Journal Article

Abhishek, Abhishek, Doherty, Sally A., Maciewicz, Rose A., Muir, Kenneth, Zhang, Weiya and Doherty, Michael (2012) Chondrocalcinosis is common in the absence of knee involvement. Arthritis Research & Therapy, Volume 14 (Number 5). Article no. R205. doi:10.1186/ar4043

Abuhammad, Areej, Fullam, Elizabeth, Bhakta, Sanjib, Russell, Angela, Morris, Garrett, Finn, Paul and Sim, Edith (2014) Exploration of piperidinols as potential antitubercular agents. Molecules, Volume 19 (Number 10). pp. 16274-16290. doi:10.3390/molecules191016274

Ailloud, Florent, Didelot, Xavier, Woltemate, Sabrina, Pfaffinger, Gudrun, Overmann, Jörg, Bader, Ruth Christiane, Schulz, Christian, Malfertheiner, Peter and Suerbaum, Sebastian (2019) Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps. Nature Communications, 10 (1). 2273 . doi:10.1038/s41467-019-10050-1

Al-Khudairy, Lena, Flowers, Nadine, Wheelhouse, Rebecca, Ghannam, Obadah, Hartley, Louise, Stranges, Saverio and Rees, Karen (2017) Vitamin C supplementation for the primary prevention of cardiovascular disease. Cochrane Database of Systematic Reviews . doi:10.1002/14651858.CD011114.pub2

Alberti, Fabrizio, Khairudin, Khairunisa, Venegas, Edith Rodriguez, Davies, Jonathan A., Hayes, Patrick M., Willis, Christine L., Bailey, Andy M. and Foster, Gary D. (2017) Heterologous expression reveals the biosynthesis of the antibiotic pleuromutilin and generates bioactive semi-synthetic derivatives. Nature Communications, 8 (1). 1831. doi:10.1038/s41467-017-01659-1

Alokail, Majed S., Sabico, Shaun, Al-Saleh, Yousef, Al-Daghri, Nasser M., Alkharfy, Khalid M., Vanhoutte, Paul M. and McTernan, P. G. (Philip G.) (2013) Effects of probiotics in patients with diabetes mellitus type 2 : study protocol for a randomized, double-blind, placebo-controlled trial. Trials, Volume 14 (Number 1). Article number 195. doi:10.1186/1745-6215-14-195

(2019) Effect of point-of-care C-reactive protein testing on antibiotic prescription in febrile patients attending primary care in Thailand and Myanmar : an open-label, randomised, controlled trial. The Lancet Global Health, 7 (1). E119-E131. doi:10.1016/S2214-109X(18)30444-3

Andersson, Robert, Kroon, Tobias, Almquist, Joachim, Jirstrand, Mats, Oakes, Nicholas D., Evans, Neil D., Chappel, Michael J. and Gabrielsson, Johan (2017) Modeling of free fatty acid dynamics : insulin and nicotinic acid resistance under acute and chronic treatments. Journal of Pharmacokinetics and Pharmacodynamics, 44 (3). pp. 203-222. doi:10.1007/s10928-017-9512-6

Anonye, Blessing (2016) General commentary on : alternatives to antibiotic growth promoters in animals. Frontiers in Veterinary Science, 3 . 74. doi:10.3389/fvets.2016.00074

Arduini, Arduino, Bonomini, Mario and Zammit, Victor A. (2016) Defining the potential antidepressant mode of action of acetyl-L-carnitine. Proceedings of the National Academy of Sciences of the United States of America, 113 (39). E5698-E5699. doi:10.1073/pnas.1612025113

Armoiry, Xavier, Connock, M., Tsertsvadze, Alexander, Cummins, Ewen, Melendez-Torres, G. J., Royle, Pamela and Clarke, Aileen (2018) Ixazomib for relapsed or refractory multiple myeloma : review from an evidence review group on a NICE single technology appraisal. PharmacoEconomics . doi:10.1007/s40273-018-0644-3 (In Press)

Atari, M. I., Chappell, M. J. (Michael J.), Errington, Rachel J., Smith, Paul J. and Evans, Neil D. (2011) Kinetic modelling of the role of the aldehyde dehydrogenase enzyme and the breast cancer resistance protein in drug resistance and transport. Computer Methods and Programs in Biomedicine, Vol.104 (No.2). pp. 93-103. doi:10.1016/j.cmpb.2010.06.008

(2018) Addressing the under-reporting of adverse drug reactions in public health programs controlling HIV/AIDS, Tuberculosis and Malaria : a prospective cohort study. PLoS One, 13 (8). e0200810. doi:10.1371/journal.pone.0200810

Awasthi, Shalini, Gupta, Shalini, Tripathi, Ravi and Nair, Nisanth N. (2018) Mechanism and kinetics of Aztreonam hydrolysis catalyzed by class-C β-lactamase : a temperature-accelerated sliced sampling study. The Journal of Physical Chemistry B, 122 (15). pp. 4299-4308. doi:10.1021/acs.jpcb.8b01287

Bailey, Andy M., Alberti, Fabrizio, Kilaru, Sreedhar, Collins, Catherine M., de Mattos-Shipley, Kate, Hartley, Amanda J., Hayes, Patrick, Griffin, Alison, Lazarus, Colin M., Cox, Russell J., Willis, Christine L., O’Dwyer, Karen, Spence, David W. and Foster, Gary D. (2016) Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production. Scientific Reports, 6 (1). doi:10.1038/srep25202

Ballesta, Annabelle, Innominato, Pasquale F., Dallmann, Robert, Rand, D. A. (David A.) and Lévi, Francis A. (2017) Systems chronotherapeutics. Pharmacological Reviews, 69 (2). pp. 161-199. doi:10.1124/pr.116.013441

Baltatzis, Minas, Mason, James, Chandrabalan, Vishnu, Stathakis, Panagiotis, McIntyre, Ben, Jegatheeswaran, Santhalingam, Jamdar, Saurabh, O'Reilly, Derek A. and Siriwardena, Ajith K. (2016) Antibiotic use in acute pancreatitis : an audit of current practice in a tertiary centre. Pancreatology, 16 (6). pp. 946-951. doi:10.1016/j.pan.2016.08.012

