina E., Roscioli, Emanuele, Harrison, Jonathan, McAinsh, Andrew D. and Burroughs, Nigel John (2021) Subcellular Euclidean distance measurements with multicolor fluorescence localization imaging in cultured cells. STAR Protocols, 2 (4). 100774. doi:10.1016/j.xpro.2021.100774

Sen, Onur, Harrison, Jonathan, Burroughs, Nigel John and McAinsh, Andrew D. (2021) Kinetochore life histories reveal an Aurora-B-dependent error correction mechanism in anaphase. Developmental Cell, 56 (22). pp. 3082-3099. doi:10.1016/j.devcel.2021.10.007

2020

Roscioli, Emanuele, Germanova, Tsvetelina E., Smith, Christopher A., Embacher, Peter A., Erent, Muriel, Thompson, Amelia I., Burroughs, Nigel John and McAinsh, Andrew D. (2020) Ensemble-Level Organization of Human Kinetochores and Evidence for Distinct Tension and Attachment Sensors. Cell Reports, 31 (4). p. 107535. doi:10.1016/j.celrep.2020.107535

2019

Jurić, Ivan, Hibberd, Julian, Blatt, Mike R. and Burroughs, Nigel John (2019) Computational modelling predicts substantial carbon assimilation gains for C3 plants with a single-celled C4 biochemical pump. PLoS Computational Biology, 15 (9). e1007373. doi:10.1371/journal.pcbi.1007373

Cheffings, Thomas H., Burroughs, Nigel John and Balasubramanian, Mohan K. (2019) Actin turnover ensures uniform tension distribution during cytokinetic actomyosin ring contraction. Molecular Biology of the Cell, 30 (8). pp. 933-1049. doi:10.1091/mbc.E18-08-0511

Bazarova, Alina, Nieduszynski, Conrad A, Akerman, Ildem and Burroughs, Nigel John (2019) Bayesian inference of origin firing time distributions, origin interference and licencing probabilities from Next Generation Sequencing data. Nucleic Acids Research, 47 (5). pp. 2229-2243. doi:10.1093/nar/gkz094

2018

Oliveira, Bruno M. P. M., Trinchet, Ricard, Otero Espinar, María Victoria, Pinto, Alberto and Burroughs, Nigel (2018) Modelling the suppression of autoimmunity after pathogen infection. Mathematical Methods in the Applied Sciences, 41 (18). pp. 8565-8570. doi:10.1002/mma.4899

Slator, Paddy J. and Burroughs, Nigel John (2018) A hidden Markov model for detecting confinement in single particle tracking trajectories. Biophysical Journal, 115 (9). pp. 1741-1754. doi:10.1016/j.bpj.2018.09.005

Wedagedera, J. R. and Burroughs, N. J. (2018) Comparison of a dual strategy for t-cell activation under inhibition of the CD4 receptor. Journal of Biological Systems, 26 (02). pp. 321-338. doi:10.1142/S0218339018500158

Peet, Daniel R., Burroughs, Nigel John and Cross, R. A. (2018) Kinesin expands and stabilizes the GDP-microtubule lattice. Nature Nanotechnology, 13 (5). pp. 386-391. doi:10.1038/s41565-018-0084-4

Smith, Chris A., Burroughs, Nigel John and McAinsh, Andrew D. (2018) Mitotic live-cell imaging at different timescales. In: Maiato, Helder and Schuh, Melina, (eds.) Mitosis and Meiosis Part B. Methods in Cell Biology, 145 . Cambridge, Massachuetts: Elsevier, pp. 1-27. ISBN 9780128141427

2017

Walker, Liam, Boddington, Clare, Jenkins, Dafyd J., Wang, Ying, Gronlund, Jesper T., Hulsmans, J., Kumar, Sanjeev, Patel, Dhaval, Moore, Jonathan D., Carter, Anthony, Samavedam, Siva, Bonomo, Giovanni, Hersh, David S., Coruzzi, Gloria‏, Burroughs, Nigel John and Gifford, Miriam L. (2017) Changes in gene expression in space and time orchestrate environmentally mediated shaping of root architecture. The Plant Cell, 29 (10). pp. 2393-2412. doi:10.1105/tpc.16.00961