Barry, Nicolas P. E. and Sadler, P. J. (2012) Dicarba-closo-dodecarborane-containing half-sandwich complexes of ruthenium, osmium, rhodium and iridium : biological relevance and synthetic strategies. Chemical Society Reviews, Vol.41 (No.8). pp. 3264-3279. doi:10.1039/c2cs15300a

Bauducel, M., Piriou, V., Dussart, C., Aulagner, G. and Armoiry, Xavier (2017) Current trends in vasopressor use to the operating room : a pharmacoepidemiologic study in French teaching and military hospitals. Annales Pharmaceutiques Françaises . doi:10.1016/j.pharma.2017.02.001

Beadle, Jonathan D., Knuhtsen, Astrid, Hoose, Alex, Raubo, Piotr, Jamieson, Andrew G. and Shipman, Michael (2017) Solid-phase synthesis of oxetane modified peptides. Organic Letters, 19 (12). pp. 3303-3306. doi:10.1021/acs.orglett.7b01466

Bell, David J., Nyirongo, Suzgo K., Mukaka, Mavuto, Zijlstra, Ed E., Plowe, Christopher V., Molyneux, Malcolm E., Ward, Steve A. and Winstanley, Peter (2008) Sulfadoxine-pyrimethamine–based combinations for malaria : a randomised blinded trial to compare efficacy, safety and selection of resistance in Malawi. PLoS ONE, Vol.3 (No.2). e1578. doi:10.1371/journal.pone.0001578

Bergenholm, Linnéa, Parkinson, J., Mettetal, J., Evans, Neil D., Chappell, M. J. and Collins, T. (2017) Predicting QRS and PR interval prolongations in humans using nonclinical data. British Journal of Pharmacology, 174 (19). pp. 3268-3283. doi:10.1111/bph.13940

Black, C. (Corrinda), Cummins, E. (Ewen), Royle, Pamela, Philip, S. and Waugh, Norman (2007) The clinical effectiveness and cost-effectiveness of inhaled insulin in diabetes mellitus : a systematic review and economic evaluation. Health Technology Assessment, Vol.11 (No.33).

Blindauer, Claudia A., Sigel, Astrid, Operschall, Bert P. , Griesser, Rolf, Holý, Antonín and Sigel, Helmut (2016) Extent of intramolecular π stacks in aqueous solution in mixed-ligand copper(II) complexes formed by heteroaromatic amines and the anticancer and antivirally active 9-[2-phosphonomethoxy)ethyl]guanine (PMEG).✩ a comparison with related acyclic nucleotide analogues. Polyhedron, 103 (Part B). pp. 248-260. doi:10.1016/j.poly.2015.02.022

Boger, Elin, Evans, Neil D., Chappell, M. J. (Michael J.), Lundqvist, A., Ewing, P., Wigenborg, A. and Friden, M. (2016) Systems pharmacology approach for prediction of pulmonary and systemic pharmacokinetics and receptor occupancy of inhaled drugs. CPT : Pharmacometrics & Systems Pharmacology, 5 (4). pp. 201-210. doi:10.1002/psp4.12074

Boon, J. M., Abrahams, Peter H., Meiring, J. H. and Welch, T. (2004) Lumbar puncture for the generalist. South African Family Practice, Volume 46 (Number 2). pp. 38-42.

Brabec, Viktor, Howson, Suzanne E., Kaner, Rebecca A., Lord, Rianne M., Malina, Jaroslav, Phillips, Roger M., Abdallah, Qasem M. A., McGowan, Patrick C., Rodger, Alison and Scott, Peter (2013) Metallohelices with activity against cisplatin-resistant cancer cells : does the mechanism involve DNA binding? Chemical Science, Volume 4 (Number 12). pp. 4407-4416. doi:10.1039/c3sc51731d

Brilli, Matteo, Trabocchi, Andrea, Weil, Tobias, Cavalieri, Duccio and Stefanini, Irene (2017) Relations between effects and structure of small bicyclic molecules on the complex model system saccharomyces cerevisiae. Frontiers in Pharmacology, 8 . 170. doi:10.3389/fphar.2017.00170

Brockhurst, Michael A., Harrison, Freya, Veening, Jan-Willem , Harrison, Ellie , Blackwell, Grace , Iqbal , Zamin and Maclean , Craig (2019) Assessing evolutionary risks of resistance for new antimicrobial therapies. Nature Ecology and Evolution, 3 . pp. 515-517. doi:10.1038/s41559-019-0854-x

Bruijnincx, Pieter C. A. and Sadler, P. J. (2009) Controlling platinum, ruthenium, and osmium reactivity for anticancer drug design. Advances in Inorganic Chemistry, Vol.61 . pp. 1-62. doi:10.1016/S0898-8838(09)00201-3

Bunte, Kerstin, Smith, David J., Chappell, M. J. (Michael J.), Hassan-Smith, Zaki K., Tomlinson, Jeremy W., Arlt, Wiebke and Tiňo, Peter (2018) Learning pharmacokinetic models for in vivo glucocorticoid activation. Journal of Theoretical Biology, 455 . pp. 222-231. doi:10.1016/j.jtbi.2018.07.025

Bycroft, Michael (2017) Iatrochemistry and the evaluation of mineral waters in France, 1600-1750. Bulletin of the History of Medicine, 91 (2). pp. 303-330. doi:10.1353/bhm.2017.0028

Campbell, Norm RC , He , Feng J, Tan, Monique, Cappuccio, Francesco, Neal, Bruce, Woodward, Mark, Cogswell, Mary E, McLean, Rachael, Arcand, JoAnne, MacGregor, Graham A , Whelton, Paul A, Jula, Antti, L’Abbe, Mary R, Cobb, Laura K and Lackland, Daniel T (2019) The International Consortium for Quality Research on Dietary Sodium/Salt (TRUE) position statement on the use of 24-hour, spot and short duration (less than 24-hours) timed urine collections to assess dietary sodium intake. Journal of Clinical Hypertension . doi:10.1111/jch.13551 (In Press)

(2019) A patient safety toolkit for family practices. Journal of Patient Safety . p. 1. doi:10.1097/PTS.0000000000000471

(2018) A patient safety toolkit for family practices. Journal of Patient Safety . doi:10.1097/PTS.0000000000000471 (In Press)

Cappuccio, Francesco, Buchanan, Laura A., Ji, Chen, Siani, Alfonso and Miller, Michelle A. (2016) Systematic review and meta-analysis of randomised controlled trials on the effects of potassium supplements on serum potassium and creatinine. BMJ Open, 6 (8). e011716. doi:10.1136/bmjopen-2016-011716

Carnes, Dawn, Homer, Kate, Underwood, Martin, Pincus, Tamar, Rahman, A. (Anisur) and Taylor, Stephanie J. C. (2013) Pain management for chronic musculoskeletal conditions : the development of an evidence-based and theory-informed pain self-management course. BMJ Open, Volume 3 (Number 11). Article number e003534. doi:10.1136/bmjopen-2013-003534

Chadarevian, Rita, Eastell, R. (Richard), Ross, Richard J. M., Newell-Price, John and Randeva, Harpal S. (2013) Mifepristone reduces insulin resistance in patient volunteers with adrenal incidentalomas that secrete low levels of cortisol : a pilot study. PLoS One, Volume 8 (Number 4). e60984. doi:10.1371/journal.pone.0060984

Chappell, M. J. (Michael J.), Evans, Neil D., Errington, Rachel J., Khan, I. A., Campbell, L., Ali, Reza, Godfrey, Keith and Smith, Paul J. (2008) A coupled drug kinetics-cell cycle model to analyse the response of human cells to intervention by topotecan. Computer Methods and Programs in Biomedicine, Vol.89 (No.2). pp. 169-178. doi:10.1016/j.cmpb.2007.11.002

Cheung, S. Y. Amy, Evans, Neil D., Chappell, M. J. (Michael J.), Godfrey, Keith, Smith, Paul J. and Errington, Rachel J. (2008) Exploration of the intercellular heterogeneity of topotecan uptake into human breast cancer cells through compartmental modelling. Mathematical Biosciences, Vol.213 (No.2). pp. 119-134. doi:10.1016/j.mbs.2008.03.008

Clar, Christine, Tsertsvadze, Alexander, Court, Rachel A., Hundt, Gillian, Clarke, Aileen and Sutcliffe, P. (Paul) (2014) Clinical effectiveness of manual therapy for the management of musculoskeletal and non-musculoskeletal conditions : systematic review and update of UK evidence report. Chiropractic & Manual Therapies, Volume 22 (Number 1). Article number 12. doi:10.1186/2045-709X-22-12

Collins, Teresa, Bergenholm, Linnéa, Abdulla, Tariq, Yates, J. W. T., Evans, Neil D., Chappell, M. J. (Michael J.) and Mettetal, J. T. (2015) Modeling and simulation approaches for cardiovascular function and their role in safety assessment. CPT : Pharmacometrics & Systems Pharmacology, 4 (3). pp. 175-188. doi:DOI: 10.1002/psp4.18

Cooper, K. (Katy), Ph. D., Madan, Jason, Whyte, Sophie, Stevenson, M. (Matt) and Akehurst, Ron L. (2011) Granulocyte colony-stimulating factors for febrile neutropenia prophylaxis following chemotherapy : systematic review and meta-analysis. BMC Cancer, Volume 11 (Number 1). Article:404. doi:10.1186/1471-2407-11-404

Couper, Keith, Laloo, Ryan, Field, Richard A., Perkins, Gavin D., Thomas, Matthew and Yeung, Joyce (2019) Prophylactic antibiotic use following cardiac arrest : a systematic review and meta-analysis. Resuscitation . doi:10.1016/j.resuscitation.2019.04.047 (In Press)

Coveney, Catherine, Williams, Simon J. and Gabe, Jonathan (2019) Enhancement imaginaries : exploring public understandings of pharmaceutical cognitive enhancing drugs. Drugs : Education, Prevention and Policy, 26 (4). pp. 319-328. doi:10.1080/09687637.2019.1593318

Cree, Ian A. (2013) Designing personalised cancer treatments. Journal of Controlled Release, Volume 172 (Number 2). pp. 405-409. doi:10.1016/j.jconrel.2013.07.007

Cui, Li‐li, Golubczyk, Dominika, Tolppanen, Anna‐Maija, Boltze, Johannes and Jolkkonen, Jukka (2019) Cell therapy for ischemic stroke : are differences in preclinical and clinical study design responsible for the translational loss of efficacy? Annals of Neurology, 86 (1). pp. 5-16. doi:10.1002/ana.25493

Day, Simon, Jonker, Anneliene Hechtelt, Lau, Lilian Pek Lian, Hilgers, Ralf-Dieter, Irony, Ilan, Larsson, Kristina, Roes, Kit C. B. and Stallard, Nigel (2018) Recommendations for the design of small population clinical trials. Orphanet Journal of Rare Diseases, 13 (1). 195. doi:10.1186/s13023-018-0931-2

DeMonaco, Harold J., Ali, Ayfer and Hippel, Eric von (2006) The major role of clinicians in the discovery of off-label drug therapies. Pharmacotherapy, 26 (3). pp. 323-332. doi:10.1592/phco.26.3.323

Del Regno, Annalaura and Notman, Rebecca (2018) Permeation pathways through lateral domains in model membranes of skin lipids. Physical Chemistry Chemical Physics, 20 (4). pp. 2162-2174. doi:10.1039/c7cp03258g

Dilly, Suzanne J., Clark, Andrew J., Marsh, Andrew, Mitchell, Daniel A., Cain, Ricky, Fishwick, Colin W. G. and Taylor, Paul C. (2017) A chemical genomics approach to drug reprofiling in oncology : antipsychotic drug risperidone as a potential adenocarcinoma treatment. Cancer Letters, 393 . pp. 16-21. doi:10.1016/j.canlet.2017.01.042

Dimmock, N. J., Rainsford, Edward W., Scott, P. D. (Paul D.) and Marriott, Anthony C. (2008) Influenza virus protecting RNA : an effective prophylactic and therapeutic antiviral. Journal of Virology, Vol.82 (No.17). pp. 8570-8578. doi:10.1128/JVI.00743-08