Jurić, Ivan, González-Pérez, Vinicio, Hibberd, Julian, Edwards, Gerald and Burroughs, Nigel John (2017) Size matters for single-cell C4 photosynthesis in Bienertia. Journal of Experimental Botany, 68 (2). pp. 255-267. doi:10.1093/jxb/erw374

2016

Smith, Chris A., McAinsh, Andrew D. and Burroughs, Nigel John (2016) Human kinetochores are swivel joints that mediate microtubule attachments. eLife, 5 . e16159. doi:10.7554/eLife.16159

Cheffings, Thomas H., Burroughs, Nigel John and Balasubramanian, Mohan K. (2016) Actomyosin ring formation and tension generation in eukaryotic cytokinesis. Current Biology, 26 (15). R719-R737. doi:10.1016/j.cub.2016.06.071

Barchinger, Sarah E., Pirbadian, Sahand, Sambles, Christine, Baker, Carol S., Leung, Kar Man, Burroughs, Nigel John, El-Naggar, Mohamed Y., Golbeck, John H. and Spormann, A. M. (2016) Regulation of gene expression in Shewanella oneidensis MR-1 during electron acceptor limitation and bacterial nanowire formation. Applied and Environmental Microbiology, 82 (17). pp. 5428-5443. doi:10.1128/AEM.01615-16

Armond, Jonathan W., Vladimirou, Elina, McAinsh, Andrew D. and Burroughs, Nigel John (2016) KiT : a MATLAB package for kinetochore tracking. Bioinformatics, 32 (12). pp. 1917-1919. doi:10.1093/bioinformatics/btw087

2015

Armond, Jonathan W., Harry, Edward, McAinsh, Andrew D. and Burroughs, Nigel John (2015) Inferring the forces controlling metaphase kinetochore oscillations by reverse engineering system dynamics. PLoS Computational Biology, 11 (11). e1004607. doi:10.1371/journal.pcbi.1004607

Slator, Paddy J., Cairo, Christopher W. and Burroughs, Nigel John (2015) Detection of diffusion heterogeneity in single particle tracking trajectories using a hidden Markov model with measurement noise propagation. PLoS One, 10 (10). e0140759. doi:10.1371/journal.pone.0140759

Burroughs, Nigel John, Harry, Edward and McAinsh, Andrew D. (2015) Super-resolution kinetochore tracking reveals the mechanisms of human sister kinetochore directional switching. eLife, 4 . e09500. doi:10.7554/eLife.09500

Armond, Jonathan W., Vladimirou, Elina, Erent, Muriel, McAinsh, Andrew D. and Burroughs, Nigel John (2015) Probing microtubule polymerisation state at single kinetochores during metaphase chromosome motion. Journal of Cell Science, Volume 128 (Number 10). pp. 1991-2001. doi:10.1242/jcs.168682

2014

Bryan, Samantha J., Burroughs, Nigel John, Shevela, Dmitriy, Yu, Jianfeng, Rupprecht, Eva, Liu, Lu-Ning, Mastroianni, Giulia, Xue, Quan, Llorente-Garcia, Isabel, Leake, Mark C., Eichacker, Lutz A., Schneider, Dirk, Nixon, Peter J. and Mullineaux, Conrad W. (2014) Localisation and interactions of the Vipp1 protein in cyanobacteria. Molecular Microbiology, Volume 94 (Number 5). pp. 1179-1195. doi:10.1111/mmi.12826

Wood, Graham, Burroughs, Nigel John, Evans, David J. and Ryabov, Eugene V. (2014) Error correction and diversity analysis of population mixtures determined by NGS. PeerJ PrePrints, Volume 2 . Article number e645. doi:10.7717/peerj.645

Wang, Ying, Penfold, Christopher A., Hodgson, D. A., Gifford, Miriam L. and Burroughs, Nigel John (2014) Correcting for link loss in causal network inference caused by regulator interference. Bioinformatics, Volume 30 (Number 19). pp. 2779-2786. doi:10.1093/bioinformatics/btu388