Easton, A. J. (Andrew J.), Scott, P. D. (Paul D.), Edworthy, Nicole Lynn, Meng, Bo, Marriott, Anthony C. and Dimmock, N. J. (2011) A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo. Vaccine, Vol.29 (No.15). pp. 2777-2784. doi:10.1016/j.vaccine.2011.01.102

Eissa, Ahmed M., Abdulkarim, Ali, Sharples, Gary J. and Cameron, Neil R. (2016) Glycosylated nanoparticles as efficient antimicrobial delivery agents. Biomacromolecules, 17 (8). pp. 2672-2679. doi:10.1021/acs.biomac.6b00711

Evans, Neil D. (2011) Optimal oral drug dosing via application of the contraction mapping theorem. Biomedical Signal Processing and Control, Vol.6 (No.1). pp. 57-63. doi:10.1016/j.bspc.2010.06.006

Evans, Neil D., Cheung, S. Y. Amy and Yates, James W. T. (2018) Structural identifiability for mathematical pharmacology : models of myelosuppression. Journal of Pharmacokinetics and Pharmacodynamics . doi:10.1007/s10928-018-9569-x (In Press)

Evans, Neil D., Dimelow, Richard and Yates, James W. T. (2014) Modelling of tumour growth and cytotoxic effect of docetaxel in xenografts. Computer Methods and Programs in Biomedicine, Volume 114 (Number 3). e3-e13. doi:10.1016/j.cmpb.2013.06.014

Farrer, Nicola J., Salassa, Luca and Sadler, P. J. (2009) Photoactivated chemotherapy (PACT) : the potential of excited-state d-block metals in medicine. Dalton Transactions, Vol.48 . pp. 10690-10701. doi:10.1039/b917753a

Field, Sarah L., Dasgupta, Tathagata, Cummings, Michele, Savage, Richard S., Adebayo, Julius, McSara, Hema, Gunawardena, Jeremy and Orsi, Nicolas M. (2015) Bayesian modeling suggests that IL-12 (p40), IL-13 and MCP-1 drive murine cytokine networks in vivo. BMC Systems Biology, 9 (46). pp. 1-22. doi:10.1186/s12918-015-0226-3

Ford, John A., Elders, Andrew, Shyangdan, D. (Deepson), Royle, Pamela and Waugh, Norman (2012) The relative clinical effectiveness of ranibizumab and bevacizumab in diabetic macular oedema : an indirect comparison in a systematic review. BMJ, Vol.345 . e5182. doi:10.1136/bmj.e5182

Ford, John A., Lois, Noemi, Royle, Pamela, Clar, C., Shyangdan, D. and Waugh, Norman (2013) Current treatments in diabetic macular oedema : systematic review and meta-analysis. BMJ Open, Volume 3 (Number 3). Article no. e002269. doi:10.1136/bmjopen-2012-002269

Freeman, Karoline, Saunders, Mark P., Uthman, Olalekan A., Taylor-Phillips, Sian, Connock, M., Court, Rachel A., Gurung, T., Sutcliffe, P. (Paul) and Clarke, Aileen (2016) Is monitoring of plasma 5-fluorouracil levels in metastatic / advanced colorectal cancer clinically effective? A systematic review. BMC Cancer, 16 (1). doi:10.1186/s12885-016-2581-x

Fu, Y. (Ying), Habtemariam, Abraha, Basri, Aida M. B. H., Braddick, Darren, Clarkson, Guy J. and Sadler, P. J. (2011) Structure–activity relationships for organometallic osmium arene phenylazopyridine complexes with potent anticancer activity. Dalton Transactions (No.40). pp. 10553-10562. doi:10.1039/c1dt10937e

Gabe, Jonathan, Coveney, Catherine and Williams, Simon J. (2015) Prescriptions and proscriptions : moralising sleep medicines. Sociology of Health & Illness, 38 (4). pp. 627-644. doi:10.1111/1467-9566.12383

Gabe, Jonathan, Williams, Simon J. and Coveney, Catherine (2017) Prescription hypnotics in the news : a study of UK audiences. Social Science and Medicine, 174 . pp. 43-52. doi:10.1016/j.socscimed.2016.11.029

Gillaizeau, F., Chan, E., Trinquart, L., Colombet, I., Walton, Robert, Rège-Walther, M., Burnand, B. and Durieux, P. (2013) Computerized advice on drug dosage to improve prescribing practice. The Cochrane database of systematic reviews, 11 . CD002894. doi:doi: 10.1002/14651858.CD002894.pub3

Greene, Nicholas P., Kaplan, Elise, Crow, Allister and Koronakis, Vassilis (2018) Antibiotic resistance mediated by the MacB ABC transporter family : a structural and functional perspective. Frontiers in Microbiology, 9 . 950. doi:10.3389/fmicb.2018.00950

Griffin, Jamie T., Hollingsworth, T. Déirdre, Okell, Lucy C., Churcher, Thomas S., White, Michael, Hinsley, Wes, Bousema, Teun, Drakeley, Chris J., Ferguson, Neil M., Basáñez, María-Gloria and Ghani, Azra C. (2010) Reducing plasmodium falciparum malaria transmission in Africa : a model-based evaluation of intervention strategies. PLoS Medicine, Volume 7 (Number 8). Article no. e1000324. doi:10.1371/journal.pmed.1000324

Griffin, Xavier L., Achten, Juul, Parsons, Nicholas R. and Costa, Matthew L. (2013) Platelet-rich therapy in the treatment of patients with hip fractures: a single centre, parallel group, participant-blinded, randomised controlled trial. BMJ Open, Volume 3 (Number 6). Article number e002583. doi:10.1136/bmjopen-2013-002583

Griffin, Xavier L., Smith, Nicholas A., Parsons, Nicholas R. and Costa, Matthew L. (2010) Ultrasound and shockwave therapy for acute fractures in adults (protocol). Cochrane Database of Systematic Reviews (No.2). CD008579. doi:10.1002/14651858.CD008579

Griffiths, Frances, Lindenmeyer , Antje, Borkan , Jeffrey M., Donner Banzhoff , Norbert, Lamb, S. E. (Sallie E.), Parchman , Michael and Sturt, Jackie (2014) Case typologies, chronic illness and primary health care. Journal of Evaluation in Clinical Practice, Volume 20 (Number 4). pp. 513-521. doi:10.1111/jep.12070

Griffiths, Frances, Pepper, Jo, Jørstad-Stein , Ellen C., Fereday Smith, Jan, Hill, Lesley and Lamb, S. E. (Sallie E.) (2009) Group versus individual sessions delivered by a physiotherapist for female urinary incontinence: an interview study with women attending group sessions nested within a randomised controlled trial. BMC Women's Health, Vol.9 . doi:10.1186/1472-6874-9-25

Gurung, Tara, Ellard, David R., Mistry, Dipesh, Patel, Shilpa and Underwood, Martin (2015) Identifying potential moderators for response to treatment in low back pain : a systematic review. Physiotherapy, 101 (3). pp. 243-251. doi:10.1016/j.physio.2015.01.006

Hall, Adam J., Chappell, M. J. (Michael J.), Aston, John A. D. and Ward, Stephen A. (2013) Pharmacokinetic modelling of the anti-malarial drug artesunate and its active metabolite dihydroartemisinin. Computer Methods and Programs in Biomedicine . doi:10.1016/j.cmpb.2013.05.010

Hardelid, Pia, Ghebremichael Weldeselassie, Yonas, Whitaker, Heather, Rait, Greta, Gilbert, Ruth and Petersen, Irene (2018) Effectiveness of live attenuated influenza vaccine in preventing amoxicillin prescribing in preschool children : a self-controlled case series study. Journal of Antimicrobial Chemotherapy, 73 (3). pp. 779-786. doi:10.1093/jac/dkx463

Havemann, Judith, Yurkovich, Marie E., Jenkins, Robert, Harringer, Sophia, Tao, Weixin, Wen, Shishi, Sun, Yuhui, Leadlay, P. F. and Tosin, Manuela (2017) Chemical probing of thiotetronate bio-assembly. Chemical Communications, 53 (11). pp. 1912-1915. doi:10.1039/C6CC09933E

Hind, D., Tappenden, P., Tumur, I., Eggington, S., Sutcliffe, P. (Paul) and Ryan, A. (2008) The use of irinotecan, oxaliplatin and raltitrexed for the treatment of advanced colorectal cancer : systematic review and economic evaluation (review of NICE guidance no. 33). Health Technology Assessment, Vol.12 (No.15). pp. 1-182. doi:10.3310/hta12150

Hope, Emma C., Crump, Ron E., Hollingsworth, Deirdre, Smieszek, Timo, Robotham, Julie and Pouwels, Koen (2019) Identifying English practices that are high antibiotic prescribers accounting for comorbidities and other legitimate medical reasons for variation. eClinicalMedicine . doi:10.1016/j.eclinm.2018.12.003 (In Press)

Hrast, Martina, Jukič, Marko, Patin, Delphine, Tod, Julie, Dowson, Christopher G., Roper, David I., Barreteau, Hélène and Gobec, Stanislav (2018) In silico identification, synthesis and biological evaluation of novel tetrazole inhibitors of MurB. Chemical Biology & Drug Design, 91 (6). pp. 1101-1112. doi:10.1111/cbdd.13172

Iqbal, H. (Hasan), Ting, Stephen M. S. , Hamborg, Thomas, Imray, C. (Chris), Hewins, Susan, Banerjee, Prithwish, Bland, R. (Rosemary), Higgins, Rob and Zehnder, Daniel (2013) Reduced functional measure of cardiovascular reserve predicts admission to critical care unit following kidney transplantation. PLoS One, Volume 8 (Number 5). Article number e64335. doi:10.1371/journal.pone.0064335

Janzén, David, Bergenholm, Linnéa, Jirstrand, Mats, Parkinson, Joanna, Yates, James, Evans, Neil D. and Chappell, Michael J. (2016) Parameter identifiability of fundamental pharmacodynamic models. Frontiers in Physiology, 7 . 590. doi:10.3389/fphys.2016.00590

Janzén, David, Jirstrand, Mats, Evans, Neil D. and Chappell, M. J. (Michael J.) (2015) Structural identifiability in mixed-effects models : two different approaches. IFAC-PapersOnLine, 48 (20). pp. 563-568. doi:10.1016/j.ifacol.2015.10.201

Jeyaharan, Dhadchayini, Brackstone, Carla, Schouten, James, Davis, Paul and Dixon, Ann M. (2018) Characterisation of the carboxypeptidase G2 catalytic site and design of new inhibitors for cancer therapy. ChemBioChem, 19 (18). pp. 1959-1968. doi:10.1002/cbic.201800186

Jones, Gareth T., Mertens, Kathrin, Macfarlane, Gary J., Palmer, K. T., Coggon, D. (David), Dr., Walker-Bone, Karen, Burton, Kim, Heine, Peter J., McCabe, Candy, McNamee, Paul and McConnachie, Alex (2014) Maintained physical activity and physiotherapy in the management of distal upper limb pain : a protocol for a randomised controlled trial (the arm pain trial). BMC Musculoskeletal Disorders, Volume 15 (Number 1). Article number 71. doi:10.1186/1471-2474-15-71

Jordan, Robert W., Smith, Nicholas A., Saithna, Adnan, Sprowson, Andrew P. and Foguet, Pedro (2014) Sensitivities, specificities, and predictive values of microbiological culture techniques for the diagnosis of prosthetic joint infection. BioMed Research International, Volume 2014 . pp. 1-5. Article number 180416. doi:10.1155/2014/180416

Joubert, Fanny, Yeo, R. Paul, Sharples, Gary J., Musa, Osama M., Hodgson, David R. W. and Cameron, Neil R. (2015) Preparation of an antibacterial poly(ionic liquid) graft copolymer of hydroxyethyl cellulose. Biomacromolecules, 16 (12). pp. 3970-3979. doi:10.1021/acs.biomac.5b01300