Wood, Graham, Ryabov, Eugene V., Fannon, Jessica, Moore, Jonathan D., Evans, David J. and Burroughs, Nigel John (2014) MosaicSolver : a tool for determining recombinants of viral genomes from pileup data. Nucleic Acids Research, Volume 42 (Number 16). Article number e123. doi:10.1093/nar/gku524

Ryabov, Eugene V., Wood, Graham, Fannon, Jessica, Moore, Jonathan D., Bull, James C. (James Christopher), Chandler, Dave, Mead, A. (Andrew), Burroughs, Nigel John and Evans, David J. (2014) A virulent strain of deformed wing virus (DWV) of honeybees (Apis mellifera) prevails after varroa destructor-mediated, or in vitro, transmission. PLoS Pathogens, 10 (6). e1004230. doi:10.1371/journal.ppat.1004230

2012

Thomas, L., Hodgson, D. A., Wentzel, A., Nieselt, K., Ellingsen, T. E., Moore, Jonathan D., Morrissey, Edward R., Legaie, Roxane, Wohlleben, W., Rodriguez-Garcia, A., Martin, J. F., Burroughs, Nigel John, Wellington, E. M. H. and Smith, M. C. M. (2012) Metabolic switches and adaptations deduced from the proteomes of Streptomyces coelicolor wild type and phoP mutant grown in batch culture. Molecular & Cellular Proteomics, Vol.11 (No.2). M111.013797. doi:10.1074/mcp.M111.013797

Iqbal, Mudassar, Mast, Yvonne, Amin, Rafat, Hodgson, D. A., Wohlleben, W. and Burroughs, Nigel John (2012) Extracting regulator activity profiles by integration of de novo motifs and expression data : characterizing key regulators of nutrient depletion responses in Streptomyces coelicolor. Nucleic Acids Research, Vol.40 (No.12). pp. 5227-5239. doi:10.1093/nar/gks205

Martín, Juan F. , Santos-Beneit, Fernando, Rodríguez-García, Antonio , Sola-Landa, Alberto , Smith, Margaret C. M., Ellingsen, Trond E., Nieselt, Kay , Burroughs, Nigel John and Wellington, E. M. H. (2012) Transcriptomic studies of phosphate control of primary and secondary metabolism in Streptomyces coelicolor. Applied Microbiology and Biotechnology, Vol.95 (No.1). pp. 61-75. doi:10.1007/s00253-012-4129-6

2011

Tsibidis, George D., Burroughs, Nigel John, Gaze, William H. and Wellington, E. M. H. (2011) Semi-automated Acanthamoeba polyphaga detection and computation of Salmonella typhimurium concentration in spatio-temporal images. Micron, Vol.42 (No.8). pp. 911-920. doi:10.1016/j.micron.2011.06.010

Morrissey, Edward R., Juárez, Miguel A., Denby, Katherine J. and Burroughs, Nigel John (2011) Inferring the time-invariant topology of a nonlinear sparse gene regulatory network using fully Bayesian spline autoregression. Biostatistics, Vol.12 (No.4). pp. 682-694. doi:10.1093/biostatistics/kxr009

Burroughs, Nigel John, Köhler, Karsten, Miloserdov, Vladimir, Dustin, Michael L., Van der Merwe, P. Anton and Davis, Daniel M. (2011) Boltzmann energy-based image analysis demonstrates that extracellular domain size differences explain protein segregation at immune synapses. PLoS Computational Biology, Vol.7 (No.8). e1002076. doi:10.1371/journal.pcbi.1002076

Bryan, Samantha J., Burroughs, Nigel John, Evered, Carol, Sacharz, Joanna, Nenninger, Anja, Mullineaux, Conrad W. and Spence, Edward M. (2011) Loss of the SPHF homologue Slr1768 leads to a catastrophic failure in the maintenance of thylakoid membranes in synechocystis sp. PCC 6803. PLoS One, Vol.6 (No.5). e19625. doi:10.1371/journal.pone.0019625