Kandala, Ngianga-Bakwin, Connock, M., Grove, Amy L., Sutcliffe, P. (Paul), Mohiuddin, Syed, Hartley, Louise, Court, Rachel A., Cummins, E., Gordon, Caroline and Clarke, Aileen (2013) Belimumab : a technological advance for systemic lupus erythematosus patients? Report of a systematic review and meta-analysis. BMJ Open, Volume 3 (Number 7). Article number e002852. doi:10.1136/bmjopen-2013-002852

Khan, Kamran, Mazuquin , Bruno, Canaway , Alastair, Petrou, Stavros and Bruce, J. (Julie) (2019) Systematic review of economic evaluations of exercise and physiotherapy for patients treated for breast cancer. Breast Cancer Research and Treatment . doi:10.1007/s10549-019-05235-7 (In Press)

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Uthman, Olalekan A., Saunders, Rachel, Sinclair, David, Graves, Patricia M., Gelband, Hellen, Clarke, Aileen and Garner, Paul (2014) Safety of 8-aminoquinolines given to people with G6PD deficiency : protocol for systematic review of prospective studies. BMJ Open, Volume 4 (Number 5). Article number e004664. doi:10.1136/bmjopen-2013-004664

Vajs, Jure, Proud, Conor, Brozovic, Anamaria, Gazvoda, Martin, Lloyd, Adrian J., Roper, David I., Osmak, Maja, Košmrlj, Janez and Dowson, Christopher G. (2017) Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis. European Journal of Medicinal Chemistry, 127 . pp. 223-234. doi:10.1016/j.ejmech.2016.12.060

Wang, Weishan, Yang, Tongjian, Li, Yihong, Li, Shanshan, Yin, Shouliang, Styles, Kathryn, Corre, Christophe and Yang, Keqian (2016) Development of a synthetic oxytetracycline-inducible expression system for streptomycetes using de novo characterized genetic parts. ACS Synthetic Biology, 5 (7). pp. 765-773. doi:10.1021/acssynbio.6b00087

Wason, James M. S., Jaki, Thomas and Stallard, Nigel (2013) Planning multi-arm screening studies within the context of a drug development program. Statistics in Medicine, Volume 32 (Number 20). pp. 3424-3435. doi:10.1002/sim.5787

Watkins, John, Marsh, Andrew, Taylor, Paul C. and Singer, Donald R. J. (2010) Personalized medicine : the impact on chemistry. Therapeutic Delivery, Vol.1 (No.5). pp. 651-665. doi:10.4155/tde.10.64

Weich, Scott, Pearce, Hannah L., Croft, Peter, Singh, Swaran P., Crome, Ilana B., Bashford, James and Frisher, Martin (2014) Effect of anxiolytic and hypnotic drug prescriptions on mortality hazards : retrospective cohort study. BMJ, Volume 348 . Article number g1996. doi:10.1136/bmj.g1996

Whale, Richard, Harris, Michael, Kavanagh, Gail, Wickramasinghe, Vijitha , Jones, Christopher I., Marwaha, Steven, Jethwa, Ketan, Ayadurai, Nirmalan and Thompson, Andrew David (2016) Effectiveness of antipsychotics used in first-episode psychosis : a naturalistic cohort study. BJ Psych Open, 2 (5). pp. 323-329. bjporcpsych002766.. doi:doi: 10.1192/bjpo.bp.116.002766

Whitehead, John, Kelly, P. J., Zhou, Yinghui, Stallard, Nigel, Thygesen, Helene and Bowman, Clive (2009) Action following the discovery of a global association between the whole genome and adverse event risk in a clinical drug-development programme. Pharmaceutical Statistics, Vol.8 (No.4). pp. 287-300. doi:10.1002/pst.357

Williams, Marie-Louise and Nolan, Jerry P. (2014) Is enteral feeding tolerated during therapeutic hypothermia? Resuscitation, 85 (11). pp. 1469-1472. doi:10.1016/j.resuscitation.2014.08.018

Williams, Mark A, Srikesavan, Cynthia, Heine, Peter J, Bruce, J. (Julie), Brosseau, Lucie, Hoxey-Thomas, Nicolette and Lamb, Sarah E (2018) Exercise for rheumatoid arthritis of the hand. Cochrane Database of Systematic Reviews . doi:10.1002/14651858.cd003832.pub3

Wilson, Paul (2017) Synthesis and applications of protein/peptide-polymer conjugates. Macromolecular Chemistry and Physics , 218 (9). 1600595. doi:10.1002/macp.201600595

Wong, Angel Y. S., Root, Adrian, Douglas, Ian J., Chui, Celine S. L., Chan, Esther W., Ghebremichael Weldeselassie, Yonas, Siu, Chung-Wah, Smeeth, Liam and Wong, Ian C. K. (2016) Cardiovascular outcomes associated with use of clarithromycin : population based study. BMJ, 352 . h6926. doi:10.1136/bmj.h6926

Wootton, Daniel G., Opara, Hyginus, Biagini, Giancarlo A., Kanjala, Maxwell K., Duparc, Stephan, Kirby, Paula L., Woessner, Mary, Neate, Colin, Nyirenda, Maggie, Blencowe, Hannah, Dube-Mbeye, Queen, Kanyok, Thomas, Ward, Stephen, Molyneux, Malcolm E., Dunyo, Sam and Winstanley, Peter (2008) Open-label comparative clinical study of chlorproguanil−dapsone fixed dose combination (Lapdap™) alone or with three different doses of artesunate for uncomplicated plasmodium falciparum malaria. PLoS One, Vol.3 (No.3). e1779. doi:10.1371/journal.pone.0001779

Yahara, Koji, Nakayama, Shu-ichi, Shimuta, Ken, Lee, Ken-ichi, Morita, Masatomo, Kawahata, Takuya, Kuroki, Toshiro, Watanabe, Yuko, Ohya, Hitomi, Yasuda, Mitsuru, Deguchi, Takashi, Didelot, Xavier and Ohnishi, Makoto (2018) Genomic surveillance of Neisseria gonorrhoeae to investigate the distribution and evolution of antimicrobial-resistance determinants and lineages. Microbial Genomics, 4 (8). doi:10.1099/mgen.0.000205