Burroughs, Nigel John, Ferreira, M. (Miguel), Oliveira, B. M. P. M. and Pinto, Alberto A. (2011) Autoimmunity arising from bystander proliferation of T cells in an immune response model. Mathematical and Computer Modelling, Volume 53 (Numbers 7-8). pp. 1389-1393. doi:10.1016/j.mcm.2010.01.020

Burroughs, Nigel John, Oliveira, B. M. P. M., Pinto, A. A. and Ferreira, M. (2011) Immune response dynamics. Mathematical and Computer Modelling, Volume 53 (Numbers 7-8). pp. 1410-1419. doi:10.1016/j.mcm.2010.02.040

Vladimirou, Elina, Harry, Edward, Burroughs, Nigel John and McAinsh, Andrew D. (2011) Springs, clutches and motors : driving forward kinetochore mechanism by modelling. Chromosome Research, Volume 19 (Number 3). pp. 409-421. doi:10.1007/s10577-011-9191-x

Moore, Jonathan D., Jironkin, Aleksey, Chandler, Dave, Burroughs, Nigel John, Evans, David J. and Ryabov, Eugene V. (2011) Recombinants between Deformed wing virus and Varroa destructor virus-1 may prevail in Varroa destructor-infested honeybee colonies. Journal of General Virology, Vol.92 . pp. 156-161. doi:10.1099/vir.0.025965-0

Burroughs, Nigel John, Ferreira, M. (Miguel), Oliveira, Bruno M. P. M. and Pinto, Alberto A. (2011) A transcritical bifurcation in an immune response model. Journal of Difference Equations and Applications, Vol.17 (No.7). pp. 1101-1106. doi:10.1080/10236190903095291

2010

Pinto, A. A., Burroughs, Nigel John, Ferreira, M. and Oliveira, B. M. P. M. (2010) Dynamics of immunological models. Acta Biotheoretica, Vol.58 (No.4). pp. 391-404. doi:10.1007/s10441-010-9117-6

Köhler, Karsten, Xiong, Shiqiu, Brzostek, Joanna, Mehrabi, Maryam, Eissmann, Philipp, Harrison, Alice, Cordoba, Shaun-Paul, Oddos, Stephane, Miloserdov, Vladimir, Gould, Keith, Burroughs, Nigel John, Van der Merwe, Philip Anton and Davis, Daniel M. (2010) Matched sizes of activating and inhibitory receptor/ligand pairs are required for optimal signal integration by human Natural Killer cells. PL o S One, Vol.5 (No.11). e15374. doi:10.1371/journal.pone.0015374

Morrissey, Edward R., Juárez, Miguel A., Denby, Katherine J. and Burroughs, Nigel John (2010) On reverse engineering of gene interaction networks using time course data with repeated measurements. Bioinformatics, Vol.26 (No.18). pp. 2305-2312. doi:10.1093/bioinformatics/btq421

Yang, J., Koehler, K., Davis, D. M. and Burroughs, Nigel John (2010) An improved strip FRAP method for estimating diffusion coefficients : correcting for the degree of photobleaching. Journal of Microscopy, Vol.238 (No.3). pp. 240-253. doi:10.1111/j.1365-2818.2009.03347.x

(2010) The dynamic architecture of the metabolic switch in Streptomyces coelicolor. BMC Genomics, Vol.11 (Article 10). doi:10.1186/1471-2164-11-10

(2010) The dynamic architecture of the metabolic switch in Streptomyces coelicolor. BMC Genomics, 11 . p. 10. doi:DOI: 10.1186/1471-2164-11-10

2009

Whitelam, Stephen, Bretschneider, Till and Burroughs, Nigel John (2009) Transformation from spots to waves in a model of actin pattern formation. Physical Review Letters, Vol.102 (No.19). Article: 198103. doi:10.1103/PhysRevLett.102.198103

Berg, Laila, Lale, Rahmi, Bakke, Ingrid, Burroughs, Nigel John and Valla, Svein (2009) The expression of recombinant genes in Escherichia colican be strongly stimulated at the transcript production level by mutating the DNA-region corresponding to the 5′-untranslated part of mRNA. Microbial Biotechnology, Vol.2 (No.3). pp. 379-389. doi:10.1111/j.1751-7915.2009.00107.x