Yap, Kevin Yi-Lwern, Chui, Wai Keung and Chan, Alexandre (2011) Development of a chemotherapy regimen interaction database for the mobile internet : detecting interactions with psychotropics through OncoRx-MI. Informatics for Health and Social Care, Vol.36 (No.3). pp. 132-146. doi:10.3109/17538157.2011.584996

Yurkovich, Marie E., Jenkins, Robert, Sun, Yuhui, Tosin, Manuela and Leadlay, P. F. (2017) The polyketide backbone of thiolactomycin is assembled by an unusual iterative polyketide synthase. Chemical Communications, 53 (13). pp. 2182-2185. doi:10.1039/C6CC09934C

Zhao, Yao, (Researcher in chemistry), Farrer, Nicola J., Li, Huilin, Butler, Jennifer S. (Jennifer Suzanne), McQuitty, Ruth J., Habtemariam, Abraha, Wang, Fuyi and Sadler, P. J. (2013) De novo generation of singlet oxygen and ammine ligands by photoactivation of a platinum anticancer complex. Angewandte Chemie International Edition, Volume 52 (Number 51). pp. 13633-13637. doi:10.1002/anie.201307505

Zhou, Deyu, Miao, Lei and He, Yulan (2018) Position-aware deep multi-task learning for drug–drug interaction extraction. Artificial Intelligence in Medicine, 87 . pp. 1-8. doi:10.1016/j.artmed.2018.03.001

Zhou, Shanshan, Song, Lijiang, Masschelein, Joleen, Sumang, Felaine A. M., Papa, Irene A., Zulaybar, Teofila O., Custodio, Aileen B., Zabala, Daniel, Alcantara, Edwin P., Emmanuel de los Santos, L. C. and Challis, Gregory L. (2019) Pentamycin biosynthesis in Philippine Streptomyces sp. S816 : cytochrome P450-catalyzed installation of the C-14 hydroxyl group. ACS Chemical Biology (14). pp. 1305-1309. doi:10.1021/acschembio.9b00270 (In Press)

Zhu, Chongyu, Schneider, Elena K., Nikolaou, Vasiliki, Klein, Tobias, Li, Jian, Davis, Thomas P., Whittaker, Michael R., Wilson, Paul, Kempe, Kristian, Velkov, Tony and Haddleton, David M. (2017) Hydrolyzable poly[poly(ethylene glycol) methyl ether acrylate]–colistin prodrugs through copper-mediated photoinduced living radical polymerization. Bioconjugate Chemistry . doi:10.1021/acs.bioconjchem.7b00242

Zong, Jingyi, Cobb, Steven L. and Cameron, Neil R. (2017) Peptide-functionalized gold nanoparticles : versatile biomaterials for diagnostic and therapeutic applications. Biomaterials Science, 5 (5). pp. 872-886. doi:10.1039/c7bm00006e

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Book Item

Despotou, George, Korkontzelos, Ioannis, Matragkas, Nicholas, Bilici, Eda and Arvanitis, Theodoros N. (2018) Structuring clinical decision support rules for drug safety using natural language processing. In: Hasman, Arie and Gallos, Parisis and Liaskos, Joseph and Househ, Mowafa S. and Mantas, John , (eds.) Data, informatics and technology : an inspiration for improved healthcare. Studies in Health Technology and Informatics, 251 . I O S Press, pp. 89-92. ISBN 9781614998792

Journal Item

Cooke, Matthew (Professor of clinical systems design), Marsh, J. L., Clark, Michael, Nakash, Rachel A., Jarvis, Rosemary M., Hutton, Jane, Szczepura, Ala, Wilson, Sue, Dr and Lamb, S. E. (Sallie E.) (2009) Treatment of severe ankle sprain : a pragmatic randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of three types of mechanical ankle support with tubular bandage : the CAST trial. Health Technology Assessment, Vol.13 (No.13). pp. 1-121. doi:10.3310/hta13130

Submitted Journal Article

Grandjean, Thomas R. B., Chappell, M. J. (Michael J.), Yates, J. W. T., Jones, Kevin, Wood, Gemma and Coleman, Tanya (2011) Compartmental modelling of the pharmacokinetics of a breast cancer resistance protein. Computer Methods and Programs in Biomedicine, Vol.104 (No.2). pp. 81-92. doi:10.1016/j.cmpb.2010.08.018

Report

Waugh, Norman, Cummins, E. (Ewen), Shyangdan, D. (Deepson), Court, Rachel A. and Mohiuddin, Syed (2012) Exenatide prolonged-release suspension for injection in combination with oral antidiabetic therapy for the treatment of type 2 diabetes. Manchester: National Institute for Health and Clinical Excellence (NICE). (NICE technology appraisal guidance).

Thesis or Dissertation

Abraham, Kristin (2018) In vitro and in vivo chronopharmacology of a new generation of an organometallic anticancer drug complex. PhD thesis, University of Warwick.

Andersson, Karl Robert (2017) Dose-response-time data analysis. PhD thesis, University of Warwick.

Bergenholm, Linnéa (2017) Predicting QRS and PR interval prolongations in humans using nonclinical data. PhD thesis, University of Warwick.

Blatherwick, Eleanor Q. (2013) Imaging mass spectrometry approaches for the detection and localisation of drug compounds and small molecules in tissue. PhD thesis, University of Warwick.

Canning, Peter (2009) The prolyl oligopeptidase family enzymes: structural basis of inhibition. PhD thesis, University of Warwick.

Casey-Green, Katherine (2011) A chemical genomics approach to human drug target discovery : with test of principle using Simvastatin. PhD thesis, University of Warwick.

Channon, Robert B. (2015) Development of electrochemical methods for the determination of pharmaceutical impurities. PhD thesis, University of Warwick.

Cheema, Ejaz (2015) The role of pharmacists in the management of chronic disease and prevention of adverse drug reactions. PhD thesis, University of Warwick.

Cload, Paul Andrew (1983) Pyrophosphate analogues as antiviral agents. PhD thesis, University of Warwick.

Delaney, Michael Paul (2001) Immunosuppressive drug interactions and resistance in mononuclear cells from renal transplant patients. MD thesis, University of Warwick.