Berg, Laila, Lale, Rahmi, Bakke, Ingrid, Burroughs, Nigel John and Valla, Svein (2009) The expression of recombinant genes inEscherichia colican be strongly stimulated at the transcript production level by mutating the DNA-region corresponding to the 5′-untranslated part of mRNA. Microbial Biotechnology, Volume 2 (Number 3). pp. 379-389. doi:10.1111/j.1751-7915.2009.00107.x

2008

Bryan, Michael J., Burroughs, Nigel John, Spence, Edward M., Clokie, Martha R. J., Mann, Nicholas H. and Bryan, Samantha J. (2008) Evidence for the intense exchange of MazG in marine cyanophages by horizontal gene transfer. PL o S One, Vol.3 (No.4). doi:10.1371/journal.pone.0002048

Burroughs, Nigel John, Oliveira, B. M. P. M., Pinto, Alberto A. and Sequeira, H. J. T. (2008) Sensibility of the quorum growth thresholds controlling local immune responses. Mathematical and Computer Modelling, Vol.47 (No.7-8). pp. 714-725. doi:10.1016/j.mcm.2007.06.007

2007

Burroughs, Nigel John and Marenduzzo, Davide (2007) Nonequilibrium-driven motion in actin networks: comet tails and moving beads. Physical Review Letters, Vol.98 (No.23). Article: 238302. doi:10.1103/PhysRevLett.98.238302

Jow, H., Amos, W., Luo, H., Zhang, Y. and Burroughs, Nigel John (2007) A markov chain Monte Carlo method for estimating population mixing using Y-chromosome markers: mixing of the Han people in China. Annals of Human Genetics, Vol.71 (No.3). pp. 407-420. doi:10.1111/j.1469-1809.2006.00329.x

Burroughs, Nigel John and van der Merwe, P. Anton (2007) Stochasticity and spatial heterogeneity in T-cell activation. Immunological Reviews, Vol.216 (No.1). pp. 69-80. doi:10.1111/j.1600-065X.2006.00486.x

Chattopadhyay, Amit K. and Burroughs, Nigel John (2007) Close contact fluctuations : the seeding of signalling domains in the immunological synapse. EPL (Europhysics Letters), Volume 77 (Number 4). doi:10.1209/0295-5075/77/48003

2006

Burroughs, Nigel John, Lazic, Zorana and van der Merwe, P. Anton (2006) Ligand detection and discrimination by spatial relocalization: A kinase-phosphatase segregation model of TCR activation. Biophysical Journal, Vol.91 (No.5). pp. 1619-1629. doi:10.1529/biophysj.105.080044

Wedagedera, J. R. and Burroughs, Nigel John (2006) T-Cell activation: a queuing theory analysis at low agonist density. Biophysical Journal, Vol.91 (No.5). pp. 1604-1618. doi:10.1529/biophysj.105.066001

Burroughs, Nigel John, Mendes de Olivira, Bruno Miguel Paz and Pinto, Alberto A. (2006) Regulatory T cell adjustment of quorum growth thresholds and the control of local immune responses. Journal of Theoretical Biology, Volume 241 (Number 1). pp. 134-141. doi:10.1016/j.jtbi.2005.11.010

Burroughs, Nigel John and Marenduzzo, Davide (2006) Growth of a semi-flexible polymer close to a fluctuating obstacle: application to cytoskeletal actin fibres and testing of ratchet models. In: Workshop on Biopolymers 2005, Trieste, ITALY, MAY 30-JUN 03, 2005. Published in: Journal of Physics-Condensed Matter, Volume 18 (Number 14 Sp. Iss. SI). S357-S374. ISSN 0953-8984. doi:10.1088/0953-8984/18/14/S17

2002

Burroughs, Nigel John and Wülfing, Christoph (2002) Differential segregation in a cell-cell contact interface: the dynamics of the immunological synapse. Biophysical Journal, Vol.83 (No.4). pp. 1784-1796. doi:10.1016/S0006-3495(02)73944-1