Fu, Ying (2011) Organometallic osmium arene anticancer complexes. PhD thesis, University of Warwick.

Garnett, Khanungnit Kym (2004) British Indo-Asians with diabetes mellitus : their adherence and use of medicinal plants. PhD thesis, University of Warwick.

Griffin, Xavier L. (2012) The clinical effectiveness of biological treatment adjuncts in the management of acute and un-united fractures. PhD thesis, University of Warwick.

Halstead, Fenella (2017) Developing novel topical antimicrobial agents for the treatment of biofilm infections. PhD thesis, University of Warwick.

Hattersley, John G. (2009) Mathematical modelling of immune condition dynamics : a clinical perspective. PhD thesis, University of Warwick.

Heal, Jack W. (2013) Effects of ligand binding on the rigidity and mobility of proteins : a computational and experimental approach. PhD thesis, University of Warwick.

Hicks, Nigel John (1981) Studies on the effects of interferon on the phenotype or mouse fibroblasts that have been transformed by a murine sarcoma virus. PhD thesis, University of Warwick.

Holland, Richard J. (2009) The use of recently developed mass spectrometry approaches for the characterisation of biological mixtures. PhD thesis, University of Warwick.

Hughes, George Marc (2018) Design and mechanism of action of novel organoiridium(iii) azopyridine anticancer complexes. PhD thesis, University of Warwick.

Huxley, Martin (2006) Testosterone as a delivery vector for platinum(II) metallodrugs. PhD thesis, University of Warwick.

Kearney, Rebecca S. (2012) An investigation into accelerated rehabilitation strategies following an achilles tendon rupture. PhD thesis, University of Warwick.

Laspina, Stefan (2017) Factors influencing variation in blood product usage : an international perspective. PhD thesis, University of Warwick.

Lopatář, Ján (2011) Regulation of cortical excitability and seizure activity by purines. PhD thesis, University of Warwick.

Martino, Angela (2013) A new serogroup B meningococcal vaccine : biophysical characterisation of its protein components. PhD thesis, University of Warwick.

McKenzie-Mills, Marie (2009) Developing a community of practice for trainers: towards a culture of conscience in clinical research. PhD thesis, University of Warwick.

Mihalyi, Agnes (2014) Screening for novel inhibitors of phospho-MurNAc-pentapeptide translocase MraY. PhD thesis, University of Warwick.

Rodolis, Maria T. (2013) Interaction of translocase MraY with the antibacterial E protein from bacteriophage ΦX174. PhD thesis, University of Warwick.

Romero-Canelón, Isolda (2012) Design and mechanism of action of organometallic anticancer complexes. PhD thesis, University of Warwick.

Royall, Sophie C. (2012) Anti-inflammatory SSTR2 ligands. PhD thesis, University of Warwick.

Rushton, Alison (2004) An exploration of the construct of Masters level clinical practice. PhD thesis, University of Warwick.

Sedgfield, Amber (2015) Mindfulness during the perinatal period. DClinPsych thesis, University of Warwick.

Simpson, Daniel H. (2017) Antimicrobial metallohelices : discovery and mechanistic investigation. PhD thesis, University of Warwick.

Suberu, John O. (2013) Analysis of plant materials for molecules of pharmaceutical importance. PhD thesis, University of Warwick.

Sydor, Paulina K. (2010) Elucidation of the prodiginine biosynthetic pathway in Streptomyces coelicolor A3(2). PhD thesis, University of Warwick.

Taylor, M. Clare (1999) Occupational therapists : empowerors or oppressors? : a study of occupational therapy students' attitudes towards disabled people. PhD thesis, University of Warwick.

Tighe, Bernice J. (2016) The lived experience of dietitians’ involvement in decision-making related to artificial nutrition and hydration. PhD thesis, University of Warwick.

Tomlinson, James Allen (1968) The structure and properties of dicoumarol and related compounds. PhD thesis, University of Warwick.

Trägårdh, Magnus (2017) Input estimation in nonlinear dynamical systems for drug-discovery applications. PhD thesis, University of Warwick.

Vernooij, Robbin (2017) New materials for cancer imaging and therapy. PhD thesis, University of Warwick and Monash University.

Wootton, Christopher (2016) Exploring biomolecules, metallodrugs, and their interactions via the use of UHR-FT-ICR mass spectrometry. PhD thesis, University of Warwick.

Zhang, Fang, (Researcher in medical sciences) (2013) Dysfunctional thiamine metabolism in experimental diabetes and pharmokinetic modelling. PhD thesis, University of Warwick.

Dataset

Maruyoshi, Keisuke, Iuga, Dinu, Watts, Abigail E., Hughes, Colan E., Harris, Kenneth D.M. and Brown, Steven P. (2017) Data for Assessing the detection limit of a minority solid-state form of a pharmaceutical by 1H double-quantum MAS NMR spectroscopy. [Dataset]

Ratamero, Erick Martins and Römer, Rudolf A. (2017) Data for touching proteins with virtual bare hands: how to visualize protein-drug complexes and their dynamics in virtual reality. [Dataset]

Tomás, Ruben M. F., Martyn, Benjamin T., Bailey, Trisha L. and Gibson, Matthew I. (2018) Data for Engineering cell surfaces by covalent grafting of synthetic polymers to metabolically-labeled glycans. [Dataset]

Zhu, Chongyu, Schneider, Elena K., Nikolaou, Vasiliki, Klein, Tobias, Li, Jian, Davis, Thomas P., Whittaker, Michael R., Wilson, Paul, Kempe, Kristian, Velkov, Tony and Haddleton, David M. (2017) Data for Hydrolyzable poly[poly(ethylene glycol) methyl ether acrylate]–colistin prodrugs through copper-mediated photoinduced living radical polymerization. [Dataset]

Öster, Carl, Walkowiak, Grzegorz P., Hughes, Dallas E., Spoering, Amy L., Peoples, Aaron J., Catherwood, Anita C., Tod, Julie A., Lloyd, Adrian J., Herrmann, Torsten, Lewis, Kim, Dowson, Christopher G. and Lewandowski, Józef R. (2018) Data for Structural studies suggest aggregation as one of the modes of action for teixobactin. [Dataset]